Salt-Sensitive Hypertension and Cardiac Hypertrophy in Transgenic Mice Expressing a Corin Variant Identified in Blacks

No abstract is available for this paper.

• Publication year

  2012

• Venue

  HYPERTENSION

• Publication date

  2012-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/HYPERTENSIONAHA.112.201244PMID 22987923PMCID PMC3475733
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy

  2012influential reference
• Rare, Nonsynonymous Variant in the Smooth Muscle-Specific Isoform of Myosin Heavy Chain, MYH11, R247C, Alters Force Generation in the Aorta and Phenotype of Smooth Muscle Cells

  2012cited by this paper
• Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice

  2012cited by this paper
• Decompensated Heart Failure Is Associated With Reduced Corin Levels and Decreased Cleavage of Pro–Atrial Natriuretic Peptide

  2011cited by this paper
• Corin-deficient W-sh mice poorly tolerate increased cardiac afterload.

  2011cited by this paper
• Human Corin Isoforms with Different Cytoplasmic Tails That Alter Cell Surface Targeting*

  2011cited by this paper
• Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases.

  2010cited by this paper
• Protease corin expression and activity in failing hearts.

  2010cited by this paper
• Plasma Soluble Corin in Patients With Heart Failure

  2010cited by this paper
• Abstract 18126: Ectodomain Shedding and Autocleavage of the Cardiac Membrane Protease Corin

  2010cited by this paper
• Corin: an ANP protease that may regulate sodium reabsorption in nephrotic syndrome.

  2010cited by this paper
• Corin: new insights into the natriuretic peptide system.

  2009cited by this paper
• Dysfunctional Corin I555(P568) Allele Is Associated With Impaired Brain Natriuretic Peptide Processing and Adverse Outcomes in Blacks With Systolic Heart Failure: Results From the Genetic Risk Assessment in Heart Failure Substudy

  2009cited by this paper
• Abstract 1760: Corin Variant Associated with Hypertension and Cardiac Hypertrophy Exhibits Impaired Zymogen Activation and Natriuretic Peptide Processing Activity

  2008cited by this paper
• Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.

  2008cited by this paper
• Role of Glycosylation in Corin Zymogen Activation*

  2007cited by this paper
• Corin I555(P568) Allele Is Associated With Enhanced Cardiac Hypertrophic Response to Increased Systemic Afterload

  2007cited by this paper
• The serine protease corin in cardiovascular biology and disease.

  2007cited by this paper
• Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension.

  2006cited by this paper
• Meta-analysis of genome-wide scans for blood pressure in African American and Nigerian samples. The National Heart, Lung, and Blood Institute GeneLink Project.

  2006cited by this paper
• Admixture mapping for hypertension loci with genome-scan markers

  2005cited by this paper
• Corin Gene Minor Allele Defined by 2 Missense Mutations Is Common in Blacks and Associated With High Blood Pressure and Hypertension

  2005influential reference
• Improvement in Blood Pressure With Inhibition of the Epithelial Sodium Channel in Blacks With Hypertension

  2005cited by this paper
• Serine proteases and cardiac function.

  2005cited by this paper
• Hypertension in mice lacking the proatrial natriuretic peptide convertase corin.

  2005influential reference
• Trends in prevalence, awareness, treatment and control of hypertension in the middle-aged population of China, 1992-1998.

  2004cited by this paper
• Multiple Polymorphisms in the Renin- Angiotensin-Aldosterone System (ACE, CYP11B2, AGTR1) and Their Contribution to Hypertension in African Americans and Latinos in the Multiethnic Cohort

  2004cited by this paper
• The Burden of Adult Hypertension in the United States 1999 to 2000: A Rising Tide

  2004cited by this paper
• The natriuretic peptides

  2004cited by this paper
• Upregulation of corin gene expression in hypertrophic cardiomyocytes and failing myocardium.

  2004cited by this paper
• Sodium retention in black and white female adolescents in response to salt intake.

  2004cited by this paper
• Association of polymorphisms in the promoter region of the PNMT gene with essential hypertension in African Americans but not in whites.

  2003cited by this paper
• Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000.

  2003cited by this paper
• Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A.

