Structurally Normal Corneas in Aldehyde Dehydrogenase 3a1-Deficient Mice

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Molecular and Cellular Biology

• Publication date

  2002-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.22.3.849-855.2002PMID 11784860PMCID PMC133561
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Corneal and stomach expression of aldehyde dehydrogenases: from fish to mammals.

  2001cited by this paper
• Enigma of the Abundant Water-Soluble Cytoplasmic Proteins of the Cornea: The “Refracton” Hypothesis

  2001cited by this paper
• AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach.

  2001cited by this paper
• Regulation of GSH in alphaA-expressing human lens epithelial cell lines and in alphaA knockout mouse lenses.

  2001cited by this paper
• Regulation of GSH in αA-expressing human lens epithelial cell lines and in αA knockout mouse lenses

  2001cited by this paper
• Aldehyde dehydrogenase gene superfamily: the 2000 update.

  2001cited by this paper
• Thiol Regulation in the Lens

  2000cited by this paper
• Omega -crystallin of the scallop lens. A dimeric aldehyde dehydrogenase class 1/2 enzyme-crystallin.

  2000cited by this paper
• Review: A Case for Corneal Crystallins

  2000cited by this paper
• Evidence for Gelsolin as a Corneal Crystallin in Zebrafish*

  2000cited by this paper
• The function of alpha-crystallin in vision.

  2000cited by this paper
• Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping.

  1999cited by this paper
• The cellular basis of corneal transparency: evidence for 'corneal crystallins'.

  1999cited by this paper
• Identification of a Cytosolic NADP+-dependent Isocitrate Dehydrogenase That Is Preferentially Expressed in Bovine Corneal Epithelium

  1999cited by this paper
• Four amino acid changes are associated with the Aldh3a1 locus polymorphism in mice which may be responsible for corneal sensitivity to ultraviolet light.

  1999cited by this paper
• Gene sharing in lens and cornea: facts and implications.

  1998influential reference
• Development of an ultrasensitive in vitro assay to monitor growth of primary cell cultures with reduced mitotic activity.

  1998cited by this paper
• Multifunctional Lens Crystallins and Corneal Enzymes: More than Meets the Eye

  1998cited by this paper
• alpha-Crystallin quaternary structure and interactive properties control eye lens transparency.

  1998cited by this paper
• Aldehyde dehydrogenase class 3 expression: identification of a cornea-preferred gene promoter in transgenic mice.

  1997cited by this paper
• Transketolase Is a Major Protein in the Mouse Cornea*

  1996cited by this paper
• Effect of UVB radiation on corneal aldehyde dehydrogenase.

  1996cited by this paper
• Letter to the Editors: Corneal Aldehyde Dehydrogenase Displays Antioxidant Properties

  1996cited by this paper
• A Retinaldehyde Dehydrogenase as a Structural Protein in a Mammalian Eye Lens

  1996cited by this paper
• Corneal aldehyde dehydrogenase displays antioxidant properties.

  1996cited by this paper
• Quantitation of Ultraviolet Light-Absorbing Fractions of the Cornea

  1995cited by this paper
• Evidence that α-crystallin prevents non-specific protein aggregation in the intact eye lens

  1995cited by this paper
• Evidence that alpha-crystallin prevents non-specific protein aggregation in the intact eye lens.

  1995cited by this paper
• Differential Corneal Sensitivity to Ultraviolet Light Among Inbred Strains of Mice: Correlation of Ultraviolet B Sensitivity with Aldehyde Dehydrogenase Deficiency

  1994cited by this paper
• Members of the ALDH gene family are lens and corneal crystallins.

  1993cited by this paper
• Efficacy of tribromoethanol anesthesia in mice.

  1993cited by this paper
• Aldehyde dehydrogenase-derived omega-crystallins of squid and octopus. Specialization for lens expression.

  1993cited by this paper
• Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.

  1992cited by this paper
• Kinetic properties of the bovine corneal aldehyde dehydrogenase (BCP 54).

  1992cited by this paper
• Aldehyde dehydrogenases and their role in carcinogenesis.

  1992influential reference
• The muscle-derived lens of a squid bioluminescent organ is biochemically convergent with the ocular lens. Evidence for recruitment of aldehyde dehydrogenase as a predominant structural protein.

