Products of the TAL1 oncogene: basic helix-loop-helix proteins phosphorylated at serine residues.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Oncogene

• Publication date

  1993-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 8437851
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Involvement of the putative hematopoietic transcription factor SCL in T-cell acute lymphoblastic leukemia.

  1992cited by this paper
• The translocation (1;14)(p34;q11) in human t‐cell leukemia: Chromosome breakage 25 kilobase pairs downstream of the tal1 protooncogene

  1992cited by this paper
• The regulation of transcription by phosphorylation.

  1992cited by this paper
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  1991cited by this paper
• Two site-specific deletions and t(1;14) translocation restricted to human T-cell acute leukemias disrupt the 5' part of the tal-1 gene.

  1991cited by this paper
• The myoD gene family: nodal point during specification of the muscle cell lineage.

  1991cited by this paper
• Rearrangements of the tal-1 locus as clonal markers for T cell acute lymphoblastic leukemia.

  1991cited by this paper
• c-tal, a helix-loop-helix protein, is juxtaposed to the T-cell receptor-beta chain gene by a reciprocal chromosomal translocation: t(1;7)(p32;q35).

  1991cited by this paper
• Transcriptional activation by heterodimers of the achaete‐scute and daughterless gene products of Drosophila.

  1991cited by this paper
• TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia.

  1991cited by this paper
• Translocations, master genes, and differences between the origins of acute and chronic leukemias.

  1991cited by this paper
• Erythroid expression of the 'helix-loop-helix' gene, SCL.

  1991cited by this paper
• The SCL gene is formed from a transcriptionally complex locus

  1990cited by this paper
• Site‐specific recombination of the tal‐1 gene is a common occurrence in human T cell leukemia.

  1990cited by this paper
• The t(1;14)(p34;q11) is nonrandom and restricted to T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.

  1990cited by this paper
• Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia

  1990cited by this paper
• Transcription factor phosphorylation: a link between signal transduction and the regulation of gene expression.

  1990cited by this paper
• The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix‐loop‐helix protein.

  1990cited by this paper
• Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity.

  1990cited by this paper
• Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T‐cell leukemias

  1990cited by this paper
• lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif.

  1989cited by this paper
• Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.

  1989cited by this paper
• Consistent breakage between consensus recombinase heptamers of chromosome 9 DNA in a recurrent chromosomal translocation of human T cell leukemia

  1989cited by this paper
• The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.

  1989cited by this paper
• Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme.

  1989cited by this paper
• A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.

  1989cited by this paper
• Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase.

  1988cited by this paper
• Peptide and protein molecular weight determination by electrophoresis using a high-molarity tris buffer system without urea.

  1986cited by this paper
• Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells

  1984cited by this paper
• The protein encoded by the human proto-oncogene c-myc.

  1984cited by this paper
• Characterization of a novel human pre-B leukemia cell line.

  1981cited by this paper

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• N-Myc and SP Regulate Phosphatidylserine Synthase-1 Expression in Brain and Glial Cells*

  2010cites this paper
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  2010cites this paper
• Mechanisms of NOTCH1 Mediated Leukemogenesis: A Dissertation

  2009cites this paper
• The Identification of Cooperating Mutations in TAL1-Mediated Leukemia in the Mouse: A Dissertation

  2005cites this paper
• Low Incidence of TALl Gene Rearrangements in Adult Acute Lymphoblastic Leukemia : A Cancer and Leukemia

  2005cites this paper
• Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia.

  2005cites this paper
• SCL: from the origin of hematopoiesis to stem cells and leukemia.

  2004cites this paper
• Mechanisms of TAL1 Induced Leukemia in Mice: A Dissertation

  2004cites this paper
• Multitasking of helix-loop-helix proteins in lymphopoiesis.

  2004cites this paper
• Clinical Features and Outcome of T-cell Acute Lymphoblastic Leukemia in Childhood With Respect to Alterations at the T A L l Locus: A Pediatric Oncology Group Study

  2003cites this paper
• Altered transcription of the stem cell leukemia gene in myelofibrosis with myeloid metaplasia

  2003cites this paper
• Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry.

