Population Differentiation as an Indicator of Recent Positive Selection in Humans: An Empirical Evaluation

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Genetics

• Publication date

  2009-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1534/genetics.109.107722PMID 19737746PMCID PMC2778960
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Signals of recent positive selection in a worldwide sample of human populations.

  2009cited by this paper
• Large Allele Frequency Differences between Human Continental Groups are more Likely to have Occurred by Drift During range Expansions than by Selection

  2009cited by this paper
• Population genomic analysis of ALMS1 in humans reveals a surprisingly complex evolutionary history.

  2009cited by this paper
• A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals.

  2009cited by this paper
• The Timing of Selection at the Human FOXP2 Gene

  2008cited by this paper
• Enhanced ectodysplasin‐A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form

  2008cited by this paper
• Natural selection has driven population differentiation in modern humans

  2008cited by this paper
• Ethnic Related Selection for an ADH Class I Variant within East Asia

  2008cited by this paper
• A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness.

  2008cited by this paper
• EDA2R is associated with androgenetic alopecia.

  2008cited by this paper
• Detecting Local Adaptation Using the Joint Sampling of Polymorphism Data in the Parental and Derived Populations

  2008cited by this paper
• A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia

  2008cited by this paper
• Competing Interests: The authors...

  2008cited by this paper
• Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

  2007cited by this paper
• Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth

  2007cited by this paper
• The derived FOXP2 variant of modern humans was shared with Neandertals.

  2007cited by this paper
• A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome

  2007cited by this paper
• Extreme individual marker FST values do not imply population-specific selection in humans: the NRG1 example

  2007cited by this paper
• Genome-wide detection and characterization of positive selection in human populations

  2007cited by this paper
• Identification and Analysis of Genomic Regions with Large Between‐Population Differentiation in Humans

  2007cited by this paper
• Positive Natural Selection in the Human Lineage

  2006influential reference
• A Map of Recent Positive Selection in the Human Genome

  2006influential reference
• A SNP in the ABCC11 gene is the determinant of human earwax type

  2006cited by this paper
• How reliable are empirical genomic scans for selective sweeps?

  2006cited by this paper
• CEACAMs: their role in physiology and pathophysiology

  2006cited by this paper
• Going East: New Genetic and Archaeological Perspectives on the Modern Human Colonization of Eurasia

  2006cited by this paper
• Scanning the human genome for signals of selection.

  2006cited by this paper
• Calibrating a coalescent simulation of human genome sequence variation.

  2005influential reference
• SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans

  2005cited by this paper
• Haploview: analysis and visualization of LD and haplotype maps

  2005cited by this paper
• Genomic regions exhibiting positive selection identified from dense genotype data.

  2005cited by this paper
• HIERFSTAT , a package for R to compute and test hierarchical F -statistics

  2005cited by this paper
• The HKA Test Revisited

  2004cited by this paper
• A haplotype map of the human genome

  2003cited by this paper
• Human Evolutionary Genetics

  2003cited by this paper
• A comparison of bayesian methods for haplotype reconstruction from population genotype data.

  2003influential reference
• A haplotype map of the human genome.

  2003cited by this paper
• Genetic Structure of Human Populations

  2002cited by this paper
• Molecular evolution of FOXP2, a gene involved in speech and language

  2002influential reference
• Complex signatures of natural selection at the Duffy blood group locus.

  2002influential reference
• Detecting recent positive selection in the human genome from haplotype structure

  2002cited by this paper
• Emergence of Modern Human Behavior: Middle Stone Age Engravings from South Africa

  2002cited by this paper
• A Human Genome Diversity Cell Line Panel

  2002cited by this paper
• Generating samples under a Wright-Fisher neutral model of genetic variation

  2002cited by this paper
• A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

  2001cited by this paper
• Hitchhiking under positive Darwinian selection.

  2000cited by this paper
• Median-joining networks for inferring intraspecific phylogenies.

  1999influential reference
• Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection.

  1997influential reference
• Statistical tests of neutrality of mutations.

  1993cited by this paper
• Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.

  1989cited by this paper
• Supporting Online Material Materials and Methods Figs. S1 to S3 Tables S1 to S5 References Worldwide Human Relationships Inferred from Genome-wide Patterns of Variation

  year unknowninfluential reference

• Reflections on the Human Genome Diversity Project: a conversation with Marcus W. Feldman, Henry T. Greely, and Mary-Claire King.

