STUDY ON THE POSSIBLE SIMILAR MECHANISM OF ULTRA LOW DOSE-INDUCED HYPERALGESIA AND DEVELOPMENT OF TOLERANCE TO ANALGESIA IN MALE RATS: AN STUDY BASED ON THE ROLE OF GS SIGNALING PATHWAY

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Physiology and Pharmacology

• Publication date

  2006-03-10

• Fields of study

  Medicine

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Changes in G proteins genes expression in rat lumbar spinal cord support the inhibitory effect of chronic pain on the development of tolerance to morphine analgesia.

  2005cited by this paper
• Reduced development of tolerance to the analgesic effects of morphine and clonidine in PKC&ggr; mutant mice

  2001cited by this paper
• Antagonists of excitatory opioid receptor functions enhance morphine's analgesic potency and attenuate opioid tolerance/dependence liability

  2000cited by this paper
• Enhanced morphine analgesia in mice lacking beta-arrestin 2.

  1999cited by this paper
• Evidence for opiate-activated NMDA processes masking opiate analgesia in rats.

  1999cited by this paper
• Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions.

  1999cited by this paper
• Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GM1 ganglioside-regulated opioid receptor functions.

  1998cited by this paper
• Chronic morphine augments G(beta)(gamma)/Gs(alpha) stimulation of adenylyl cyclase: relevance to opioid tolerance.

  1998cited by this paper
• The Role of GM1 Ganglioside in Regulating Excitatory Opioid Effects a

  1998cited by this paper
• Morphine-activated opioid receptors elude desensitization by β-arrestin

  1998cited by this paper
• Chronic Morphine Augments G bg /G s a Stimulation of Adenylyl Cyclase: Relevance to Opioid Tolerance

  1998cited by this paper
• GM1 Ganglioside‐induced Modulation of Opioid Receptor‐mediated Functions

  1998cited by this paper
• Ultra-low doses of naltrexone or etorphine increase morphine's antinociceptive potency and attenuate tolerance/dependence in mice.

  1997cited by this paper
• The Competitive α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionate Receptor Antagonist LY293558 Attenuates and Reverses Analgesic Tolerance to Morphine But Not to Delta or Kappa Opioids

  1997cited by this paper
• Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits.

  1996cited by this paper
• Adenylylcyclase Supersensitization in μ-Opioid Receptor-transfected Chinese Hamster Ovary Cells Following Chronic Opioid Treatment (*)

  1995cited by this paper
• Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment.

  1995cited by this paper
• Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia

  1993cited by this paper
• Nitric oxide (NO) and nociceptive processing in the spinal cord.

  1993cited by this paper
• Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells.

  1993cited by this paper
• After chronic opioid exposure sensory neurons become supersensitive to the excitatory effects of opioid agonists and antagonists as occurs after acute elevation of GM1 ganglioside.

  1992cited by this paper
• A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function.

  1991cited by this paper
• Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture.

  1989cited by this paper
• Modulation of adenylate cyclase activity of mouse spinal cord-ganglion explants by opioids, serotonin and pertussis toxin.

  1988cited by this paper
• Direct Demonstration of the Activation of UDP‐N‐Acetylgalactosamine: [GM3]N‐Acetylgalactosaminyltransferase by Cyclic AMP

  1986cited by this paper
• Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance.

  1975cited by this paper

• Chronic forced swim stress inhibits ultra-low dose morphine-induced hyperalgesia in rats

  2007cites this paper