Impaired Antibody Responses but Normal Proliferation of Specific CD4+ T Cells in Mice Lacking Complement Receptors 1 and 2

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Scandinavian Journal of Immunology

• Publication date

  2009-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1365-3083.2009.02274.xPMID 19630912
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Follicular shuttling of marginal zone B cells facilitates antigen transport

  2008cited by this paper
• A Novel B Cell-Mediated Transport of IgE-Immune Complexes to the Follicle of the Spleen1

  2008cited by this paper
• IgE Enhances Specific Antibody and T‐cell Responses in Mice Overexpressing CD23

  2007cited by this paper
• Optimal Long-Term Humoral Responses to Replication-Defective Herpes Simplex Virus Require CD21/CD35 Complement Receptor Expression on Stromal Cells

  2006cited by this paper
• Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells

  2005cited by this paper
• IgG3‐Mediated Enhancement of the Antibody Response is Normal in FcγRI‐Deficient Mice

  2005cited by this paper
• IgE Enhances Antibody and T Cell Responses In Vivo via CD23+ B Cells1

  2005cited by this paper
• The complement system in regulation of adaptive immunity

  2004cited by this paper
• IgG2a-Mediated Enhancement of Antibody and T Cell Responses and Its Relation to Inhibitory and Activating Fcγ Receptors1

  2004cited by this paper
• IgG- and IgE-mediated antigen presentation on MHC class II.

  2004cited by this paper
• Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells.

  2004cited by this paper
• A Role for Complement in Feedback Enhancement of Antibody Responses by IgG3

  2003cited by this paper
• Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses.

  2002cited by this paper
• Synergistic roles of IgM and complement in antigen trapping and follicular localization

  2002cited by this paper
• Two-Photon Imaging of Lymphocyte Motility and Antigen Response in Intact Lymph Node

  2002cited by this paper
• Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection

  2002cited by this paper
• Modeling the presentation of C3d-coated antigen by B lymphocytes: enhancement by CR1/2-BCR co-ligation is selective for the co-ligating antigen.

  2002cited by this paper
• The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts.

  2001cited by this paper
• The Role of the CD19/CD21 Complex in B Cell Processing and Presentation of Complement-Tagged Antigens

  2001cited by this paper
• Expression of Human Complement Receptor 2 (CR2, CD21) in Cr2−/− Mice Restores Humoral Immune Function1

  2000cited by this paper
• Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis.

  2000cited by this paper
• Tracing uptake of C3dg-conjugated antigen into B cells via complement receptor type 2 (CR2, CD21).

  2000cited by this paper
• Humoral Immune Responses in Cr2−/− Mice: Enhanced Affinity Maturation but Impaired Antibody Persistence1

  2000cited by this paper
• Regulation of antibody responses via antibodies, complement, and Fc receptors.

  2000cited by this paper
• Humoral Immune Responses inCr2 Mice: Enhanced Affinity Maturation but Impaired Antibody Persistence

  2000cited by this paper
• Antibody Production in Mice Deficient for Complement Receptors 1 and 2 Can Be Induced by IgG/Ag and IgE/Ag, But Not IgM/Ag Complexes1

  2000cited by this paper
• Humoral response to herpes simplex virus is complement-dependent.

  1999cited by this paper
• IgG-mediated enhancement of antibody responses is low in Fc receptor gamma chain-deficient mice and increased in Fc gamma RII-deficient mice.

  1999cited by this paper
• Efficient IgG-mediated suppression of primary antibody responses in Fcgamma receptor-deficient mice.

  1999cited by this paper
• Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response.

  1998cited by this paper
• T Cell–dependent Immune Response in C1q-deficient Mice: Defective Interferon γ Production by Antigen-specific T Cells

  1998cited by this paper
• Visualization of specific B and T lymphocyte interactions in the lymph node.

  1998cited by this paper
• Abrogation of the alternative complement pathway by targeted deletion of murine factor B.

  1997cited by this paper
• Antibody response to a T-dependent antigen requires B cell expression of complement receptors

  1996cited by this paper
• Covalent binding of C3b to tetanus toxin: influence on uptake/internalization of antigen by antigen‐specific and non‐specific B cells

  1996cited by this paper
• CD21 augments antigen presentation in immune individuals

  1996cited by this paper
• Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2.

  1996cited by this paper
• Regulation of the B cell response to T-dependent antigens by classical pathway complement.

  1996cited by this paper
• Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen.

  1996cited by this paper
• Antibodies to murine complement receptor 1 and 2 can inhibit the antibody response in vivo without inhibiting T helper cell induction.

  1995cited by this paper
• T cell-independent antigens type 2.

  1995cited by this paper
• Natural antibody and complement-mediated antigen processing and presentation by B lymphocytes.

  1994cited by this paper
• Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

  1994cited by this paper
• Modulation of mouse complement receptors 1 and 2 suppresses antibody responses in vivo.

  1991cited by this paper
• Suppression of the immune response by a soluble complement receptor of B lymphocytes.

  1991cited by this paper
• Inhibition of immunological memory and T‐independent humoral responses by monoclonal antibodies specific for murine complement receptors

  1991cited by this paper
• Effects of pH and polysaccharides on peptide binding to class II major histocompatibility complex molecules.

