OXIDATIVE MECHANISMS IN TOBACCO SMOKE-INDUCED EMPHYSEMA

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Toxicology and Environmental Health, Part A

• Publication date

  2000-09-15

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1080/00984100050116799PMID 10990164
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neutrophil recruitment and degranulation during induction of emphysema in the rat by nitrogen dioxide.

  2015cited by this paper
• Acute effect of smoking on the functional activity of alpha1-protease inhibitor in bronchoalveolar lavage fluid.

  2015cited by this paper
• Nitric Oxide I . Physiological chemistry of nitric oxide and its metabolites : implications in inflammation

  1999cited by this paper
• Effects of depletion of neutrophils or macrophages on development of cigarette smoke-induced emphysema.

  1999cited by this paper
• I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation.

  1999cited by this paper
• Superoxide mediates cigarette smoke-induced infiltration of neutrophils into the airways through nuclear factor-kappaB activation and IL-8 mRNA expression in guinea pigs in vivo.

  1999cited by this paper
• Reactive nitrogen species and tyrosine nitration in the respiratory tract: epiphenomena or a pathobiologic mechanism of disease?

  1999cited by this paper
• The oxidative inactivation of tissue inhibitor of metalloproteinase-1 (TIMP-1) by hypochlorous acid (HOCI) is suppressed by anti-rheumatic drugs.

  1998cited by this paper
• Oxidation of the Mesangial Matrix Metalloproteinase-2 Impairs Gelatinolytic Activity

  1998cited by this paper
• Matrix metalloproteinase degradation of extracellular matrix: biological consequences.

  1998cited by this paper
• Genes, oxidative stress, and the risk of chronic obstructive pulmonary disease

  1998cited by this paper
• Time course of neutrophil and macrophage elastinolytic activities in cigarette smoke-induced emphysema.

  1998cited by this paper
• Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema.

  1998cited by this paper
• Hydrolysis of a Broad Spectrum of Extracellular Matrix Proteins by Human Macrophage Elastase*

  1997cited by this paper
• Increased expression of activated matrix metalloproteinase-2 by human endothelial cells after sublethal H2O2 exposure.

  1997cited by this paper
• Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients.

  1997cited by this paper
• Activation of human neutrophil procollagenase by nitrogen dioxide and peroxynitrite: a novel mechanism for procollagenase activation involving nitric oxide.

  1997cited by this paper
• Effect of exposure of guinea pigs to cigarette smoke on elastolytic activity of pulmonary macrophages.

  1997cited by this paper
• Effects of reactive metabolites of oxygen and nitrogen on gelatinase A activity.

  1997cited by this paper
• Matrix metalloproteinase expression and production by alveolar macrophages in emphysema.

  1997cited by this paper
• Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice.

  1997cited by this paper
• Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells.

  1997cited by this paper
• Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability.

  1996cited by this paper
• Increased expression of gelatinases and collagenase in rat lungs exposed to 100% oxygen.

  1996cited by this paper
• Inactivation of tissue inhibitor of metalloproteinase‐1 by peroxynitrite

  1996cited by this paper
• Role of oxidants/antioxidants in smoking-induced lung diseases.

  1996cited by this paper
• Quartz inactivates alpha 1-antiproteinase: possible role in mineral dust-induced emphysema.

  1995cited by this paper
• Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases.

  1995cited by this paper
• Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N‐acetylcysteine

  1995cited by this paper
• Humic-like substances in cigarette smoke condensate and lung tissue of smokers.

  1994cited by this paper
• Cigarette smoking, emphysema, and damage to alpha 1-proteinase inhibitor.

  1994cited by this paper
• Ozone, but not nitrogen dioxide, fragments elastin and increases its susceptibility to proteolysis.

  1994cited by this paper
• Oxidants in Cigarette Smoke Radicals, Hydrogen Peroxide, Peroxynitrate, and Peroxynitrite a

  1993cited by this paper
• Nitrogen dioxide reactivity with proteins: effects on activity and immunoreactivity with alpha-1-proteinase inhibitor and implications for NO2-mediated peptide degradation.

