Evaluation of the toxicity of enzymatically decomposed rutin with 13-weeks dietary administration to Wistar rats.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Food and Chemical Toxicology

• Publication date

  2004-03-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/J.FCT.2003.10.006PMID 14871585
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• 13-Week Oral Toxicity and 4-week Recovery Study of Enzymatically Modified Isoquercitrin in F344/DuCrj Rats

  2002cited by this paper
• Polyphenolic antioxidants from the fruits of Chrysophyllum cainito L. (Star Apple).

  2002cited by this paper
• Presence of aldose reductase inhibitors in tea leaves.

  2001cited by this paper
• Effect of plant growth temperature on antioxidant capacity in strawberry.

  2001cited by this paper
• Human Nutrition and Metabolism—Research Communication Bioavailabilities of Quercetin-3- Glucoside and Quercetin-4*- Glucoside Do Not Differ in Humans

  2000cited by this paper
• Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes.

  1998cited by this paper
• Antioxidant Activity of Different Phenolic Fractions Separated from an Italian Red Wine.

  1998cited by this paper
• Toxicity and carcinogenicity studies of quercetin, a natural component of foods.

  1992cited by this paper
• Lack of Carcinogenicity of Quercetin in F344/DuCrj Rats

  1989cited by this paper
• Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans.

  1987cited by this paper
• Tobacco constituents are mitogenic for arterial smooth-muscle cells.

  1985cited by this paper
• Genetic effects of the flavonols quercetin, kaempferol, and galangin on Chinese hamster ovary cells in vitro.

  1983cited by this paper
• Carcinogenicity test of quercetin and rutin in golden hamsters by oral administration.

  1982cited by this paper
• Mutagenicities of 61 flavonoids and 11 related compounds.

  1981cited by this paper
• Carcinogenicity examination of quercetin and rutin in ACI rats.

  1981cited by this paper
• Activity of the plant flavanol quercetin in the mouse lymphoma L5178Y TK+/- mutation, DNA single-strand break, and Balb/c 3T3 chemical transformation assays.

  1981cited by this paper
• A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds.

  1980cited by this paper
• -L-rhamnosidases of the liver of Turbo cornutus and Aspergillus niger.

  1973cited by this paper

• Isoquercitrin: From natural source to clinical candidate - Synthesis, pharmacology, and metabolic safety.

  2025cites this paper
• Fluorescent sensing of rutin by carbon dots derived from the heart of cumin seeds

  2024cites this paper
• Polyphenols of four medicinal plants extracts and relation with antifungal activities through in vitro and in silico studies

  2024cites this paper
• Isoquercitrin improves diabetes nephropathy by inhibiting the sodium-glucose co-transporter-2 pathway.

  2024cites this paper
• Evaluation of the toxicity of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb in in vitro and in vivo models.

  2023cites this paper
• Synergistic Effects of Heat-Treated Green Tea Extract and Enzymatically-Modified Isoquercitrin in Preventing Obesity

  2023cites this paper
• Dietary Isoquercetin Reduces Hepatic Cholesterol and Triglyceride in NAFLD Mice by Modulating Bile Acid Metabolism via Intestinal FXR-FGF15 Signaling.

  2023cites this paper
• Effects of rutin supplementation on growth performance, slaughter performance, serum parameters, and meat quality of Nubian goats.

  2023cites this paper
• Oral chronic toxicity and carcinogenicity study of alpha-glycosyl isoquercitrin (AGIQ) in Sprague Dawley rats.

  2023cites this paper
• Action of crude ethanol extract of Hymenaea martiana leaf, gallic acid, and polypyrrole (PPy) against Aeromonas hydrophila

  2023cites this paper
• Isoquercitrin attenuates the osteoclast-mediated bone loss in rheumatoid arthritis via the Nrf2/ROS/NF-κB pathway.

  2023cites this paper
• Rutin ameliorate PFOA induced renal damage by reducing oxidative stress and improving lipid metabolism.

  2023cites this paper
• Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.

  2023cites this paper
• Genotoxicity and mutagenicity evaluation of isoquercitrin-γ-cyclodextrin molecular inclusion complex using Ames test and a combined micronucleus and comet assay in rats.

