The probiotic Escherichia coli strain Nissle 1917 induces gammadelta T cell apoptosis via caspase- and FasL-dependent pathways.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  International Immunology

• Publication date

  2008-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/intimm/dxn041PMID 18448456
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Fas-Associated Death Domain Protein Is Required in Apoptosis and TLR-Induced Proliferative Responses in B Cells1

  2006cited by this paper
• Analysis of cycloheximide‐induced apoptosis in human leukocytes: Fluorescence microscopy using annexin V/propidium iodide versus acridin orange/ethidium bromide

  2006cited by this paper
• The function of gammadelta T cells in innate immunity.

  2006cited by this paper
• Escherichia coli Strain Nissle 1917 Ameliorates Experimental Colitis via Toll-Like Receptor 2- and Toll-Like Receptor 4-Dependent Pathways

  2006cited by this paper
• The function of γδ T cells in innate immunity

  2006cited by this paper
• Antibiotics for inflammatory bowel disease: do they work?

  2005cited by this paper
• Escherichia coli Nissle 1917 Distinctively Modulates T-Cell Cycling and Expansion via Toll-Like Receptor 2 Signaling

  2005influential reference
• Probiotic Therapy in the Prevention of Pouchitis Onset: Decreased Interleukin‐1&bgr;, Interleukin‐8, and Interferon‐&ggr; Gene Expression

  2005cited by this paper
• Genomic peculiarity of coding sequences and metabolic potential of probiotic Escherichia coli strain Nissle 1917 inferred from raw genome data.

  2005cited by this paper
• Professional antigen-presentation function by human gammadelta T Cells.

  2005cited by this paper
• Probiotic therapy in the prevention of pouchitis onset: decreased interleukin-1beta, interleukin-8, and interferon-gamma gene expression.

  2005cited by this paper
• Infliximab for induction and maintenance therapy for ulcerative colitis.

  2005cited by this paper
• Caspases: pharmacological manipulation of cell death.

  2005cited by this paper
• Molecular mechanisms of TNF-alpha-induced apoptosis in aging human T cell subsets.

  2005cited by this paper
• Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn’s disease: a randomised, double blind, placebo controlled GETAID trial

  2005cited by this paper
• Molecular mechanisms of TNF-α-induced apoptosis in aging human T cell subsets

  2005cited by this paper
• Genetic basis for increased intestinal permeability in families with Crohn’s disease: role of CARD15 3020insC mutation?

  2005cited by this paper
• gammadelta T cells link innate and adaptive immune responses.

  2005cited by this paper
• Professional Antigen-Presentation Function by Human γδ T Cells

  2005cited by this paper
• Analysis of the Genome Structure of the Nonpathogenic Probiotic Escherichia coli Strain Nissle 1917

  2004cited by this paper
• Preventive Effects of Escherichia coli Strain Nissle 1917 on Acute and Chronic Intestinal Inflammation in Two Different Murine Models of Colitis

  2004cited by this paper
• Inflammatory bowel disease: the role of environmental factors.

  2004cited by this paper
• Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics.

  2004cited by this paper
• Antibiotics and probiotics in inflammatory bowel disease

  2004cited by this paper
• Human Galectin-2: Novel Inducer of T Cell Apoptosis with Distinct Profile of Caspase Activation1

  2004cited by this paper
• Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine

  2004cited by this paper
• CXCL8 modulates human intestinal epithelial cells through a CXCR1 dependent pathway.

  2004cited by this paper
• Optimizing anti-TNF treatment in inflammatory bowel disease.

  2004cited by this paper
• NF-κB- and AP-1-Mediated Induction of Human Beta Defensin-2 in Intestinal Epithelial Cells by Escherichia coli Nissle 1917: a Novel Effect of a Probiotic Bacterium

  2004cited by this paper
• Comparative measurement of spontaneous apoptosis in pediatric acute leukemia by different techniques

  2003cited by this paper
• Rationale for Probiotic and Antibiotic Treatment Strategies in Inflammatory Bowel Diseases

  2003cited by this paper
• Major histocompatibility lineages and immune gene function in teleost fishes: the road not taken.

  2003cited by this paper
• Development of strain-specific PCR reactions for the detection of the probiotic Escherichia coli strain Nissle 1917 in fecal samples.