  1992cited by this paper
• Taxon-specific recruitment of enzymes as major soluble proteins in the corneal epithelium of three mammals, chicken, and squid.

  1992cited by this paper
• Effects of prokaryotic termination signals on RNA polymerase II transcription in HeLa cells.

  1991cited by this paper
• Detection of aldehyde dehydrogenase activity in human corneal extracts.

  1991cited by this paper
• Purification and properties of baboon corneal aldehyde dehydrogenase: proposed UVR protective role.

  1991cited by this paper
• Lipid aldehyde oxidation as a physiological role for class 3 aldehyde dehydrogenases.

  1991cited by this paper
• Crystallins of the octopus lens. Recruitment from detoxification enzymes.

  1991cited by this paper
• Bovine corneal aldehyde dehydrogenase: the major soluble corneal protein with a possible dual protective role for the eye.

  1990cited by this paper
• Characterization of rat cornea aldehyde dehydrogenase.

  1989cited by this paper
• Ocular NAD-dependent alcohol dehydrogenase and aldehyde dehydrogenase in the baboon.

  1986cited by this paper
• Isolation of corneal epithelium with Dispase II or EDTA. Effects on the basement membrane zone.

  1985cited by this paper
• Rat liver aldehyde dehydrogenase. I. Isolation and characterization of four high Km normal liver isozymes.

  1984cited by this paper
• Effect of change in concentration upon lens turbidity as predicted by the random fluctuation theory.

  1983cited by this paper
• Short-range order of crystallin proteins accounts for eye lens transparency

  1983cited by this paper
• Tissue and species specificity of BCP 54, the major soluble protein of bovine cornea.

  1981cited by this paper
• Isolation and characterization of BCP 54, the major soluble protein of bovine cornea.

  1981cited by this paper
• Oxygen toxicity: membrane damage by free radicals.

  1976cited by this paper
• A general method for isolation of high molecular weight DNA from eukaryotes.

  1976cited by this paper

• Understanding coenzyme Q

  2024cites this paper
• Identification of a peptide ligand for human ALDH3A1 through peptide phage display: Prediction and characterization of protein interaction sites and inhibition of ALDH3A1 enzymatic activity

  2023cites this paper
• Aldehyde Dehydrogenase and Aldo-Keto Reductase Enzymes: Basic Concepts and Emerging Roles in Diabetic Retinopathy

  2023cites this paper
• Analysis and comparison of tear protein profiles in dogs using different tear collection methods

  2022cites this paper
• Multiple roles of Pax6 in corneal limbal epithelial cells and maturing epithelial cell adhesion

  2022cites this paper
• Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype

  2022cites this paper
• Multiple roles of Pax6 in postnatal cornea development.

  2022cites this paper
• Composition, structure and function of the corneal stroma.

  2020cites this paper
• Moonlighting in drug metabolism

  2020cites this paper
• Abundant Perithecial Protein (APP) from Neurospora is a primitive functional analog of ocular crystallins.

  2019cites this paper
• Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and Cancer.

  2018cites this paper
• Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes

  2018cites this paper
• Instructions for use Title Mouse aldehyde dehydrogenase ALDH 3 B 2 is localized to lipid droplets via two C-terminal tryptophanresidues and lipid modification Author ( s )

  2017cites this paper
• Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry.

  2017cites this paper
• Human aldehyde dehydrogenase 3A1 (ALDH3A1) exhibits chaperone-like function.

  2017cites this paper
• ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis

  2016cites this paper
• Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification.

  2015cites this paper
• Cellular and extracellular matrix modulation of corneal stromal opacity.

  2014cites this paper
• Therapeutic potential of targeting lipid aldehydes and lipoxidation end-products in the treatment of ocular disease.

  2013cites this paper
• Identification, kinetic and structural characterization of small molecule inhibitors of aldehyde dehydrogenase 3a1 (ALDH3A1) as an adjuvant therapy for reversing cancer chemoresistance

  2013cites this paper
• Investigating the role of aldehyde dehydrogenase 3A1 in regulation of corneal epithelial homeostasis

  2013cites this paper
• αA-crystallin in the pathogenesis and intervention of experimental murine corneal neovascularization.

  2012cites this paper
• Differential response of lens crystallins and corneal crystallins in degenerative corneas.