  2026cites this paper
• Adaptive Evolution of Two Distinct Adaptive Haplotypes of Neanderthal Origin at the Immunoglobulin Heavy-chain Locus in East Asian and European Populations

  2024cites this paper
• Understanding signatures of positive natural selection in human zinc transporter genes

  2022cites this paper
• Author Correction: Understanding signatures of positive natural selection in human zinc transporter genes

  2022influential citation
• The genomic origins of the world’s first farmers

  2022cites this paper
• Positive Selection in Human Populations: Practical Aspects and Current Knowledge

  2021cites this paper
• Genetic lineage of the Amami islanders inferred from classical genetic markers

  2021cites this paper
• Difference in the Proportions of Deleterious Variations Within and Between Populations Influences the Estimation of FST

  2021cites this paper
• Surveillance of Aedes aegypti populations in the city of Praia, Cape Verde: Zika virus infection, insecticide resistance and genetic diversity

  2020cites this paper
• Temporal distribution of deleterious variations influences the estimation of FST

  2019cites this paper
• Characterisation of a second gain of function EDAR variant, encoding EDAR380R, in East Asia

  2019cites this paper
• How well do we understand the basis of classic selective sweeps in humans?

  2019cites this paper
• HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases

  2019cites this paper
• These aren’t the loci you’e looking for: Principles of effective SNP filtering for molecular ecologists

  2018cites this paper
• Comparative Genomics in Homo sapiens.

  2018cites this paper
• Sequence diversity of the Rh blood group system in Basques

  2018cites this paper
• Analysis of population-specific pharmacogenomic variants using next-generation sequencing data

  2017cites this paper
• Fast and robust detection of ancestral selective sweeps

  2017cites this paper
• Ancient pathogen-driven adaptation triggers increased susceptibility to non-celiac wheat sensitivity in present-day European populations

  2016cites this paper
• Evidence of Recent Intricate Adaptation in Human Populations

  2016cites this paper
• Detailed analysis of inversions predicted between two human genomes: errors, real polymorphisms, and their origin and population distribution

  2016cites this paper
• Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A

  2016cites this paper
• Lectin Complement Protein Collectin 11 (CL-K1) and Susceptibility to Urinary Schistosomiasis

  2015cites this paper
• Análisis, validación y estudio poblacional de las inversiones entre dos genomas humanos

  2014cites this paper
• Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences

  2014cites this paper
• Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer

  2014cites this paper
• Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa

  2014cites this paper
• Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences

  2014cites this paper
• Différenciation génétique des populations humaines pour les gènes de la réponse aux médicaments

  2014cites this paper
• A general linear model-based approach for inferring selection to climate

  2013cites this paper
• Integrative annotation of variants from 1 , 092 humans : application to cancer genomics ”

  2013cites this paper
• Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics

  2013cites this paper
• Modeling recent human evolution in mice by expression of a selected EDAR variant.

  2013cites this paper
• The adaptive variant EDARV370A is associated with straight hair in East Asians

  2013cites this paper
• Evolutionary genetics of the human Rh blood group system

  2012cites this paper
• ‘Sifting the significance from the data’ - the impact of high-throughput genomic technologies on human genetics and health care

  2012cites this paper
• Positive Selection in the Chromosome 16 VKORC1 Genomic Region Has Contributed to the Variability of Anticoagulant Response in Humans

  2012cites this paper
• Evolutionary forces shaping genomic islands of population differentiation in humans

  2012cites this paper
• On the genetic interpretation of Between-Group PCA on SNP data

  2012cites this paper
• Consequences of a poecilogonous life history for genetic structure in coastal populations of the polychaete Streblospio benedicti

  2012cites this paper
• An evolutionary history of the selectin gene cluster in humans

  2012cites this paper
• Rapid Recent Human Evolution and the Accumulation of Balanced Genetic Polymorphisms

  2011cites this paper
• Exploration of signals of positive selection derived from genotype-based human genome scans using re-sequencing data

  2011cites this paper
• Replication of the Association of a MET Variant with Autism in a Chinese Han Population

  2011cites this paper
• Comparison of FST outlier tests for SNP loci under selection

  2011cites this paper
• Population genetic structure in Indian Austroasiatic speakers: the role of landscape barriers and sex-specific admixture.

  2011cites this paper
• The origin of Eastern European Jews revealed by autosomal, sex chromosomal and mtDNA polymorphisms

  2010cites this paper
• Schizophrenia and vitamin D related genes could have been subject to latitude-driven adaptation

  2010cites this paper
• Population genetics of venous thromboembolism

  2010cites this paper
• Fine-scale population structure and the era of next-generation sequencing.

  2010cites this paper
• These aren’t the loci you’re looking for: Principles of effective SNP These aren’t the loci you’re looking for: Principles of effective SNP filtering for molecular ecologists filtering for molecular ecologists

  year unknowncites this paper