  2003cited by this paper
• Compartmentalization gamma/delta T cells and their putative role in mucosal immunity.

  2003cited by this paper
• Messengers of cell death: apoptotic signaling in health and disease.

  2003cited by this paper
• Regulation of T cell apoptosis during the immune response.

  2002cited by this paper
• Probiotic Bacterium Prevents Cytokine-induced Apoptosis in Intestinal Epithelial Cells*

  2002cited by this paper
• Ineffectiveness of probiotics in preventing recurrence after curative resection for Crohn's disease: a randomised controlled trial with Lactobacillus GG

  2002cited by this paper
• A Single Nucleotide Exchange in the wzy Gene Is Responsible for the Semirough O6 Lipopolysaccharide Phenotype and Serum Sensitivity of Escherichia coli Strain Nissle 1917

  2002cited by this paper
• Treatment of mild to moderate ulcerative colitis and pouchitis

  2002cited by this paper
• Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial.

  2002cited by this paper
• p53 negatively regulates intestinal immunity by delaying mucosal T cell cycling.

  2002cited by this paper
• Interleukin-8 and human cancer biology.

  2001cited by this paper
• Maintenance of remission in ulcerative colitis is equally effective with Escherichia coli Nissle 1917 and with standard mesalamine

  2001cited by this paper
• A comparison of the methods applied to detect apoptosis in genotoxically-damaged lymphocytes cultured in the presence of four antimutagens.

  2001cited by this paper
• Antigen Recognition by Human γδ T Lymphocytes

  2000cited by this paper
• The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems.

  2000cited by this paper
• Simultaneous estimation of T(G2+M), T(S), and T(pot) using single sample dynamic tumor data from bivariate DNA-thymidine analogue cytometry.

  2000cited by this paper
• Proteases for Cell Suicide: Functions and Regulation of Caspases

  2000cited by this paper
• Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial.

  2000cited by this paper
• T cell life and death signalling via TNF-receptor family members.

  2000cited by this paper
• Cell-cycle regulation in immunity, tolerance and autoimmunity.

  2000cited by this paper
• Antigen recognition by human gammadelta T lymphocytes.

  2000cited by this paper
• CD95's deadly mission in the immune system

  2000cited by this paper
• T Cell Effector Function and Anergy Avoidance Are Quantitatively Linked to Cell Division1

  2000cited by this paper
• The biochemistry of apoptosis

  2000cited by this paper
• Tumour necrosis factor α and interleukin 1β in relapse of Crohn's disease

  1999cited by this paper
• Transforming Growth Factor β1 Inhibits Fas Ligand Expression and Subsequent Activation-induced Cell Death in T Cells via Downregulation of c-Myc

  1999cited by this paper
• Effector functions and control of human gammadelta T-cell activation.

  1999cited by this paper
• Instruction for Cytokine Expression in T Helper Lymphocytes in Relation to Proliferation and Cell Cycle Progression

  1999cited by this paper
• Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives.

  1999cited by this paper
• Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid.

  1999cited by this paper
• CDK inhibitors: positive and negative regulators of G1-phase progression.

  1999cited by this paper
• Peripheral T cell survival.

  1999cited by this paper
• Tumour necrosis factor alpha and interleukin 1beta in relapse of Crohn's disease.

  1999cited by this paper
• Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial.

  1999cited by this paper
• Effector functions and control of human γδ T-cell activation

  1999cited by this paper
• Death receptors: signaling and modulation.

  1998cited by this paper
• Cooperation of both TNF receptors in inducing apoptosis: involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75.

  1998cited by this paper
• Inflammatory bowel disease: etiology and pathogenesis.

  1998cited by this paper
• Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis.

  1998cited by this paper
• Helper T cell differentiation is controlled by the cell cycle.

  1998cited by this paper
• Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation.

  1998cited by this paper
• Double‐blind comparison of an oral Escherichia coli preparation and mesalazine in maintaining remission of ulcerative colitis

  1997cited by this paper
• Increased frequency of abnormal gamma delta T cells in blood of patients with inflammatory bowel diseases.

  1996cited by this paper
• Inhibitors of mammalian G1 cyclin-dependent kinases.

