Clinical testing and spinal cord removal in a mouse model for amyotrophic lateral sclerosis (ALS).

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Visualized Experiments

• Publication date

  2012-03-17

• Fields of study

  Medicine

• Identifiers
  DOI 10.3791/3936PMID 22453893PMCID PMC3415170
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Guidelines for preclinical animal research in ALS/MND: A consensus meeting

  2010cited by this paper
• Neuromuscular disease models and analysis.

  2010cited by this paper
• Significance of behavioural tests in a transgenic mouse model of amyotrophic lateral sclerosis (ALS).

  2010cited by this paper
• Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells.

  2009cited by this paper
• Pre-symptomatic detection of chronic motor deficits and genotype prediction in congenic B6.SOD1(G93A) ALS mouse model.

  2009cited by this paper
• Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis

  2008cited by this paper
• Behavioral phenotyping strategies for mutant mice.

  2008cited by this paper
• Ablation of Proliferating Microglia Does Not Affect Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis Caused by Mutant Superoxide Dismutase

  2008cited by this paper
• Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.

  2008cited by this paper
• Design, power, and interpretation of studies in the standard murine model of ALS

  2008cited by this paper
• Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia

  2006cited by this paper
• Optimal methods to characterize the G93A mouse model of ALS

  2005cited by this paper
• Assessing disease onset and progression in the SOD1 mouse model of ALS

  2003cited by this paper
• Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration.

  1999cited by this paper
• Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.

  1994cited by this paper

• Persistent NRG1 Type III Overexpression in Spinal Motor Neurons Has No Therapeutic Effect on ALS-Related Pathology in SOD1G93A Mice

  2023cites this paper
• Transplanted Human Bone Marrow Endothelial Progenitor Cells Prolong Functional Benefits and Extend Survival of ALS Mice Likely via Blood-Spinal Cord Barrier Repair

  2023cites this paper
• Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1G93A mouse model of amyotrophic lateral sclerosis

  2022cites this paper
• BL-918, a small-molecule activator of ULK1, induces cytoprotective autophagy for amyotrophic lateral sclerosis therapy

  2022cites this paper
• DOK7 Gene Therapy Enhances Neuromuscular Junction Innervation and Motor Function in Aged Mice

  2020cites this paper
• Brain Protease Activated Receptor 1 Pathway: A Therapeutic Target in the Superoxide Dismutase 1 (SOD1) Mouse Model of Amyotrophic Lateral Sclerosis

  2020cites this paper
• Curcumin Effects on Memory Impairment and Restoration of Irregular Neuronal Distribution in the Hippocampal CA1 Region After Global Cerebral Ischemia in Male Rats

  2019cites this paper
• Mass cytometry analysis of immune cells in the brain

  2018cites this paper
• HTLV‐1 infection‐induced motor dysfunction, memory impairment, depression, and brain tissues oxidative damage in female BALB/c mice

  2018cites this paper
• Differenzierung der Pharmakotherapie mit Fasudil und Riluzol im SOD1-G93A Mausmodell der Amyotrophen Lateralsklerose

  2018influential citation
• Rho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis—Symptomatic Treatment Potential after Disease Onset

  2017cites this paper
• Bioluminescence Imaging of Neuroinflammation in Transgenic Mice After Peripheral Inoculation of Alpha-Synuclein Fibrils.

  2017cites this paper
• Mouse models of neurodegenerative disease: preclinical imaging and neurovascular component

  2017cites this paper
• Organotypic Spinal Cord Slice Cultures and a Method to Detect Cell Proliferation in These Slices

  2016cites this paper
• FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation

  2016cites this paper
• Targeted lentiviral-mediated delivery of progranulin cDNA in a genetic model of amyotrophic lateral sclerosis

  2015cites this paper
• The rho kinase inhibitor Y-27632 improves motor performance in male SOD1G93A mice

  2014cites this paper
• Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis

  2013cites this paper