  2002cites this paper
• Application of a polyaniline based ammonium sensor for the amperometric immunoassay of a urease conjugated Tal 1 protein

  2002cites this paper
• Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation.

  2002cites this paper
• Phosphorylation by Mitogen-activated Protein Kinase Mediates the Hypoxia-induced Turnover of the TAL1/SCL Transcription Factor in Endothelial Cells*

  2002cites this paper
• A novel post-transcriptional splicing form of the acute T cell leukemia proto-oncogeneLmo2

  2001cites this paper
• mSin3A Regulates Murine Erythroleukemia Cell Differentiation through Association with the TAL1 (or SCL) Transcription Factor

  2000cites this paper
• Erythroid-specific Inhibition of the tal-1 Intragenic Promoter Is Due to Binding of a Repressor to a Novel Silencer*

  2000cites this paper
• Disordered T-Cell Development and T-Cell Malignancies in SCL LMO1 Double-Transgenic Mice: Parallels with E2A-Deficient Mice

  1999cites this paper
• Growth Inhibition and Apoptosis Due to Restoration of E2A Activity in T Cell Acute Lymphoblastic Leukemia Cells

  1999cites this paper
• The SCL gene: from case report to critical hematopoietic regulator.

  1999cites this paper
• Mitogen-activated protein kinase mediates erythropoietin-induced phosphorylation of the TAL1/SCL transcription factor in murine proerythroblasts.

  1999cites this paper
• Growth Inhibition and Apoptosis Due to Restoration of E 2 A Activity in T Cell Acute Lymphoblastic Leukemia Cells

  1999cites this paper
• The stem cell leukaemia (SCL) gene: a critical regulator of haemopoietic and vascular development.

  1999cites this paper
• Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9.

  1999cites this paper
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  1998cites this paper
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  1998cites this paper
• Sequence determinants of DNA binding by the hematopoietic helix-loop-helix transcription factor TAL1: importance of sequences flanking the E-box core.

  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1997cites this paper
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  1997cites this paper
• 10 Factors involved in leukaemogenesis and haemopoiesis

  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
• AN IMMUNOHISTOCHEMICAL STUDY OF TAL‐1 PROTEIN EXPRESSION IN LEUKAEMIAS AND LYMPHOMAS WITH A NOVEL MONOCLONAL ANTIBODY, 2TL 242

  1996cites this paper
• Expression of TAL-1 proteins in human tissues.

  1995cites this paper
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  1995cites this paper
• Reconstitution of mice with bone marrow cells expressing the SCL gene is insufficient to cause leukemia.

  1995cites this paper
• Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? A pediatric oncology group study.

  1995cites this paper
• Transcription factors 2: helix-loop-helix.

  1995cites this paper
• Erythropoietin stimulates transcription of the TAL1/SCL gene and phosphorylation of its protein products

  1995cites this paper
• The role of chromosome translocations in T cell acute leukemia.

  1995cites this paper
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  1995cites this paper
• scl, a gene frequently activated in human T cell leukaemia, does not induce lymphomas in transgenic mice.

  1995cites this paper
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  1995cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
• Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells.

  1994cites this paper
• The MAP kinase phosphorylation site of TAL1 occurs within a transcriptional activation domain.

  1994cites this paper
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  1994cites this paper
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  1994cites this paper
• T-cell acute lymphoblastic leukemia and the associated basic helix-loop-helix gene SCL/tal.

  1994cites this paper
• Positive and negative transcriptional control by the TAL1 helix-loop-helix protein.

  1994cites this paper
• Expression of the TAL1 proto-oncogene in cultured endothelial cells and blood vessels of the spleen.

  1993cites this paper
• TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia.

  1993cites this paper
• Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: a Pediatric Oncology Group study.

  1993cites this paper
• Phosphorylation of the TAL1 oncoprotein by the extracellular-signal-regulated protein kinase ERK1

  1993cites this paper