Neuroprotective effects of acetyl-L-carnitine after stroke in rats.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Annals of Emergency Medicine

• Publication date

  1997-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0196-0644(97)70197-5PMID 9174521
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Acetyl-L-carnitine attenuates neuronal damage in gerbils with transient forebrain ischemia only when given before the insult.

  1995cited by this paper
• Effects of L-carnitine on serum triglyceride and cytokine levels in rat models of cachexia and septic shock.

  1995cited by this paper
• Anti-intercellular adhesion molecule-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the Wistar rat.

  1995cited by this paper
• Malnutrition in stroke patients on the rehabilitation service and at follow-up: prevalence and predictors.

  1995cited by this paper
• YM796, a novel muscarinic agonist, improves the impairment of learning behavior in a rat model of chronic focal cerebral ischemia.

  1995cited by this paper
• Chronic depression of glucose metabolism in postischemic rat brains.

  1995cited by this paper
• Effects of RGH-2202 on behavioral deficits after focal cerebral ischemia in rats.

  1995cited by this paper
• Neuroprotection With a Calpain Inhibitor in a Model of Focal Cerebral Ischemia

  1994cited by this paper
• Postischemic Administration of an Anti‐Mac‐1 Antibody Reduces Ischemic Cell Damage After Transient Middle Cerebral Artery Occlusion in Rats

  1994cited by this paper
• Feeding dependence and nutritional status after acute stroke.

  1994cited by this paper
• Stroke: early pathophysiology and treatment. Summary of the Fifth Annual Decade of the Brain Symposium.

  1994cited by this paper
• Stability of Thrombosis Induced by Electrocoagulation of Rat Middle Cerebral Artery

  1994cited by this paper
• Stroke disability.

  1994cited by this paper
• Postischemic inhibition of cerebral cortex pyruvate dehydrogenase.

  1994cited by this paper
• Spontaneous reperfusion of cerebral infarcts in patients with acute stroke. Incidence, time course, and clinical outcome in the Copenhagen Stroke Study.

  1994cited by this paper
• Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha.

  1994cited by this paper
• Neuroprotective activity of acetyl‐L‐carnitine: Studies in vitro

  1994cited by this paper
• Anti‐CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat

  1994cited by this paper
• Effect of acetyl-L-carnitine on recovery of brain phosphorus metabolites and lactic acid level during reperfusion after cerebral ischemia in the rat--study by 13P- and 1H-NMR spectroscopy.

  1994cited by this paper
• Anatomic Variation of the Middle Cerebral Artery in the Sprague‐Dawley Rat

  1993cited by this paper
• Mechanism of muscle protein degradation in cancer cachexia.

  1993cited by this paper
• Effect of riluzole on focal cerebral ischemia in rats.

  1993cited by this paper
• Inhibition of postcardiac arrest brain protein oxidation by acetyl-L-carnitine.

  1993cited by this paper
• Prevention of Postischemic Canine Neurological Injury Through Potentiation of Brain Energy Metabolism by Acetyl‐L‐Carnitine

  1992cited by this paper
• Focal and Perifocal Changes in Tissue Energy State during Middle Cerebral Artery Occlusion in Normo- and Hyperglycemic Rats

  1992cited by this paper
• Neurological and Behavioral Outcomes of Focal Cerebral Ischemia in Rats

  1992cited by this paper
• The effect of the NMDA receptor antagonist MK-801 on cerebral blood flow and infarct volume in experimental focal stroke.

  1992cited by this paper
• Dexmedetomidine improves neurologic outcome from incomplete ischemia in the rat. Reversal by the alpha 2-adrenergic antagonist atipamezole.

  1991cited by this paper
• Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy.

  1990cited by this paper
• Local as well as remote functional and metabolic changes after focal ischemia in cats.

  1990cited by this paper
• Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury.

  1989cited by this paper
• Oxidants and the central nervous system: some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke?

  1989cited by this paper
• Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries

  1988cited by this paper
• Cancer cachexia.

  1988cited by this paper
• Brain calcium content in ischemic infarction

  1987cited by this paper
• Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

  1986cited by this paper
• A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction.

  1986cited by this paper
• Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats.

  1986cited by this paper
• Mitochondrial damage during cerebral ischemia.

  1985cited by this paper

• Longitudinal Brain Structural, Neurochemical, and Behavioral Changes Following Traumatic Brain Injury in Immature Rat Brain with ALCAR Treatment

  2025cites this paper
• Veterinary medical care in rodent models of stroke: Pitfalls and refinements to balance quality of science and animal welfare.

  2025cites this paper
• L-carnitine reduces acute lung injury via mitochondria modulation and inflammation control in pulmonary macrophages

  2023cites this paper
• Metabolomics and Lipidomics of Ischemic Stroke.

  2018cites this paper
• Exploration of the Fecal Microbiota and Biomarker Discovery in Equine Grass Sickness.

  2018cites this paper
• Interplay between mitochondrial metabolism and oxidative stress in ischemic stroke: An epigenetic connection.

  2017cites this paper
• Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments

  2017cites this paper
• Pyruvate dehydrogenase complex in cerebral ischemia-reperfusion injury

  2016cites this paper
• Potential protective effects of l-carnitine against neuromuscular ischemia-reperfusion injury: From experimental data to potential clinical applications.

