Contribution of G inhibitory protein alpha subunits in paradoxical hyperalgesia elicited by exceedingly low doses of morphine in mice.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Life Science

• Publication date

  2011-12-19

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.lfs.2011.09.025PMID 22008476
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Supraspinal Gβγ‐dependent stimulation of PLCβ3 originating from G inhibitory protein‐μ opioid receptor‐coupling is necessary for morphine induced acute hyperalgesia

  2009cited by this paper
• Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study.

  2006cited by this paper
• Signaling pathway of morphine induced acute thermal hyperalgesia in mice

  2006cited by this paper
• Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor-G protein coupling and Gbetagamma signaling.

  2005cited by this paper
• Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor–G protein coupling and Gβγ signaling

  2005cited by this paper
• Roles of alpha1- and alpha2-adrenoceptors in the nucleus raphe magnus in opioid analgesia and opioid abstinence-induced hyperalgesia.

  2003cited by this paper
• Roles of α1- and α2-Adrenoceptors in the Nucleus Raphe Magnus in Opioid Analgesia and Opioid Abstinence-Induced Hyperalgesia

  2003cited by this paper
• Role of Gi Proteins in the Antidepressant-like Effect of Amitriptyline and Clomipramine

  2002cited by this paper
• Stimulation of peripheral nociceptor endings by low dose morphine and its signaling mechanism.

  2002cited by this paper
• In vivo modulation of G proteins and opioid receptor function by antisense oligodeoxynucleotides.

  2000cited by this paper
• Acute Opioid Tolerance: Intraoperative Remifentanil Increases Postoperative Pain and Morphine Requirement

  2000cited by this paper
• Potentiation of transmitter release from NMB human neuroblastoma cells by kappa-opioids is mediated by N-type voltage-dependent calcium channels.

  1999cited by this paper
• Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GM1 ganglioside-regulated opioid receptor functions.

  1998cited by this paper
• delta Opioid receptor subtypes activate inositol-signaling pathways in the production of antinociception.

  1998cited by this paper
• Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits.

  1996cited by this paper
• The stimulatory effects of opioids and their possible role in the development of tolerance.

  1996cited by this paper
• Cloning and functional characterization through antisense mapping of a kappa 3-related opioid receptor.

  1995cited by this paper
• Activation of Type II Adenylyl Cyclase by the Cloned μ‐Opioid Receptor: Coupling to Multiple G Proteins

  1995cited by this paper
• Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma x glioma hybrid NG108-15 cells.

  1992cited by this paper
• The increasing-temperature hot-plate test: an improved test of nociception in mice and rats.

  1991cited by this paper
• Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.

  1991cited by this paper
• Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons.

  1990cited by this paper
• 5‐Hydroxytryptamine acts at 5‐HT2 receptors to decrease potassium conductance in rat nucleus accumbens neurones.

  1989cited by this paper
• Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture.

  1989cited by this paper
• Paradoxical hyperalgesic effect of exceedingly low doses of systemic morphine in an animal model of persistent pain (Freund's adjuvant-induced arthritic rats).

  1987cited by this paper
• The stress of a novel environment reduces formalin pain: possible role of serotonin.

  1986cited by this paper
• A comparison of the antinociceptive responses to the GABA-receptor agonists THIP and baclofen.

  1985cited by this paper
• Placebo and naloxone can alter post-surgical pain by separate mechanisms

  1983influential reference
• Intrathecal high dose morphine produces hyperalgesia in the rat.

  1981influential reference
• The narcotic antagonist naloxone enhances clinical pain

  1978influential reference
• Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure.

  1975influential reference
• Morphine Action at Central Nervous System Sites in Rat: Analgesia or Hyperalgesia Depending on Site and Dose

  1973influential reference
• Morphine-induced hyperalgesia in rats tested on the hot plate.

  1971influential reference
• The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation.

  1962cited by this paper
• Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse.

  1957influential reference
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Opioid-induced hyperalgesia: Cellular and molecular mechanisms.

  2016cites this paper
• Mas-Related Gene (Mrg) C Activation Attenuates Bone Cancer Pain via Modulating Gi and NR2B

  2016cites this paper
• Differential contribution of Gαi/o subunits in the response to food deprivation.

  2015cites this paper
• Inhibition of spinal ERK1/2-c-JUN signaling pathway counteracts the development of low doses morphine-induced hyperalgesia.

  2015cites this paper
• Regionally selective activation of ERK and JNK in morphine paradoxical hyperalgesia: a step toward improving opioid pain therapy.

  2014cites this paper
• Endogenous opiates and behavior: 2011.

  2012cites this paper
• What Do We Know About Opioid-Induced Hyperalgesia ?

  year unknowncites this paper