The yeast transcriptome in aerobic and hypoxic conditions: effects of hap1, rox1, rox3 and srb10 deletions

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Molecular Microbiology

• Publication date

  2002-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.1365-2958.2002.02724.xPMID 11929514
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Rox1 Medited Repression

  2002cited by this paper
• Correspondence analysis applied to microarray data

  2001influential reference
• Interaction of a transcriptional repressor with the RNA polymerase II holoenzyme plays a crucial role in repression

  2001cited by this paper
• A Rox1‐independent hypoxic pathway in yeast. Antagonistic action of the repressor Ord1 and activator Yap1 for hypoxic expression of the SRP1/TIR1 gene

  2000cited by this paper
• Saccharomyces cerevisiae PAU genes are induced by anaerobiosis

  2000cited by this paper
• Processing and quality control of DNA array hybridization data

  2000influential reference
• Oxygen dependent repression in yeast

  2000cited by this paper
• Rox1 mediated repression. Oxygen dependent repression in yeast.

  2000cited by this paper
• Turning genes off by Ssn6-Tup1: a conserved system of transcriptional repression in eukaryotes.

  2000cited by this paper
• Transcript analysis of 203 novel genes from Saccharomyces cerevisiae in hap1 and rox1 mutant backgrounds.

  2000cited by this paper
• Roles of Transcription Factor Mot3 and Chromatin in Repression of the Hypoxic Gene ANB1 in Yeast

  2000influential reference
• Molecular mechanism of the multiple regulation of the Saccharomyces cerevisiae ATF1 gene encoding alcohol acetyltransferase

  1999cited by this paper
• Models for oxygen sensing in yeast: implications for oxygen-regulated gene expression in higher eucaryotes.

  1999cited by this paper
• GAL4 is regulated by the RNA polymerase II holoenzyme-associated cyclin-dependent protein kinase SRB10/CDK8.

  1999cited by this paper
• Genome-Wide Transcriptional Analysis of Aerobic and Anaerobic Chemostat Cultures of Saccharomyces cerevisiae

  1999cited by this paper
• Functional Relationships of Srb10-Srb11 Kinase, Carboxy-Terminal Domain Kinase CTDK-I, and Transcriptional Corepressor Ssn6-Tup1

  1998cited by this paper
• Transcriptional profiling on all open reading frames of Saccharomyces cerevisiae

  1998influential reference
• Dissecting the regulatory circuitry of a eukaryotic genome.

  1998cited by this paper
• The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat protein.

  1998cited by this paper
• Srb/mediator proteins interact functionally and physically with transcriptional repressor Sfl1

  1998cited by this paper
• Identification of Rox3 as a Component of Mediator and RNA Polymerase II Holoenzyme*

  1997cited by this paper
• The two isoenzymes for yeast NAD+‐dependent glycerol 3‐phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation

  1997cited by this paper
• Approaches to the study of Rox1 repression of the hypoxic genes in the yeast Saccharomyces cerevisiae.

  1997cited by this paper
• The DAN1 gene of S. cerevisiae is regulated in parallel with the hypoxic genes, but by a different mechanism.

  1997cited by this paper
• Rox3 and Rts1 function in the global stress response pathway in baker's yeast.

  1996cited by this paper
• Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast.

  1996cited by this paper
• Regulation by low temperatures and anaerobiosis of a yeast gene specifying a putative GPI‐anchored plasma membrane

  1996cited by this paper
• Characterization of an Upstream Activation Sequence and Two Rox1p-responsive Sites Controlling the Induction of the Yeast HEM13 Gene by Oxygen and Heme Deficiency*

  1996cited by this paper
• Mutations in target DNA elements of yeast HAP1 modulate its transcriptional activity without affecting DNA binding.

  1996cited by this paper
• Multiple elements and auto-repression regulate Rox1, a repressor of hypoxic genes in Saccharomyces cerevisiae.

  1995cited by this paper
• The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure.

  1994cited by this paper
• The ORD1 gene encodes a transcription factor involved in oxygen regulation and is identical to IXR1, a gene that confers cisplatin sensitivity to Saccharomyces cerevisiae.