  2022cites this paper
• Citrus Flavonoids: Biological Activities, Implementation in Skin Health, and Topical Applications: A Review

  2022cites this paper
• Production of isoquercitrin from quercetin by biotransformation using Bascillus sp. CSQ10 isolated from Camellia sinensis cultivation soils

  2022cites this paper
• Preparation of Isoquercetin From Toona sinensis by Liquid-Liquid-Refining Extraction And Consecutive Counter-Current Chromatography.

  2022cites this paper
• Anti-obesity effects of heat-transformed green tea extract through the activation of adipose tissue thermogenesis

  2022cites this paper
• Fluorometric and electrochemical dual-mode detection of toxic flavonoid rutin based on new nitrogen and sulfur co-doped carbon dots: Enhanced selectivity based on masking the interfering flavonoids with BSA complexation

  2022cites this paper
• Characterization, Large-Scale HSCCC Separation and Neuroprotective Effects of Polyphenols from Moringa oleifera Leaves

  2022cites this paper
• Preparation and use of tyrosine-capped copper nanoclusters as fluorescent probe to determine rutin

  2021cites this paper
• The Acute Toxicity of Rutin in Mice

  2021cites this paper
• Neuroprotective Effect of Quercetin during Cerebral Ischemic Injury Involves Regulation of Essential Elements, Transition Metals, Cu/Zn Ratio, and Antioxidant Activity

  2021cites this paper
• Dietary supplementation of rutin and rutin-rich buckwheat elevates endogenous glucagon-like peptide 1 levels to facilitate glycemic control in type 2 diabetic mice

  2021cites this paper
• Antioxidative effect of dietary flavonoid isoquercitrin on human ovarian granulosa cells HGL5 in vitro.

  2021cites this paper
• Structural elucidation of novel isoquercitrin-γ-cyclodextrin (IQC-γCD) molecular inclusion complexes of potential health benefits

  2021cites this paper
• Phytochemistry, Pharmacology and Toxicity of Medicinal Plants

  2021cites this paper
• 13-Weeks subchronic toxicity of isoquercitrin-γ-cyclodextrin (IQC-γCD) molecular inclusion complex in Sprague-Dawley rats.

  2021cites this paper
• Flavones and flavonols may have clinical potential as CK2 inhibitors in cancer therapy.

  2020cites this paper
• Determination of Pumpkin Leaves Equivalent; As a Measure of Pyhto Toxicity on Human Erythrocytes

  2020cites this paper
• Genista tridentata L.: A Rich Source of Flavonoids with Anti-Inflammatory Activity

  2020cites this paper
• An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin

  2020cites this paper
• Embryo-fetal developmental toxicity study of alpha-glycosyl isoquercitrin administered orally to New Zealand White rabbits

  2020cites this paper
• Identification of compound causing yellow bone discoloration following alpha-glycosyl isoquercitrin exposure in Sprague–Dawley rats

  2020cites this paper
• Anti-Obesity Effects of Soybean Embryo Extract and Enzymatically-Modified Isoquercitrin

  2020cites this paper
• Evaluation of acute oral toxicity induced by n-hexane extract of Leptadenia hastata Leaves in wistar rats

  2019cites this paper
• Flavonoids for preserving pancreatic beta cell survival and function: A mechanistic review.

  2019cites this paper
• The Beneficial Role of Rutin, A Naturally Occurring Flavonoid in Health Promotion and Disease Prevention: A Systematic Review and Update

  2019cites this paper
• In vitro response of human ovarian cancer cells to dietary bioflavonoid isoquercitrin

  2019cites this paper
• Scientific Committee Members

  2019cites this paper
• Antiosteoporotic activities of isoquercitrin in ovariectomized rats: Role of inhibiting hypoxia inducible factor-1 alpha.

  2019cites this paper
• Comprehensive evaluation of the flavonol anti-oxidants, alpha-glycosyl isoquercitrin and isoquercitrin, for genotoxic potential.

  2018cites this paper
• Rutin Ameliorates Acrylamide-Induced Hepatotoxicity and Biochemical Disturbance in Male Albino Rats

  2018cites this paper
• Red-emitting BSA-stabilized copper nanoclusters acted as a sensitive probe for fluorescence sensing and visual imaging detection of rutin.