  1993cited by this paper
• Different effects of hypochlorous acid on human neutrophil metalloproteinases: activation of collagenase and inactivation of collagenase and gelatinase.

  1992influential reference
• Protection by N-acetylcysteine of the histopathological and cytogenetical damage produced by exposure of rats to cigarette smoke.

  1992cited by this paper
• Oxidant-mediated inactivation of TIMP.

  1992cited by this paper
• Proteolytic inactivation of alpha 1-proteinase inhibitor and alpha 1-antichymotrypsin by oxidatively activated human neutrophil metalloproteinases.

  1992cited by this paper
• The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

  1990cited by this paper
• Ascorbic acid inhibits polymorphonuclear leukocytes influx to the place of inflammation--possible protection of lung from phagocyte-mediated injury.

  1989cited by this paper
• Elastin degradation by human alveolar macrophages. A prominent role of metalloproteinase activity.

  1989cited by this paper
• Comparison of smoker and nonsmoker lavage fluid for the rate of association with neutrophil elastase.

  1989cited by this paper
• Interactions among stimulated human polymorphonuclear leucocytes, released elastase and bronchial antileucoprotease.

  1988cited by this paper
• Interactions among stimulated human polymorphonuclear leucocytes, released elastase and bronchial antileucoprotease.

  1988cited by this paper
• Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases

  1988cited by this paper
• Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase.

  1987cited by this paper
• Enhanced chemotaxis and superoxide anion production by polymorphonuclear leukocytes from nicotine-treated and smoke-exposed rats.

  1987cited by this paper
• Degradation of human glomerular basement membrane by stimulated neutrophils. Activation of a metalloproteinase(s) by reactive oxygen metabolites.

  1987cited by this paper
• Nicotine potentiates superoxide anion generation by human neutrophils.

  1986cited by this paper
• A genetically engineered, mutant human alpha-1-proteinase inhibitor is more resistant than the normal inhibitor to oxidative inactivation by chemicals, enzymes, cells, and cigarette smoke.

  1986cited by this paper
• Effects of Cigarette Smoke Fractions on the Chemotaxis of Polymorphonuclear Leukocytes

  1986cited by this paper
• Activation of latent collagenase from polymorphonuclear leukocytes by oxygen radicals.

  1986cited by this paper
• Inhibition of mammalian collagenases by thiol‐containing peptides

  1986cited by this paper
• The role of complement in cigarette smoke-induced chemotactic activity of lung fluids.

  1986cited by this paper
• Oxidative autoactivation of latent collagenase by human neutrophils.

  1985cited by this paper
• Oxidants, antioxidants and the pathogenesis of emphysema.

  1985cited by this paper
• Cigarette smoke decreases the rate constant for the association of elastase with alpha 1-proteinase inhibitor by a non-oxidative mechanism.

  1985cited by this paper
• Cigarette smoke can activate the alternative pathway of complement in vitro by modifying the third component of complement.

  1985cited by this paper
• Effects of Nicotine on the Functions of Human Polymorphonuclear Leukocytes In Vitro

  1985cited by this paper
• Nicotine is chemotactic for neutrophils and enhances neutrophil responsiveness to chemotactic peptides.

  1984cited by this paper
• Degradation of soluble collagen by ozone or hydroxyl radicals

  1984cited by this paper
• The functional activity of alpha 1-proteinase inhibitor in bronchoalveolar lavage fluids from healthy human smokers and non-smokers.

  1983cited by this paper
• The role of oxidative processes in emphysema.

  1983cited by this paper
• Cigarette smoking and lung destruction. Accumulation of neutrophils in the lungs of cigarette smokers.

  1983cited by this paper
• Smokers do not have less functional alpha 1-protease inhibitor in their lower respiratory tracts than nonsmokers.