  2012cites this paper
• Aldehyde dehydrogenases are regulators of hematopoietic stem cell numbers and B-cell development.

  2012cites this paper
• Corneal aldehyde dehydrogenases: multiple functions and novel nuclear localization.

  2010cites this paper
• Physiological expression of lens α-, β-, and γ-crystallins in murine and human corneas

  2010cites this paper
• Differential expression patterns and developmental roles of duplicated scinderin‐like genes in zebrafish

  2009cites this paper
• Non-P 450 aldehyde oxidizing enzymes : the aldehyde dehydrogenase superfamily

  2009cites this paper
• 4-HNE inhibits tube formation and up-regulates chondromodulin-I in human endothelial cells.

  2009cites this paper
• Corneal crystallins and the development of cellular transparency.

  2008cites this paper
• Identification of Candidate Klf 4 Target Genes Reveals the Molecular Basis of the Diverse Regulatory Roles of Klf 4 in the Mouse Cornea

  2008cites this paper
• The transparent lens and cornea in the mouse and zebra fish eye.

  2008cites this paper
• Identification of candidate Klf4 target genes reveals the molecular basis of the diverse regulatory roles of Klf4 in the mouse cornea.

  2008cites this paper
• Gene expression of the mouse corneal crystallin Aldh3a1: activation by Pax6, Oct1, and p300.

  2008cites this paper
• Eye evolution: lens and cornea as an upgrade of animal visual system.

  2008cites this paper
• Evolution of Mollusc Lens Crystallins: Glutathione S-transferase/S-crystallins and Aldehyde Dehydrogenase/Ω-crystallins*

  2008cites this paper
• Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

  2008cites this paper
• Mouse Models of the Cornea and Lens: Understanding Ocular Disease

  2008cites this paper
• Multiple and Additive Functions of ALDH3A1 and ALDH1A1

  2007cites this paper
• ALDH3A1: a corneal crystallin with diverse functions.

  2007cites this paper
• Duplicated gelsolin family genes in zebrafish: a novel scinderin‐like gene (scinla) encodes the major corneal crystallin

  2007cites this paper
• The human cornea proteome: bioinformatic analyses indicate import of plasma proteins into the cornea.

  2006cites this paper
• Serial analysis of gene expression (SAGE) in the rat limbal and central corneal epithelium.

  2006cites this paper
• Aldehyde dehydrogenase (ALDH) 3A1 expression by the human keratocyte and its repair phenotypes.

  2006cites this paper
• Human Aldehyde Dehydrogenase 3A1 Inhibits Proliferation and Promotes Survival of Human Corneal Epithelial Cells*

  2005cites this paper
• Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stress.

  2005cites this paper
• Keratocyte reflectivity and corneal haze.

  2004cites this paper
• Preferential Transcription of Rabbit Aldh1a1 in the Cornea: Implication of Hypoxia-Related Pathways

  2004cites this paper
• Abundant corneal gelsolin in Zebrafish and the 'four-eyed' fish, Anableps anableps: possible analogy with multifunctional lens crystallins.

  2004cites this paper
• Ocular surface epithelial and stem cell development.

  2004cites this paper
• Downstream effects of ROCK signaling in cultured human corneal stromal cells: microarray analysis of gene expression.

  2004cites this paper
• Proteomic Analysis of the Soluble Fraction from Human Corneal Fibroblasts with Reference to Ocular Transparency*

  2004cites this paper
• Alkali burn causes aldehyde dehydrogenase 3A1 (ALDH3A1) decrease in mouse cornea.

  2004cites this paper
• Postnatal gene expression in the normal mouse cornea by SAGE.

  2004cites this paper
• Serum albumin in mammalian cornea: implications for clinical application.

  2003cites this paper
• Ultraviolet radiation decreases expression and induces aggregation of corneal ALDH3A1.

  2003cites this paper
• Molecular Cloning and Baculovirus Expression of the Rabbit Corneal Aldehyde Dehydrogenase (ALDH1A1) cDNA

  2003cites this paper
• Human aldehyde dehydrogenase 3A1 (ALDH3A1): biochemical characterization and immunohistochemical localization in the cornea.

  2003cites this paper
• Transketolase Haploinsufficiency Reduces Adipose Tissue and Female Fertility in Mice

  2002cites this paper