  1991cited by this paper
• Characterization of murine complement receptor type 2 and its immunological cross-reactivity with type 1 receptor.

  1990cited by this paper
• Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo.

  1990cited by this paper
• In vivo inhibition of the antibody response by a complement receptor- specific monoclonal antibody

  1990cited by this paper
• Complement activation is required for IgM-mediated enhancement of the antibody response

  1988cited by this paper
• Synergistic interaction between complement receptor type 2 and membrane IgM on B lymphocytes.

  1988cited by this paper
• Role of C3 in humoral immunity. Defective antibody production in C3-deficient dogs.

  1988cited by this paper
• Monoclonal antibodies to mouse complement receptor type 1 (CR1). Their use in a distribution study showing that mouse erythrocytes and platelets are CR1-negative.

  1988cited by this paper
• The role and mechanism of cobra venom factor-induced suppression of the humoral immune response in guinea pigs.

  1986cited by this paper
• Influence of genetically inherited complement deficiencies on humoral immune response in guinea pigs.

  1985cited by this paper
• The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype

  1984cited by this paper
• The role of complement in the induction of antibody responses.

  1983cited by this paper
• The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody

  1983cited by this paper
• Thirteen hybridomas secreting hapten‐specific immunoglobulin E from mice with Iga or Igb heavy chain haplotype

  1981cited by this paper
• Linkage of total deficiency of the second component (C2) of the complement system and of genetic C2-polymorphism to the major histocompatibility complex of the guinea pig.

  1981cited by this paper
• Immune response of a patient with deficiency of the fourth component of complement and systemic lupus erythematosus.

  1979cited by this paper
• Studies of immunosuppression by cobra venom factor. I. On early IgG and IgM responses to sheep erythrocytes and DNP-protein conjugates.

  1978cited by this paper
• Studies on immunosuppression by cobra venom factor. II. On responses to DNP-Ficoll and DNP-Polyacrylamide.

  1978cited by this paper
• ROLE OF COMPLEMENT IN INDUCTION OF ANTIBODY PRODUCTION IN VIVO

  1974cited by this paper

• Antibody feedback regulation

  2024cites this paper
• Endogenous complement-activating IgM is not required for primary antibody responses but promotes plasma cell differentiation and secondary antibody responses to a large particulate antigen in mice

  2024cites this paper
• IgG Suppresses Antibody Responses to Sheep Red Blood Cells in Double Knock-Out Mice Lacking Complement Factor C3 and Activating Fcγ-Receptors

  2020cites this paper
• Targeting the Immune Complex–Bound Complement C3d Ligand as a Novel Therapy for Lupus

  2019cites this paper
• IgM and Its Receptors and Binding Proteins

  2017cites this paper
• Specific IgM and Regulation of Antibody Responses.

  2017cites this paper
• IgG3 Complements IgM in the Complement-Mediated Regulation of Immune Responses

  2017cites this paper
• EBI2 augments Tfh cell fate by promoting interaction with IL2-quenching dendritic cells

  2016cites this paper
• IgG Suppresses Antibody Responses in Mice Lacking C1q, C3, Complement Receptors 1 and 2, or IgG Fc-Receptors

  2015cites this paper
• A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease.

  2015cites this paper
• IgM and Complement in Regulation of Antibody Responses

  2015cites this paper
• eview ow antibodies use complement to regulate antibody responses

  2014cites this paper
• Murine complement receptor 1 is required for germinal center B cell maintenance but not initiation.

  2014cites this paper
• How antibodies use complement to regulate antibody responses.

  2014cites this paper
• Antibodies as natural adjuvants.

  2014cites this paper
• Complement-Activating IgM Enhances the Humoral but Not the T Cell Immune Response in Mice

  2013cites this paper
• Complement C3 depletion links to the expansion of regulatory T cells and compromises T-cell immunity in human abdominal sepsis: a prospective pilot study.

  2013cites this paper
• Optimal Germinal Center B Cell Activation and T-Dependent Antibody Responses Require Expression of the Mouse Complement Receptor Cr1

  2013cites this paper
• Complement Receptor Cr 1 Require Expression of the Mouse and T-Dependent Antibody Responses Optimal Germinal Center B Cell Activation

  2013cites this paper
• Complement Receptors 1 and 2 in Murine Antibody Responses to IgM-Complexed and Uncomplexed Sheep Erythrocytes

  2012cites this paper
• Novel roles of complement in T effector cell regulation.

  2012cites this paper
• Requirement for complement in antibody responses is not explained by the classic pathway activator IgM

  2011cites this paper
• Human complement receptor type 2 (CR2/CD21) transgenic mice provide an in vivo model to study immunoregulatory effects of receptor antagonists.

  2011cites this paper
• IgM and its receptors: Structural and functional aspects

  2011cites this paper
• IgM and its receptors: Structural and functional aspects

  2011cites this paper
• IgE-Mediated Enhancement of CD4+ T Cell Responses in Mice Requires Antigen Presentation by CD11c+ Cells and Not by B Cells

  2011cites this paper