Involvement of enniatins-induced cytotoxicity in human HepG2 cells.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Toxicology Letters

• Publication date

  2013-04-12

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.toxlet.2013.01.014PMID 23370383
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Study of the potential toxicity of enniatins A, A(1), B, B(1) by evaluation of duodenal and colonic bioavailability applying an in vitro method by Caco-2 cells.

  2012cited by this paper
• Differential Mitochondrial Toxicity Screening and Multi-Parametric Data Analysis

  2012cited by this paper
• Comparative cytotoxicity study of enniatins A, A₁, A₂, B, B₁, B₄ and J₃ on Caco-2 cells, Hep-G₂ and HT-29.

  2011cited by this paper
• Toxigenicity of enniatins from Western Australian Fusarium species to brine shrimp (Artemia franciscana).

  2011cited by this paper
• Beauvericin and enniatin: emerging toxins and/or remedies?

  2010influential reference
• Involvement of mitochondrial pathway in NCTD-induced cytotoxicity in human hepG2 cells

  2010cited by this paper
• The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis.

  2010cited by this paper
• Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells

  2010cited by this paper
• Fusarial toxin-induced toxicity in cultured cells and in isolated mitochondria involves PTPC-dependent activation of the mitochondrial pathway of apoptosis.

  2009cited by this paper
• Oxidative stress and DNA interactions are not involved in Enniatin- and Beauvericin-mediated apoptosis induction.

  2009influential reference
• The emerging Fusarium toxin enniatin B: in-vitro studies on its genotoxic potential and cytotoxicity in V79 cells in relation to other mycotoxins

  2009cited by this paper
• Flow cytometry applications in the food industry

  2009cited by this paper
• The Fusarium toxin enniatin B exerts no genotoxic activity, but pronounced cytotoxicity in vitro.

  2009cited by this paper
• Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation.

  2009cited by this paper
• A bioassay for the simultaneous measurement of metabolic activity, membrane integrity, and lysosomal activity in cell cultures.

  2008cited by this paper
• Emerging Fusarium -Mycotoxins Fusaproliferin, Beauvericin, Enniatins, And Moniliformin—A Review

  2008cited by this paper
• Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells.

  2007cited by this paper
• Fumonisin B1 alters cell cycle progression and interleukin-2 synthesis in swine peripheral blood mononuclear cells.

  2007cited by this paper
• Cytotoxicity of enniatins A, A1, B, B1, B2 and B3 from Fusarium avenaceum.

  2006influential reference
• Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins.

  2006cited by this paper
• Estrogenic and clastogenic potential of the mycotoxin alternariol in cultured mammalian cells.

  2006cited by this paper
• Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae.

  2005cited by this paper
• Myelotoxicity of trichothecenes and apoptosis: an in vitro study on human cord blood CD34+ hematopoietic progenitor.

  2005cited by this paper
• Determination of beauvericin and four other enniatins in grain by liquid chromatography-mass spectrometry.

  2004cited by this paper
• Investigation of the electrophysiological properties of enniatins.

  2004influential reference
• Mitochondrial pathway is involved in hydrogen‐peroxide‐induced apoptotic cell death of oligodendrocytes

  2004cited by this paper
• Detection and Differentiation of Trichothecene and Enniatin-Producing Fusarium Species on Small-Grain Cereals

  2004cited by this paper
• Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line.

  2004cited by this paper
• Apoptosis induction by the satratoxins and other trichothecene mycotoxins: relationship to ERK, p38 MAPK, and SAPK/JNK activation.

  2000cited by this paper
• Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure.

  1998influential reference

• ENN A1 and B1 In Vitro Toxicological Effects on 2D and 3D Organ-on-Chip HepaRG Liver Cells.

  2026cites this paper
• Citrinin-Induced Cellular Damage: Insights from SH-SY5Y Cell Line Studies

  2025cites this paper
• Enniatin Mycotoxins in Food: A Systematic Review of Global Occurrence, Biosynthesis, and Toxicological Impacts on In Vitro Human Cell Models

  2025influential citation
• Investigating the individual and mixture cytotoxicity of co-occurring aflatoxin B1, enniatin B, and sterigmatocystin on gastric, intestinal, hepatic, and renal cellular models.

  2024cites this paper
• Cytotoxic Effects of Major and Emerging Mycotoxins on HepaRG Cells and Transcriptomic Response after Exposure of Spheroids to Enniatins B and B1

  2024cites this paper
• Cell cycle and enzymatic activity alterations induced by ROS production in human neuroblastoma cells SH-SY5Y exposed to Fumonisin B1, Ochratoxin A and their combination.

  2023cites this paper
• Biogenic Zinc oxide nanoparticles from Celosia argentea: toward improved antioxidant, antibacterial, and anticancer activities

  2023cites this paper
• Individual and combined effect of acrylamide, fumitremorgin C and penitrem A on human neuroblastoma SH-SY5Y cells.

  2023cites this paper
• In Vitro Effects of Enniatin A on Steroidogenesis and Proliferation of Bovine Granulosa Cells

  2022cites this paper
• Pumpkin extract and fermented whey individually and in combination alleviated AFB1- and OTA-induced alterations on neuronal differentiation invitro.

  2022cites this paper
• Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity.