  2018cites this paper
• Nonclinical safety of astilbin: A 4-week oral toxicity study in rats with genotoxicity, chromosomal aberration, and mammalian micronucleus tests.

  2017cites this paper
• 3-O-Glucosylation of quercetin enhances inhibitory effects on the adipocyte differentiation and lipogenesis.

  2017cites this paper
• The Stoichiometry of Isoquercitrin Complex with Iron or Copper Is Highly Dependent on Experimental Conditions

  2017cites this paper
• Sensitive electrochemical detection of rutin and isoquercitrin based on SH-β-cyclodextrin functionalized graphene-palladium nanoparticles.

  2017cites this paper
• Ninety-day toxicity and single-dose toxicokinetics study of alpha-glycosyl isoquercitrin in Sprague-Dawley rats.

  2016cites this paper
• Nitric oxide and Kir6.1 potassium channel mediate isoquercitrin-induced endothelium-dependent and independent vasodilation in the mesenteric arterial bed of rats.

  2016cites this paper
• Evaluation of in vivo Genotoxicity of Plant Flavonoids, Quercetin and Isoquercetin

  2016cites this paper
• TOXICOLOGICAL EVALUATION OF THE FLAVONOID RUTIN ON THE REPRODUCTIVE SYSTEM OF WISTAR RATS

  2016cites this paper
• Flavones and Flavonols may have Clinical Potential as CK2 Inhibitors in Cancer Therapy

  2015cites this paper
• Isoquercitrin: pharmacology, toxicology, and metabolism.

  2014influential citation
• Rutin and total isoflavone determination in soybean at different growth stages by using voltammetric methods

  2014cites this paper
• Informe del Comité Científico de la Agencia Española de Seguridad Alimentaria y Nutrición (AESAN) sobre condiciones de uso de determinadas sustancias distintas de vitaminas, minerales y plantas para ser empleadas en complementos alimenticios - 1

  2013cites this paper
• Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the use conditions for certain substances other than vitamins, minerals and plants in food supplements - 2

  2013cites this paper
• Evaluation of subchronic toxicity of the hydroethanolic extract of Tropaeolum majus in Wistar rats.

  2012cites this paper
• TOXICIDADE SUBCRÔNICA (28 DIAS) DE Tropaeolum majus L. EM RATOS

  2012cites this paper
• Cathodic adsorptive stripping voltammetric determination of rutin in soybean cultivars

  2012cites this paper
• Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

  2011cites this paper
• Fifty-two week chronic toxicity of enzymatically decomposed rutin in Wistar rats.

  2010cites this paper
• Evaluation of the immunotoxicological effects of Dimorphandra mollis Benth., Fabaceae, in rats

  2010cites this paper
• Toxic effects of Litsea elliptica Blume essential oil on red blood cells of Sprague-Dawley rats

  2009cites this paper
• Modulatory effects of rutin on biochemical and hematological parameters in hypercholesterolemic Golden Syrian hamsters.

  2009cites this paper
• Mutagenicity and safety evaluation of water extract of fermented Toona sinensis Roemor leaves.

  2009cites this paper
• Hypolipidemic and body fat-lowering effects of Fatclean in rats fed a high-fat diet.

  2009cites this paper
• Phenolic compounds rutin and o-coumaric acid ameliorate obesity induced by high-fat diet in rats.

  2009cites this paper
• Acute and chronic toxicological studies of the Brazilian phytopharmaceutical product Ierobina

  2008cites this paper
• Phenolic compounds: evidence for inhibitory effects against obesity and their underlying molecular signaling mechanisms.

  2008cites this paper
• Safety evaluation of water extracts of Toona sinensis Roemor leaf.

  2007cites this paper
• Acute and chronic toxicological studies of Dimorphandra mollis in experimental animals.

  2006cites this paper
• Development of a biosensor based on gilo peroxidase immobilized on chitosan chemically crosslinked with epichlorohydrin for determination of rutin.

  2006cites this paper
• A 13-week subchronic toxicity study of dietary administered morin in F344 rats.

  2006cites this paper
• Polyphenols of four medicinal plant extracts and relation with antifungal activities through in vitro and in silico studies

  year unknowncites this paper