  1994cited by this paper
• New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae

  1994cited by this paper
• The Rox1 repressor of the Saccharomyces cerevisiae hypoxic genes is a specific DNA-binding protein with a high-mobility-group motif

  1993cited by this paper
• Transcriptional control of AAC3 gene encoding mitochondrial ADP/ATP translocator in Saccharomyces cerevisiae by oxygen, heme and ROX1 factor.

  1993cited by this paper
• Multiple regulatory elements control expression of the gene encoding the Saccharomyces cerevisiae cytochrome P450, lanosterol 14 alpha-demethylase (ERG11).

  1992cited by this paper
• The Use of Carbon Dioxide Laser in Female Urology

  1991cited by this paper
• The ROX3 gene encodes an essential nuclear protein involved in CYC7 gene expression in Saccharomyces cerevisiae.

  1991cited by this paper
• ROX1 encodes a heme-induced repression factor regulating ANB1 and CYC7 of Saccharomyces cerevisiae

  1988influential reference
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Transformation of intact yeast cells treated with alkali cations.

  1984cited by this paper

• A synthetic ERFVII-dependent circuit in yeast sheds light on the regulation of early hypoxic responses of plants

  2025cites this paper
• Sustainable production and pharmaceutical applications of β-glucan from microbial sources.

  2023cites this paper
• Transcriptional regulation of ergosterol biosynthesis genes in response to iron deficiency

  2022cites this paper
• The HMGB Protein KlIxr1, a DNA Binding Regulator of Kluyveromyces lactis Gene Expression Involved in Oxidative Metabolism, Growth, and dNTP Synthesis

  2021cites this paper
• Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae

  2020cites this paper
• A programmable fate decision landscape underlies single-cell aging in yeast

  2020cites this paper
• UPC2 gene deletion modifies sterol homeostasis and susceptibility to metabolic inhibitors in Kluyveromyces lactis

  2020cites this paper
• The transcriptomic response of a wine strain of Lachancea thermotolerans to oxygen deprivation.

  2020cites this paper
• RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia

  2019cites this paper
• The regulation of iron homeostasis in the fungal human pathogen Candida glabrata.

  2019cites this paper
• Expresión de genes involucrados en enfermedades neurodegenerativas en especies de levaduras sometidas a estrés

  2018influential citation
• The HMGB protein Ixr1 interacts with Ssn8 and Tdh3 involved in transcriptional regulation

  2018cites this paper
• Fungal cytochrome P450 protein Cyp51: What we can learn from its evolution, regulons and Cyp51-based azole resistance

  2018cites this paper
• A Novel Sterol-Signaling Pathway Governs Azole Antifungal Drug Resistance and Hypoxic Gene Repression in Saccharomyces cerevisiae

  2017cites this paper
• Dual function of Ixr1 in transcriptional regulation and recognition of cisplatin-DNA adducts is caused by differential binding through its two HMG-boxes.

  2017cites this paper
• Increased heme synthesis in yeast induces a metabolic switch from fermentation to respiration even under conditions of glucose repression

  2017cites this paper
• BEORA - Biotechnology exploitation of orotic acid production

  2017cites this paper
• Measuring mRNA Levels Over Time During the Yeast S. cerevisiae Hypoxic Response.

  2017cites this paper
• Hypoxia and iron requirements are the main drivers in transcriptional adaptation of Kluyveromyces lactis during wine aerobic fermentation.

  2017cites this paper
• The effect of hypoxia on the lipidome of recombinant Pichia pastoris

  2017cites this paper
• Oxygen-responsive transcriptional regulation of lipid homeostasis in fungi: Implications for anti-fungal drug development.

  2017cites this paper
• Whole-genome Transcriptional Responses to Hypoxia in Respiration-proficient and Respiration-deficient Yeasts: Implication of the Mitochondrial Respiratory Chain in Oxygen-regulated Gene Expression

  2016cites this paper
• Sterol Regulatory Element Binding Protein (Srb1) Is Required for Hypoxic Adaptation and Virulence in the Dimorphic Fungus Histoplasma capsulatum

  2016cites this paper
• Time-Course Analysis of Gene Expression During the Saccharomyces cerevisiae Hypoxic Response

  2016cites this paper
• Compartmentalization of iron between mitochondria and the cytosol and its regulation.

