alpha-Lipoic acid reduces matrix metalloproteinase activity in MDA-MB-231 human breast cancer cells.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Nutrition Research

• Publication date

  2010-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.nutres.2010.06.009PMID 20650348
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intestinal tumour chemoprevention with the antioxidant lipoic acid stimulates the growth of breast cancer.

  2008cited by this paper
• Alpha‐lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway

  2008cited by this paper
• Influence of conjugated linoleic acid isomers on the metastasis of colon cancer cells in vitro and in vivo.

  2007cited by this paper
• Proteasome Inhibition Induces Glutathione Synthesis and Protects Cells from Oxidative Stress

  2007cited by this paper
• Dietary lignan intake and postmenopausal breast cancer risk by estrogen and progesterone receptor status.

  2007cited by this paper
• α-Lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-κB transcriptional activity

  2007cited by this paper
• Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity.

  2007cited by this paper
• Chemoprevention of precancerous gastric lesions with antioxidant vitamin supplementation: a randomized trial in a high-risk population.

  2007cited by this paper
• Protection against arsenic trioxide-induced autophagic cell death in U118 human glioma cells by use of lipoic acid.

  2006cited by this paper
• The Long-term Survival of a Patient With Pancreatic Cancer With Metastases to the Liver After Treatment With the Intravenous α-Lipoic Acid/Low-Dose Naltrexone Protocol

  2006influential reference
• Molecular Structure of a 9-MDa Icosahedral Pyruvate Dehydrogenase Subcomplex Containing the E2 and E3 Enzymes Using Cryoelectron Microscopy*

  2006cited by this paper
• Dietary Risk Factors for Colon and Rectal Cancers: A Comparative Case-Control Study

  2006cited by this paper
• Biological assays and genomic analysis reveal lipoic acid modulation of endothelial cell behavior and gene expression.

  2006cited by this paper
• α-lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2−.-generation

  2005cited by this paper
• α lipoic acid inhibits human T‐cell migration: Implications for multiple sclerosis

  2004cited by this paper
• Fruit and vegetable intake and risk of major chronic disease.

  2004cited by this paper
• Inhibitory effect of emodin on tumor invasion through suppression of activator protein-1 and nuclear factor-kappaB.

  2004cited by this paper
• Lignans and Tamoxifen, Alone or in Combination, Reduce Human Breast Cancer Cell Adhesion, Invasion and Migration in vitro

  2003cited by this paper
• Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.

  2003cited by this paper
• Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line.

  2003cited by this paper
• Implications of the Activation of Matrix Metalloproteinase-2 (MMP-2) on the Metastasis in Breast Cancer

  2002cited by this paper
• Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid.

  2002cited by this paper
• Differential effects of the antioxidant alpha-lipoic acid on the proliferation of mitogen-stimulated peripheral blood lymphocytes and leukaemic T cells.

  2002cited by this paper
• Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis.

  2002cited by this paper
• Expression of transmembrane 4 superfamily (TM4SF) proteins and their role in hepatic stellate cell motility and wound healing migration.

  2002cited by this paper
• Suppression of breast cancer invasion and migration by indole-3-carbinol: associated with up-regulation of BRCA1 and E-cadherin/catenin complexes

  2000cited by this paper
• Tissue inhibitors of metalloproteinases: evolution, structure and function.

  2000cited by this paper
• Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line.

  2000cited by this paper
• Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis.

  2000cited by this paper
• Ethanol enhances erbB-mediated migration of human breast cancer cells in culture

  2000cited by this paper
• Matrix metalloproteinases and metastasis

  1999cited by this paper
• Regulation of matrix metalloproteinase expression in tumor invasion

  1999cited by this paper
• Effects of alpha-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids.

  1998cited by this paper
• Effects of α-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids

  1998cited by this paper
• Matrix metalloproteinase‐2 immunoreactive protein

  1998cited by this paper
• Changing views of the role of matrix metalloproteinases in metastasis.

  1997cited by this paper
• Molecular regulation of cellular invasion--role of gelatinase A and TIMP-2.

  1996cited by this paper
• alpha-Lipoic acid as a biological antioxidant.

  1995cited by this paper
• Tumor cell interactions with the extracellular matrix during invasion and metastasis.

  1993cited by this paper
• Matrix metalloproteinases and their inhibitors in connective tissue remodeling

  1991cited by this paper
• Metastatic potential correlates with enzymatic degradation of basement membrane collagen

  1980cited by this paper

• Redox Balance in Cancer in the Context of Tumor Prevention and Treatment

  2025cites this paper
• Lipoic Acid/Choline Ionic Liquid Enhanced Intratumoral Heat/Mass Transfer for Suppressing Thermo‐Mediated Tumor Relapse and Metastasis

  2025cites this paper
• A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease

  2025cites this paper
• Ethanolic extract of Euphorbia royleana Boiss. reduces metastasis of breast cancer cells and inhibits tumor progression in vivo

  2024cites this paper
• Lipoic acid alters the microRNA signature in breast cancer cells.

  2024cites this paper
• Alpha-lipoic Acid: An Antioxidant with Anti-Aging Properties for Disease Therapy.

  2024cites this paper
• Anticancer effects of alpha-lipoic acid, a potent organosulfur compound by modulating matrix metalloproteinases and apoptotic markers in osteosarcoma MG-63 cells.

