Mode‐dependent inhibition by quinidine of Na+–Ca2+ exchanger current from guinea‐pig isolated ventricular myocytes

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Clinical and Experimental Pharmacology and Physiology

• Publication date

  2002-09-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1046/j.1440-1681.2002.03731.xPMID 12165041
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Reperfusion-induced Ins(1,4,5)P(3) generation and arrhythmogenesis require activation of the Na(+)/Ca(2+) exchanger.

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  1999cited by this paper
• Sodium/calcium exchange: its physiological implications.

  1999cited by this paper
• Quinidine.

  1998cited by this paper
• Inhibition of cardiac potassium currents by the vesnarinone analog OPC-18790: comparison with quinidine and dofetilide.

  1997cited by this paper
• A novel antagonist, No. 7943, of the Na+/Ca2+ exchange current in guinea‐pig cardiac ventricular cells

  1996cited by this paper
• The role of Na-Ca exchange current in the cardiac action potential.

  1996cited by this paper
• Molecular physiology of cardiac potassium channels.

  1996cited by this paper
• Ethanol inhibition of Ca2+ and Na+ currents in the guinea-pig heart.

  1995cited by this paper
• Afterdepolarizations and triggered activity.

  1992cited by this paper
• Suppression of time-dependent outward current in guinea pig ventricular myocytes. Actions of quinidine and amiodarone.

  1991cited by this paper
• Effects of N-acetylprocainamide and sotalol on ion currents in isolated guinea-pig ventricular myocytes.

  1990cited by this paper
• Interaction of some antiarrhythmic drugs with the heart sarcolemmal Na+-Ca2+ exchange system

  1989cited by this paper
• Inhibition of ICa in single frog cardiac cells by quinidine, flecainide, ethmozin, and ethacizin.

  1989influential reference
• Effects of Quinidine on Action Potentials and Ionic Currents in Isolated Canine Ventricular Myocytes

  1988cited by this paper
• Effect of tetrodotoxin, lidocaine, and quinidine on the transient inward current of sheep Purkinje fibres

  1988cited by this paper
• Block of cardiac sodium channels by antiarrhythmic drugs.

  1988cited by this paper
• Na+-Ca2+ exchange in sarcolemmal vesicles from bovine superior mesenteric artery.

  1988cited by this paper
• Antiarrhythmic agents: modulated receptor applications.

  1987cited by this paper
• Quinidine-induced inhibition of transient outward current in cardiac muscle.

  1987cited by this paper
• Block of activated and inactivated sodium channels by class-I antiarrhythmic drugs studied by using the maximum upstroke velocity (Vmax) of action potential in guinea-pig cardiac muscles.

  1987cited by this paper
• Effect of quinidine on Na-dependent 45Ca transport in isolated adult cardiac cells.

  1984cited by this paper
• Effects of procaine amide, quinidine and ethmozin on delayed afterdepolarizations.

  1983cited by this paper
• Inhibition of ouabain-induced increase in Na content of cultured myocardial cells by quinidine and procainamide.

  1983cited by this paper
• Steady-state serum quinidine concentration: role in prophylactic therapy following acute myocardial infarction.

  1979cited by this paper

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  2017cites this paper
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  2014cites this paper
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