  2015cites this paper
• Yap7 is a transcriptional repressor of nitric oxide oxidase in yeasts, which arose from neofunctionalization after whole genome duplication

  2015cites this paper
• Proteomic and Functional Consequences of Hexokinase Deficiency in Glucose-repressible Kluyveromyces lactis

  2014cites this paper
• Anaerobic Carbon Metabolism of Saccharomyces cerevisiae

  2014cites this paper
• Hypoxia and gene expression in eukaryotic microbes.

  2013cites this paper
• Recruitment of Tup 1 p and Cti 6 p regulates heme-deficient expression of Aft 1 p target genes

  2013cites this paper
• Regulation of Cytochrome C Oxidase Composition by Oxygen and Oxidative Stress

  2012cites this paper
• The yeast hypoxic responses, resources for new biotechnological opportunities

  2012cites this paper
• Kluyveromyces lactis: A Suitable Yeast Model to Study Cellular Defense Mechanisms against Hypoxia-Induced Oxidative Stress

  2012cites this paper
• Med19 promotes gastric cancer progression and cellular growth.

  2012cites this paper
• A dual signalling pathway for the hypoxic expression of lipid genes, dependent on the glucose sensor Rag4, is revealed by the analysis of the KlMGA2 gene in Kluyveromyces lactis.

  2012cites this paper
• Identification of transcription factors perturbed by the synthesis of high levels of a foreign protein in yeast saccharomyces cerevisiae

  2011cites this paper
• Knockdown of MED19 by lentivirus-mediated shRNA in human osteosarcoma cells inhibits cell proliferation by inducing cell cycle arrest in the G0/G1 phase.

  2011cites this paper
• Transcriptional Responses of Saccharomyces cerevisiae to Shift from Respiratory and Respirofermentative to Fully Fermentative Metabolism

  2011cites this paper
• The Hog1 Mitogen-Activated Protein Kinase Mediates a Hypoxic Response in Saccharomyces cerevisiae

  2011cites this paper
• Ixr1p and the control of the Saccharomyces cerevisiae hypoxic response

  2011cites this paper
• Suppression of MED19 expression by shRNA induces inhibition of cell proliferation and tumorigenesis in human prostate cancer cells.

  2011cites this paper
• Effects of oxygen provision on the physiology of baker's yeast Saccharomyces cerevisiae

  2010cites this paper
• Heme regulates protein homeostasis at transcription, protein translation, and degradation levels

  2010cites this paper
• Transcriptional Response to Hypoxia in the Aquatic Fungus Blastocladiella emersonii

  2010cites this paper
• Regulation of hypoxia adaptation: an overlooked virulence attribute of pathogenic fungi?

  2010cites this paper
• Effects of oxygen provision on the physiology of baker's yeast Saccharomyces cerevisiae

  2010cites this paper
• Hypoxische Adaptation des humanpathogenen Pilzes Candida albicans

  2010cites this paper
• Regulation of the Hypoxic Response in Candida albicans

  2010cites this paper
• Responses to hypoxia in fungal pathogens

  2009cites this paper
• Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae

  2009cites this paper
• Transcriptional response to mitochondrial NADH kinase deficiency in Saccharomyces cerevisiae.

  2009cites this paper
• Sugar metabolism, redox balance and oxidative stress response in the respiratory yeast Kluyveromyces lactis

  2009cites this paper
• Regulatory factors controlling transcription of Saccharomyces cerevisiae IXR1 by oxygen levels: a model of transcriptional adaptation from aerobiosis to hypoxia implicating ROX1 and IXR1 cross-regulation.

  2009cites this paper
• Iron Regulation through the Back Door: Iron-Dependent Metabolite Levels Contribute to Transcriptional Adaptation to Iron Deprivation in Saccharomyces cerevisiae

  2009cites this paper
• Metabolismo fermentativo nel lievito Kluyveromyces lactis : regolazione ossigeno-dipendente e autoregolazione del gene KlPDC1

  2009cites this paper
• Effects of the S288c genetic background and common auxotrophic markers on mitochondrial DNA function in Saccharomyces cerevisiae

  2008cites this paper
• Heme Levels Switch the Function of Hap1 of Saccharomyces cerevisiae between Transcriptional Activator and Transcriptional Repressor

  2007influential citation
• A functional analysis of KlSRB10: implications in Kluyveromyces lactis transcriptional regulation

  2007cites this paper
• An approach to the hypoxic and oxidative stress responses in Kluyveromyces lactis by analysis of mRNA levels.