  1995cited by this paper
• Properties ofEscherichia coli strains of serotype O6

  1995cited by this paper
• Increase of circulating gamma/delta T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease.

  1994cited by this paper
• Increase of circulating γ/δ T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease

  1994cited by this paper
• G1 phase progression: cycling on cue.

  1994cited by this paper
• Reduction in apoptosis relative to mitosis in histologically normal epithelium accompanies fibrocystic change and carcinoma of the premenopausal human breast

  1992cited by this paper
• A method to measure the duration of DNA synthesis and the potential doubling time from a single sample.

  1985cited by this paper
• For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group

  year unknowncited by this paper

• γδ T Cells: Dual Function in Modulating Inflammation-Cancer Transition in Colorectal Carcinogenesis.

  2025cites this paper
• Transcriptional profiling of probiotic Escherichia coli Nissle 1917 under multiple environmental stresses: Simulated microgravity, microaerobic, and co-culture conditions.

  2025cites this paper
• Intestinal Luminal Anion Transporters and their Interplay with Gut Microbiome and Inflammation.

  2025cites this paper
• Serial passage in an insect host indicates genetic stability of the human probiotic Escherichia coli Nissle 1917

  2022cites this paper
• Effects of Escherichia coli Nissle 1917 on the Porcine Gut Microbiota, Intestinal Epithelium and Immune System in Early Life

  2022cites this paper
• An Escherichia coli strain with extra catalase activity protects against murine colitis by scavenging hydrogen peroxide and regulating regulatory t cell/interleukin-17 pathways.

  2021cites this paper
• Serial passage of the human probiotic E. coli Nissle 1917 in an insect host leads to changed bacterial phenotypes

  2021cites this paper
• Possible correlation between Lactobacillus paracasei X12 intake and tumor characteristics in the rat model of colorectal cancer

  2020cites this paper
• Intestinal effect of the probiotic Escherichia coli strain Nissle 1917 and its OMV

  2020cites this paper
• Anti-cancer properties of Escherichia coli Nissle 1917 against HT-29 colon cancer cells through regulation of Bax/Bcl-xL and AKT/PTEN signaling pathways

  2020cites this paper
• Transcriptional Profiling of the Probiotic Escherichia coli Nissle 1917 Strain under Simulated Microgravity

  2020cites this paper
• Substantial Extracellular Metabolic Differences Found Between Phylogenetically Closely Related Probiotic and Pathogenic Strains of Escherichia coli

  2019cites this paper
• Mechanisms Underlying the Beneficial Role of Probiotics in Diarrheal Diseases: Host–Microbe Interactions

  2018cites this paper
• The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice

  2018cites this paper
• Enterotoxigenic Escherichia coli infection promotes apoptosis in piglets.

  2018cites this paper
• E. coli Nissle 1917-Derived Minicells for Targeted Delivery of Chemotherapeutic Drug to Hypoxic Regions for Cancer Therapy

  2018cites this paper
• Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

  2017cites this paper
• Intestinal Anti-inflammatory Effects of Outer Membrane Vesicles from Escherichia coli Nissle 1917 in DSS-Experimental Colitis in Mice

  2017cites this paper
• Können Sie Probiotika empfehlen?

  2017cites this paper
• Human peripheral γδT cell phenotypic and functional shift in response to stimulation with E.coli

  2017cites this paper
• Escherichia coli Nissle 1917

  2017cites this paper
• Apical and basolateral IL-8, CXCL1 and miR-146a responses in human intestinal epithelial T84 and in monocytic THP-1 cells to probiotic E. coli Nissle 1917 and enteropathogenic E. coli

  2016cites this paper
• The role of inter-strain interactions on the growth, virulence and detection of Listeria monocytogenes

  2016cites this paper
• Disruption of Escherichia coli Nissle 1917 K5 Capsule Biosynthesis, through Loss of Distinct kfi genes, Modulates Interaction with Intestinal Epithelial Cells and Impact on Cell Health

  2015cites this paper
• Infection with respiratory syncytial virus influences FasL-mediated apoptosis of pulmonary γδ T cells in a murine model of allergen sensitization

  2014cites this paper
• Mechanistic Insight into the TH1-Biased Immune Response to Recombinant Subunit Vaccines Delivered by Probiotic Bacteria-Derived Outer Membrane Vesicles

  2014influential citation
• Microbiota biodiversity in inflammatory bowel disease

  2014cites this paper
• Intestinal dysbiosis: novel mechanisms by which gut microbes trigger and prevent disease.