  2024cites this paper
• The Multifaceted Role of Alpha-Lipoic Acid in Cancer Prevention, Occurrence, and Treatment

  2024cites this paper
• Alpha-Lipoic Acid, Auraptene, and Particularly Their Combination Prevent the Metastasis of U87 Human Glioblastoma Cells

  2023cites this paper
• Alpha-Lipoic Acid Reduces Cell Growth, Inhibits Autophagy, and Counteracts Prostate Cancer Cell Migration and Invasion: Evidence from In Vitro Studies

  2023cites this paper
• Alpha-lipoic acid induced apoptosis of PC3 prostate cancer cells through an alteration on mitochondrial membrane depolarization and MMP-9 mRNA expression

  2023cites this paper
• Metalloproteases in Pain Generation and Persistence: A Possible Target?

  2023cites this paper
• Investigation of the Potential Effects of Alpha-Lipoic Acid on Human Degenerated Intervertebral Disc Tissue Primary Cell Cultures.

  2021cites this paper
• Evaluation of Dissolution Profiles of a Newly Developed Solid Oral Immediate-Release Formula Containing Alpha-Lipoic Acid

  2021cites this paper
• An Overview of the Antioxidant Effects of Ascorbic Acid and Alpha Lipoic Acid (in Liposomal Forms) as Adjuvant in Cancer Treatment

  2020cites this paper
• α-Lipoic acid prevents the ionizing radiation-induced epithelial-mesenchymal transition and enhances the radiosensitivity in breast cancer cells.

  2020cites this paper
• Treating the pH gradient inversion

  2020cites this paper
• Role of coenzymes in cancer metabolism.

  2020cites this paper
• Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation

  2020cites this paper
• Lipoic acid-induced oxidative stress abrogates IGF-1R maturation by inhibiting the CREB/furin axis in breast cancer cell lines

  2020cites this paper
• Alpha‐lipoic acid: A possible pharmacological agent for treating dry eye disease and retinopathy in diabetes

  2020cites this paper
• Lipoic acid a multi-level molecular inhibitor of tumorigenesis.

  2019cites this paper
• Apoptotic Induction and Anti-Migratory Effects of Rhazya Stricta Fruit Extracts on a Human Breast Cancer Cell Line

  2019cites this paper
• Intérêt de l’utilisation de stratégies anti-métaboliques pour le traitement du cancer du sein

  2019influential citation
• The Effect of Glutamine Supplementation on Oxidative Stress and Matrix Metalloproteinase 2 and 9 After Exhaustive Exercise

  2019cites this paper
• &agr;‐Lipoic acid inhibits the migration and invasion of breast cancer cells through inhibition of TGF&bgr; signaling

  2018cites this paper
• Thiol-Containing Antioxidants Reduce Accumulation of Collagen I on the Surface of Human Skin Fibroblasts

  2018cites this paper
• Hard clam extracts induce atypical apoptosis in human gastric cancer cells

  2017cites this paper
• Lipoic acid functionalized SiO2@Ag nanoparticles. Synthesis, characterization and evaluation of biological activity.

  2017cites this paper
• The disulfide compound α-lipoic acid and its derivatives: A novel class of anticancer agents targeting mitochondria.

  2016cites this paper
• Multiple protective mechanisms of alpha-lipoic acid in oxidation, apoptosis and inflammation against hydrogen peroxide induced toxicity in human lymphocytes

  2015cites this paper
• The effects of alpha-lipoic acid on breast of female albino rats exposed to malathion: Histopathological and immunohistochemical study.

  2015cites this paper
• [Antioxidant use as dietary therapy in patients with multiple sclerosis].

  2015cites this paper
• AMPK/p53 Axis Is Essential for α-Lipoic Acid–Regulated Metastasis in Human and Mouse Colon Cancer Cells

  2015cites this paper
• Matrix metalloproteinase activity in transformed cells exposed to an antioxidant

  2015cites this paper
• Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell death

  2015cites this paper
• Dihydrolipoic but not alpha-lipoic acid affects susceptibility of eukaryotic cells to bacterial invasion.

  2015cites this paper
• Effect of n-3 and n-6 polyunsaturated fatty acids on lipid metabolic genes and estrogen receptor expression in MCF-7 breast cancer cells.

  2015cites this paper
• Effects of Alpha-Lipoic Acid Supplementation on Inflammatory Biomarkers and Matrix Metalloproteinase-3 in Rheumatoid Arthritis Patients

  2015cites this paper
• The effects of alpha-lipoic acid on MMP-2 and MMP-9 activities in a rat renal ischemia and re-perfusion model

  2014cites this paper
• α-Lipoic acid (α-LA) inhibits the transcriptional activity of interferon regulatory factor 1 (IRF-1) via SUMOylation.

  2014cites this paper
• The importance of 1,2-dithiolane structure in α-lipoic acid for the downregulation of cell surface β1-integrin expression of human bladder cancer cells

  2014cites this paper
• Lipoic acid and lipoic acid analogs in cancer metabolism and chemotherapy

  2014cites this paper
• Antigenotoxic effect of lipoic acid against mitomycin-C in human lymphocyte cultures

  2013cites this paper
• Lipoic acid in the prevention and treatment of inflammatory disease and cancer

  2013cites this paper
• The Anti-neoplastic Effects of Alpha-Lipoic Acid: Clinical Benefits in System Tumors besides Lung Carcinomas

  2013cites this paper
• Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells

  2013cites this paper
• α-Lipoic acid suppresses migration and invasion via downregulation of cell surface β1-integrin expression in bladder cancer cells

  2013cites this paper
• Introduction: MMPs, ADAMs/ADAMTSs research products to achieve big dream.

  2012cites this paper
• Grape seed proanthocyanidins inhibit angiogenesis via the downregulation of both vascular endothelial growth factor and angiopoietin signaling.

  2012cites this paper
• The Beneficial Effects of Nutritional Compounds on Breast Cancer Metastasis

  2011cites this paper
• Lipoic acid - biological activity and therapeutic potential

  2011cites this paper