  2021cites this paper
• The expedient application of microbial fermentation after whole-wheat milling and fractionation to mitigate mycotoxins in wheat-based products

  2021cites this paper
• Fusarium Mycotoxins, Their Metabolites (Free, Emerging, and Masked), Food Safety Concerns, and Health Impacts

  2021cites this paper
• Sterigmatocystin-induced DNA damage triggers cell-cycle arrest via MAPK in human neuroblastoma cells

  2021cites this paper
• Neurotoxicity of zearalenone's metabolites and beauvericin mycotoxins via apoptosis and cell cycle disruption.

  2021cites this paper
• Proteomics evaluation of enniatins acute toxicity in rat liver.

  2021cites this paper
• Mycotoxin Identification and In Silico Toxicity Assessment Prediction in Atlantic Salmon

  2020cites this paper
• T-2 toxin and its metabolites: characterization, cytotoxic mechanisms and adaptive cellular response in human hepatocarcinoma (HepG2) cells.

  2020cites this paper
• Enniatin B induces dosage-related apoptosis or necrosis in mouse blastocysts leading to deleterious effects on embryo development

  2020influential citation
• Mycotoxins Occurrence, Toxicity and Detection Methods

  2020cites this paper
• Beauvericin and Enniatins: In Vitro Intestinal Effects

  2020cites this paper
• Cytotoxicity, Genotoxicity and Disturbance of Cell Cycle in HepG2 Cells Exposed to OTA and BEA: Single and Combined Actions

  2019cites this paper
• Public Health Nutrition: Assessing Evidence to Determine Policy and Practice

  2019cites this paper
• Enniatin B1 exerts embryotoxic effects on mouse blastocysts and induces oxidative stress and immunotoxicity during embryo development

  2018cites this paper
• Structural Diversity and Biological Activities of Cyclic Depsipeptides from Fungi

  2018cites this paper
• Beauvericin and enniatin B effects on a human lymphoblastoid Jurkat T-cell model.

  2018cites this paper
• In vitro mechanisms of Beauvericin toxicity: A review.

  2018cites this paper
• DNA damage‐induced apoptosis and mitogen‐activated protein kinase pathway contribute to the toxicity of dronedarone in hepatic cells

  2018cites this paper
• Micronucleus induction and cell cycle alterations produced by deoxynivalenol and its acetylated derivatives in individual and combined exposure on HepG2 cells.

  2018cites this paper
• Fusarium Mycotoxins in Food

  2017cites this paper
• Health Risks Associated with Exposure to Filamentous Fungi

  2017cites this paper
• A Review of the Mycotoxin Enniatin B

  2017cites this paper
• Enniatin and Beauvericin Biosynthesis in Fusarium Species: Production Profiles and Structural Determinant Prediction

  2017cites this paper
• Organic versus conventional food: A comparison regarding food safety

  2017cites this paper
• Occurrence and co-occurrence of Fusarium mycotoxins in wheat grains and wheat flour from Romania

  2017cites this paper
• Presence of Enniatins and Beauvericin in Romanian Wheat Samples: From Raw Material to Products for Direct Human Consumption

  2017cites this paper
• Mechanisms of beauvericin toxicity and antioxidant cellular defense.

  2016cites this paper
• Binary and tertiary combination of alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on HepG2 cells: Toxic effects and evaluation of degradation products.

  2016cites this paper
• Simultaneous analysis of twenty-six mycotoxins in durum wheat grain from Italy

  2016cites this paper
• Dichlorodiphenyldichloroethylene exposure reduces r‐GCS via suppressed Nrf2 in HepG2 cells

  2016cites this paper
• Cytochrome P450-mediated metabolism of triclosan attenuates its cytotoxicity in hepatic cells

  2016cites this paper
• Mechanisms of tolvaptan-induced toxicity in HepG2 cells.

  2015cites this paper
• Evaluation of Emerging Fusarium mycotoxins beauvericin, Enniatins, Fusaproliferin and Moniliformin in Domestic Rice in Iran

  2015cites this paper
• BCL2 promotor methylation and miR-15a/16-1 upregulation is associated with sanguinarine-induced apoptotic death in rat HSC-T6 cells.

  2015cites this paper
• Cytotoxic effects and degradation products of three mycotoxins: alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol in liver hepatocellular carcinoma cells.

  2015cites this paper
• Enniatin A1, enniatin B1 and beauvericin on HepG2: Evaluation of toxic effects.

  2015cites this paper
• Biosynthesis of beauvericin and enniatins in vitro by wheat Fusarium species and natural grain contamination in an area of central Italy.

  2015cites this paper
• Blood, breast milk and urine: potential biomarkers of exposure and estimated daily intake of ochratoxin A: a review

  2015cites this paper
• Presence of ochratoxin A (OTA) mycotoxin in alcoholic drinks from southern European countries: wine and beer.

  2014cites this paper
• Evaluation of immunologic effect of Enniatin A and quantitative determination in feces, urine and serum on treated Wistar rats.

  2014cites this paper
• Emerging mycotoxins: enniatins (A, A1, B and B1) and beauvericin

  2014cites this paper
• Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway.

  2013cites this paper
• Reactive oxygen species involvement in apoptosis and mitochondrial damage in Caco-2 cells induced by enniatins A, A₁, B and B₁.

  2013cites this paper
• Beauvericin-induced cytotoxicity via ROS production and mitochondrial damage in Caco-2 cells.

  2013cites this paper
• Rotenone-induced oxidative stress and apoptosis in human liver HepG2 cells

  2013cites this paper