  2014cites this paper
• Engineered Outer Membrane Vesicles Derived From Probiotic Escherichia Coli Nissle 1917 As Recobinant Subunit Antigen Carreirs For The Development Of Pathogen-Mimetic Vaccines

  2014cites this paper
• Probiotics as immunomodulators: substances, mechanisms and therapeutic benefits

  2013cites this paper
• Probiotics: properties, examples, and specific applications.

  2013cites this paper
• Culture supernatants from lactobacillus plantarum induce necrosis on a human promyelocytic leukemia cell line.

  2013cites this paper
• Relevance of Commensal Microbiota in the Treatment and Prevention of Inflammatory Bowel Disease

  2013cites this paper
• Probiotic bacteria reduce salmonella typhimurium intestinal colonization by competing for iron.

  2013cites this paper
• Quantifying the effects of high fructose feeding on the intestinal permeability of endotoxins

  2013cites this paper
• Spore-forming bacteria and their utilisation as probiotics.

  2012cites this paper
• Running Title : Engineered bacterium inhibits tumor growth 1 2 Title : Escherichia coli Nissle 1917 targets and restrains mouse B 16 melanoma and 4 T 1 breast 3 tumor through the expression of azurin protein

  2012cites this paper
• Probiotic-induced apoptosis and its potential relevance to mucosal inflammation of gastrointestinal tract.

  2012cites this paper
• Escherichia coli Nissle 1917 Targets and Restrains Mouse B16 Melanoma and 4T1 Breast Tumors through Expression of Azurin Protein

  2012cites this paper
• Development of γδ T cell subset responses in gnotobiotic pigs infected with human rotaviruses and colonized with probiotic lactobacilli.

  2011cites this paper
• Dextran Sodium Sulfate-Induced Inflammation Alters the Expression of Proteins by Intestinal Escherichia coli Strains in a Gnotobiotic Mouse Model

  2011cites this paper
• Probiotic factors partially improve parameters of 5-fluorouracil-induced intestinal mucositis in rats

  2011cites this paper
• Escherichia coli Nissle 1917 (Mutaflor): New Insights into an Old Probiotic Bacterium

  2011cites this paper
• Characterization of Avian γδ T-Cell Subsets after Salmonella enterica Serovar Typhimurium Infection of Chicks

  2010cites this paper
• Probiotic Escherichia coli Nissle 1917 activates DC and prevents house dust mite allergy through a TLR4‐dependent pathway

  2010cites this paper
• The K5 Capsule of Escherichia coli Strain Nissle 1917 Is Important in Stimulating Expression of Toll-Like Receptor 5, CD14, MyD88, and TRIF Together with the Induction of Interleukin-8 Expression via the Mitogen-Activated Protein Kinase Pathway in Epithelial Cells

  2010cites this paper
• Probiotics-host communication

  2010cites this paper
• Anti-infective mechanisms induced by a probiotic Lactobacillus strain against Salmonella enterica serovar Typhimurium infection.

  2010cites this paper
• The K5 Capsule of Escherichia coli Strain Nissle 1917 Is Important in Mediating Interactions with Intestinal Epithelial Cells and Chemokine Induction

  2009cites this paper
• Preferential promotion of apoptosis of monocytes by Lactobacillus casei rhamnosus soluble factors.

  2009cites this paper
• Split immune response after oral vaccination of mice with recombinant Escherichia coli Nissle 1917 expressing fimbrial adhesin K88.

  2009cites this paper
• Modulation der intestinalen Barriere - Signalwege und Wirkmechanismen von Escherichia coli Nissle 1917 und enteraler Ernährung

  2009cites this paper
• The non-pathogenic Escherichia coli strain Nissle 1917 – features of a versatile probiotic

  2009cites this paper
• Characterization of Escherichia coli colonizing the gastrointestinal tract and urinary tract catheters

  2008cites this paper
• Molecular pathogenesis of inflammatory bowel disease: relevance for novel therapies.

  2008cites this paper