The architecture of RNA polymerase fidelity

The basis for transcriptional fidelity by RNA polymerase is not understood, but the 'trigger loop', a conserved structural element that is rearranged in the presence of correct substrate nucleotides, is thought to be critical. A study just published in BMC Biology sheds new light on the ways in which the trigger loop may promote selection of correct nucleotide triphosphate substrates.See research article http://www.biomedcentral.com/1741-7007/8/54

• Publication year

  2010

• Venue

  BMC Biology

• Publication date

  2010-06-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1186/1741-7007-8-85PMID 20598112PMCID 2889878
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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