  2003cited by this paper
• Genomic Structures of the Human and Murine Corin Genes and Functional GATA Elements in Their Promoters*

  2002cited by this paper
• Racial Difference in the Activity of the Amiloride-Sensitive Epithelial Sodium Channel

  2002cited by this paper
• Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice.

  2001cited by this paper
• Functional deletion mutation of the 5'-flanking region of type A human natriuretic peptide receptor gene and its association with essential hypertension and left ventricular hypertrophy in the Japanese.

  2000cited by this paper
• Remodeling the cardiac sarcomere using transgenesis.

  2000cited by this paper
• Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme.

  2000cited by this paper
• Corin, a Mosaic Transmembrane Serine Protease Encoded by a Novel cDNA from Human Heart*

  1999cited by this paper
• Salt-sensitive hypertension in ANP knockout mice: potential role of abnormal plasma renin activity.

  1998cited by this paper
• Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts.

  1998cited by this paper
• Natriuretic peptides.

  1998cited by this paper
• Salt-sensitive hypertension in ANP knockout mice: potential role of abnormal plasma renin activity.

  1998cited by this paper
• Why is salt-sensitive hypertension so common in blacks?

  1997cited by this paper
• Polymorphisms of renin-angiotensin genes among Nigerians, Jamaicans, and African Americans.

  1996cited by this paper

• Beyond Natriuretic Peptides: Corin and Furin As Phenotype-Specific Biomarkers and Therapeutic Gatekeepers in Heart Failure

  2025cites this paper
• Corin in cardiovascular diseases and stroke.

  2025cites this paper
• Corin protects against acute kidney injury in mice through anti-inflammatory effects.

  2024cites this paper
• Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

  2024cites this paper
• Early- to Mid-gestational Testosterone Excess Leads to Adverse Cardiac Outcomes in Postpartum Sheep.

  2024cites this paper
• Corin deficiency alleviates mucosal lesions in a mouse model of colitis induced by dextran sulfate sodium.

  2024cites this paper
• Impact of adverse gestational milieu on maternal cardiovascular health.

  2023cites this paper
• Corin deficiency impairs cardiac function in mouse models of heart failure

  2023cites this paper
• Corin Deficiency Diminishes Intestinal Sodium Excretion in Mice

  2023cites this paper
• Association between salt sensitivity and blood pressure variability in patients with essential hypertension and predictive value for cardiovascular events

  2023cites this paper
• Corin: A Key Mediator in Sodium Homeostasis, Vascular Remodeling, and Heart Failure

  2022cites this paper
• Corin—The Early Marker of Preeclampsia in Pregestational Diabetes Mellitus

  2022cites this paper
• Soluble Corin Predicts the Risk of Cardiovascular Disease

  2022influential citation
• A Single Nucleotide Polymorphism in SH2B3/LNK Promotes Hypertension Development and Renal Damage

  2022cites this paper
• Edema formation in congestive heart failure and the underlying mechanisms

  2022cites this paper
• Association between CORIN methylation and hypertension in Chinese adults

  2022cites this paper
• Corin Deficiency Alters Adipose Tissue Phenotype and Impairs Thermogenesis in Mice

  2022cites this paper
• Corin Missense Variants, Blood Pressure, and Hypertension in 11 322 Black Individuals: Insights From REGARDS and the Jackson Heart Study

  2022cites this paper
• Change of cardiovascular risk associated serologic biomarkers after gastric bypass: A comparison of diabetic and non-diabetic Asian patients.

  2022cites this paper
• Associations of corin genetic polymorphisms with salt sensitivity, blood pressure changes, and hypertension incidence in Chinese adults

  2021cites this paper
• Recombinant Soluble Corin Improves Cardiac Function in Mouse Models of Heart Failure

  2021cites this paper
• A common CORIN variant in hypertension reduces corin intracellular trafficking by exposing an inhibitory N-terminus.

  2020cites this paper
• Hepsin: a multifunctional transmembrane serine protease in pathobiology

  2020cites this paper
• Function and regulation of corin in physiology and disease.