  2007cites this paper
• Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: a genome‐wide study

  2007cites this paper
• Functional characterization of KlHAP1: a model to foresee different mechanisms of transcriptional regulation by Hap1p in yeasts.

  2007cites this paper
• Functional motifs outside the kinase domain of yeast Srb10p. Their role in transcriptional regulation and protein-interactions with Tup1p and Srb11p.

  2007cites this paper
• Regulation of long chain unsaturated fatty acid synthesis in yeast.

  2007cites this paper
• CONSERVED STRUCTURE-FUNCTION RELATIONSHIPS IN THE MEDIATOR COMPLEX

  2007cites this paper
• Med19(Rox3) Regulates Intermodule Interactions in the Saccharomyces cerevisiae Mediator Complex*

  2007cites this paper
• The Ccr4-Not Complex Regulates Skn7 through Srb10 Kinase

  2007cites this paper
• Physiological impact and context dependency of transcriptional responses: A chemostat study in Saccharomyces cerevisiae

  2007cites this paper
• Role of Heme in the Antifungal Activity of the Azaoxoaporphine Alkaloid Sampangine

  2007cites this paper
• A transcriptome analysis of Kluyveromyces lactis growing in cheese whey

  2006cites this paper
• Metabolic-State-Dependent Remodeling of the Transcriptome in Response to Anoxia and Subsequent Reoxygenation in Saccharomyces cerevisiae

  2006cites this paper
• The Ccr 4-Not Complex Regulates Skn 7 through Srb 10 Kinase

  2006cites this paper
• Recruitment of Tup1p and Cti6p regulates heme‐deficient expression of Aft1p target genes

  2006cites this paper
• Transcriptional response of Candida albicans to hypoxia: linkage of oxygen sensing and Efg1p-regulatory networks.

  2006cites this paper
• Systematic interpretation of microarray data using experiment annotations

  2006cites this paper
• An equilibrium partitioning model connecting gene expression and cis-motif content

  2006cites this paper
• Supplement to: Systematic interpretation of microarray data using experiment annotations

  2006cites this paper
• Large-scale analysis of genes that alter sensitivity to the anti-cancer drug tirapazamine in Saccharomyces cerevisiae.

  2005cites this paper
• Large-Scale Analysis of Genes that Alter Sensitivity to the Anticancer Drug Tirapazamine in Saccharomyces cerevisiaes⃞

  2005cites this paper
• Two-dimensional Transcriptome Analysis in Chemostat Cultures

  2005cites this paper
• Dynamical Remodeling of the Transcriptome during Short-Term Anaerobiosis in Saccharomyces cerevisiae: Differential Response and Role of Msn2 and/or Msn4 and Other Factors in Galactose and Glucose Media

  2005influential citation
• A hap1 mutation in a laboratory strain of Saccharomyces cerevisiae results in decreased expression of ergosterol-related genes and cellular ergosterol content compared to sake yeast.

  2004cites this paper
• Promoter-dependent roles for the Srb10 cyclin-dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae.

  2004cites this paper
• Experimental strategies for analyzing oxygen sensing in yeast.

  2004cites this paper
• The KlSRB10 gene from Kluyveromyces lactis

  2004cites this paper
• Genome-wide analysis of Kluyveromyces lactis in wild-type and rag2 mutant strains.

  2004cites this paper
• Analysis of the hypoxia‐induced ADH2 promoter of the respiratory yeast Pichia stipitis reveals a new mechanism for sensing of oxygen limitation in yeast

  2003cites this paper
• Inhibition of Heme Biosynthesis Prevents Transcription of Iron Uptake Genes in Yeast*

  2003cites this paper
• The Cyclin in the RNA Polymerase Holoenzyme Is a Target for the Transcriptional Repressor Tup1p in Saccharomyces cerevisiae

  2003influential citation
• A study of the yeast cell wall composition and structure in response to growth conditions and mode of cultivation

  2003cites this paper
• Investigating hypoxic tumor physiology through gene expression patterns

  2003cites this paper
• Current awareness on yeast.

  2002cites this paper
• Current Awareness on Comparative and Functional Genomics

  2002cites this paper