Evaluation of platelet distribution width in chronic obstructive pulmonary disease patients with pulmonary embolism.

BACKGROUND Platelets play an important role in the pathogenesis of pulmonary embolism (PE). We aimed to investigate whether there is a correlation between platelet distribution width (PDW) and chronic obstructive pulmonary disease (COPD) patients with PE. METHODS We conducted a retrospective study using 126 COPD patients with PE and 51 COPD patients without PE. Blood biomarkers, including PDW and d-dimer, were included. Odds ratios (OR) associated with PDW and interactions with d-dimer, SpO2 were estimated for PE. RESULTS PDW was higher in the COPD patients with PE group (p = 0.007). A higher PDW had a significantly increased risk of PE than a lower PDW (adjusted OR 2.724, 95% CI: 1.290-5.753). CONCLUSION PDW are elevated in COPD patients with PE and are associated with the risk of PE.

• Publication year

  2016

• Venue

  Biomarkers in Medicine

• Publication date

  2016-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.2217/bmm.15.112PMID 26567584
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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