  2020cites this paper
• Understanding the Complexity of Heart Failure Risk and Treatment in Black Patients

  2020cites this paper
• Negligible Effect of Sodium Chloride on the Development and Function of TGF-β-Induced CD4+ Foxp3+ Regulatory T Cells

  2019cites this paper
• Pregnancy-Associated Cardiac Hypertrophy in Corin-Deficient Mice: Observations in a Transgenic Model of Preeclampsia.

  2019cites this paper
• Ectopic expression of human airway trypsin‐like protease 4 in acute myeloid leukemia promotes cancer cell invasion and tumor growth

  2019cites this paper
• Cross-linking, Immunoprecipitation and Proteomic Analysis to Identify Interacting Proteins in Cultured Cells

  2019cites this paper
• Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells.

  2019cites this paper
• Functional analysis of corin protein domains required for PCSK6-mediated activation.

  2018cites this paper
• TRPV4 (Transient Receptor Potential Vanilloid 4) Mediates Endothelium-Dependent Contractions in the Aortas of Hypertensive Mice

  2018cites this paper
• Association of rs2271037 and rs3749585 polymorphisms in CORIN with susceptibility to hypertension in a Chinese Han population: A case-control study.

  2018cites this paper
• Role of the protease corin in chondrogenic differentiation of human bone marrow‐derived mesenchymal stem cells

  2018cites this paper
• Corin is a key regulator of endochondral ossification and bone development via modulation of vascular endothelial growth factor A expression

  2018cites this paper
• Corin is highly expressed in atherosclerosis models.

  2018cites this paper
• Circulating soluble corin as a potential biomarker for cardiovascular diseases: A translational review.

  2018cites this paper
• TRPV4 activates cytosolic phospholipase A2 via Ca2+‐dependent PKC/ERK1/2 signalling in controlling hypertensive contraction

  2018cites this paper
• Pharmacogenomics of the Natriuretic Peptide System in Heart Failure

  2017cites this paper
• A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure

  2017cites this paper
• Treatment of hypertension by increasing impaired endothelial TRPV4‐KCa2.3 interaction

  2017cites this paper
• The Hypertension Pandemic: An Evolutionary Perspective.

  2017cites this paper
• Salt Sensitivity of Blood Pressure: A Scientific Statement From the American Heart Association.

  2016cites this paper
• Role of corin in the regulation of blood pressure

  2016cites this paper
• Study the correlation between plasma soluble corin and hypertention in ischemic heart disease in male patients

  2015cites this paper
• Longitudinal changes in maternal corin and mid‐regional proatrial natriuretic peptide in women at risk of pre‐eclampsia

  2015cites this paper
• Natriuretic Peptides and Cardiometabolic Health.

  2015cites this paper
• Atrial natriuretic peptide in cardiovascular biology and disease (NPPA).

  2015cites this paper
• Natriuretic Peptide and Cardiovascular Risk: Is It About “U”?

  2015cites this paper
• Corin is down-regulated and exerts cardioprotective action via activating pro-atrial natriuretic peptide pathway in diabetic cardiomyopathy

  2015cites this paper
• High sodium causes hypertension: evidence from clinical trials and animal experiments.

  2015cites this paper
• Racial Differences in Natriuretic Peptide Levels: The Dallas Heart Study.

  2015cites this paper
• Racial Differences in Circulating Natriuretic Peptide Levels: The Atherosclerosis Risk in Communities Study

  2015cites this paper
• PCSK6-mediated corin activation is essential for normal blood pressure

  2015cites this paper
• Epithelial sodium transport and its control by aldosterone: the story of our internal environment revisited.

  2015cites this paper
• Corin in Natriuretic Peptide Processing and Hypertension

  2014cites this paper
• A Corin Variant Identified in Hypertensive Patients That Alters Cytoplasmic Tail and Reduces Cell Surface Expression and Activity

  2014cites this paper
• Reduced urinary corin levels in patients with chronic kidney disease.

  2013cites this paper
• Role of corin and atrial natriuretic peptide in preeclampsia.

  2013cites this paper
• Corin: a new player in the regulation of salt–water balance and blood pressure

  2013cites this paper
• Corin Mutation R539C from Hypertensive Patients Impairs Zymogen Activation and Generates an Inactive Alternative Ectodomain Fragment*

  2013cites this paper