  2016cites this paper
• “Boomerang Neuropathology” of Late-Onset Alzheimer’s Disease is Shrouded in Harmful “BDDS”: Breathing, Diet, Drinking, and Sleep During Aging

  2015cites this paper
• System-wide assembly of pathways and modules hierarchically reveal metabolic mechanism of cerebral ischemia

  2015cites this paper
• L-Carnitine Enhances Axonal Plasticity and Improves White-Matter Lesions after Chronic Hypoperfusion in Rat Brain

  2015cites this paper
• Fish Oil Diet Associated with Acute Reperfusion Related Hemorrhage, and with Reduced Stroke-Related Sickness Behaviors and Motor Impairment

  2014cites this paper
• Modulation of neuronal activity and hepatic metabolism by ploidy and l-carnitine supplement in rainbow trout (Oncorhynchus mykiss)

  2014cites this paper
• Augmentation of Normal and Glutamate-Impaired Neuronal Respiratory Capacity by Exogenous Alternative Biofuels

  2013cites this paper
• Reduction of Brain Mitochondrial β-Oxidation Impairs Complex I and V in Chronic Alcohol Intake: The Underlying Mechanism for Neurodegeneration

  2013cites this paper
• Protective effects of acetyl-L-carnitine on neurodegenarative changes in chronic cerebral ischemia models and learning-memory impairment in aged rats

  2012cites this paper
• Metabolic Agents that Enhance ATP can Improve Cognitive Functioning: A Review of the Evidence for Glucose, Oxygen, Pyruvate, Creatine, and L-Carnitine

  2011cites this paper
• Neuroprotection by Acetyl-L-Carnitine after Traumatic Injury to the Immature Rat Brain

  2011cites this paper
• Inhibitory effects of alcohol on glucose transport across the blood–brain barrier leads to neurodegeneration: preventive role of acetyl-l-carnitine

  2011cites this paper
• Acetyl-L-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain.

  2010cites this paper
• Acetyl‐l‐carnitine reduces the infarct size and striatal glutamate outflow following focal cerebral ischemia in rats

  2010cites this paper
• Metabolism of acetyl‐l‐carnitine for energy and neurotransmitter synthesis in the immature rat brain

  2010cites this paper
• Mitochondrial mechanisms of cell death and neuroprotection in pediatric ischemic and traumatic brain injury.

  2009cites this paper
• Hypoxic-Ischemic Brain Damage

  2009cites this paper
• Acetyl-L-Carnitine selectively prevents post-ischemic LTP via a possible action on mitochondrial energy metabolism.

  2008cites this paper
• Acetyl-L-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine.

  2006cites this paper
• Could nutraceuticals be a further weapon in the battle for weight loss

  2006cites this paper
• CARNITINE ESTERS PREVENT OXIDATIVE STRESS DAMAGE AND ENERGY DEPLETION FOLLOWING TRANSIENT FOREBRAIN ISCHAEMIA IN THE RAT HIPPOCAMPUS

  2006cites this paper
• Beneficial effects and side effects of DHEA: true anti-aging and age-promoting effects, as well as anti-cancer and cancer-promoting effects of DHEA evaluated from the effects on the normal and cancer cell telomeres and other parameters.

  2005cites this paper
• Beneficial Effects & Side Effects of DHEA: True Anti-Aging & Age-Promoting Effects, as well as Anti-Cancer & Cancer-Promoting Effects of DHEA Evaluated From the Effects on the Normal & Cancer Cell Telomeres & Other Parameters

  2005cites this paper
• Delayed therapy of experimental global cerebral ischemia with acetyl-L-carnitine in dogs.

  2005cites this paper
• L-carnitine protects against glutamate- and kainic acid-induced neurotoxicity in cerebellar granular cell culture of rats.

  2005cites this paper
• Mechanisms of Ischemic Neuroprotection by Acetyl‐l‐carnitine

  2005cites this paper
• Metabolic stages, mitochondria and calcium in hypoxic/ischemic brain damage.

  2004cites this paper
• Astrocyte Mitochondrial Mechanisms of Ischemic Brain Injury and Neuroprotection

  2004cites this paper
• L-Carnitine Reduces Brain Injury after Hypoxia-Ischemia in Newborn Rats

  2003cites this paper
• Neuroprotective effects of hyperbaric oxygen treatment in experimental focal cerebral ischemia are associated with reduced brain leukocyte myeloperoxidase activity.

  2003cites this paper
• Protective role of carnitine esters against alcohol-induced gastric lesions in rats.

  2003cites this paper
• Acetyl-L-Carnitine: Biological Properties and Clinical Application (A Review)

  2002cites this paper
• Brain Regions Involved in Fatigue Sensation: Reduced Acetylcarnitine Uptake into the Brain

  2002cites this paper
• L-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice.

  2002cites this paper
• Anti-apoptotic effect of acetyl-l-carnitine and I-carnitine in primary cultured neurons.

  2000cites this paper
• Neuronal subclass-selective loss of pyruvate dehydrogenase immunoreactivity following canine cardiac arrest and resuscitation.

  2000cites this paper
• BN 80933, a dual inhibitor of neuronal nitric oxide synthase and lipid peroxidation: a promising neuroprotective strategy.

  1999cites this paper
• Neuroprotective effect of L-lysine monohydrochloride on acute iterative anoxia in rats with quantitative analysis of electrocorticogram.

  1999cites this paper
• Attenuation by acetyl-L-carnitine of neurological damage and biochemical derangement following brain ischemia and reperfusion.

  1999cites this paper
• Neurodegeneration and Aging of the Central Nervous System

  1998cites this paper
• Protective effects of free radical inhibitors in intracerebral hemorrhage in rat.

  1998cites this paper