  1983cited by this paper
• Functional alpha 1-protease inhibitor in the lower respiratory tract of cigarette smokers is not decreased.

  1983cited by this paper
• Cigarette smoking and lung destruction: accumulation of neutrophils in the lungs of cigarette smokers

  1983cited by this paper
• The functional activity of α1-proteinase inhibitor in bronchoalveolar lavage fluids from healthy human smokers and non-smokers

  1983cited by this paper
• Reduction of the elastase inhibitory capacity of alpha 1-antitrypsin by peroxides in cigarette smoke: an analysis of brands and filters.

  1982cited by this paper
• Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity.

  1982cited by this paper
• Ozone inactivation of human alpha 1-proteinase inhibitor.

  1980cited by this paper
• Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans.

  1979cited by this paper
• Possible mechanisms of emphysema in smokers: cigarette smoke condensate suppresses protease inhibition in vitro.

  1977cited by this paper

• Secretome profiling of human epithelial cells exposed to cigarette smoke extract and their effect on human lung microvascular endothelial cells

  2024cites this paper
• The Impact of Tobacco Cigarettes, Vaping Products and Tobacco Heating Products on Oxidative Stress

  2022cites this paper
• Treatment with Bixin-Loaded Polymeric Nanoparticles Prevents Cigarette Smoke-Induced Acute Lung Inflammation and Oxidative Stress in Mice

  2022cites this paper
• More to Explore: Further Definition of Risk Factors for COPD – Differential Gender Difference, Modest Elevation in PM2.5, and e-Cigarette Use

  2021cites this paper
• Attenuation of Cigarette Smoke-Induced Emphysema in Mice by Apolipoprotein A-1 Overexpression.

  2015cites this paper
• Pathophysiology of tobacco smoke exposure: recent insights from comparative and redox proteomics.

  2014cites this paper
• Poly-Ingredient Formulation Bresol® Ameliorates Experimental Chronic Obstructive Pulmonary Disease (COPD) in Rats

  2013cites this paper
• The Relationship Between Oxidative Stress Responses and Lung Inflammation with Cigarette Smoking

  2013cites this paper
• Oxidative stress in airway diseases.

  2013cites this paper
• Exercise may offset nicotine-induced injury in lung tissue: A preliminary histological study based on a rat model

  2012cites this paper
• Hypersensitivity pneumonitis

  2012cites this paper
• The Pro-Inflammatory Contributions of Receptors for Advanced Glycation End-Products (RAGE) in Alveolar Macrophages Following Cigarette Smoke Exposure

  2012cites this paper
• Smoking and High-Fat Diet: Risk Factors Regulating Emphysema Formation

  2011cites this paper
• Simvastatin as a Modulator of Tissue Remodeling through Inhibition of Matrix Metalloproteinase (MMP) Release from Human Lung Fibroblasts

  2011cites this paper
• Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms.

  2008cites this paper
• Mate tea reduced acute lung inflammation in mice exposed to cigarette smoke.

  2008cites this paper
• Vitamin A and emphysema.

  2007cites this paper
• The Effect of Cigarette Smoke-derived Oxidants on the Inflammatory Response of the Lung.

  2006cites this paper
• The receptor for advanced glycation end products and its ligands: a new inflammatory pathway in lung disease?

  2006cites this paper
• Acute effects of environmental tobacco smoke and dried dung smoke on lung histopathology in rabbits

  2006cites this paper
• Effects of N-acetylcysteine on the lung histopathology and oxidant-antioxidant status in rabbits exposed to cigarette smoke.

  2006cites this paper
• Cigarette smoke inhibits alveolar repair: a mechanism for the development of emphysema.

  2006cites this paper
• Effects of melatonin on the oxidant/antioxidant status and lung histopathology in rabbits exposed to cigarette smoke

  2006cites this paper
• Oxidative Stress in Laboratory Animals Exposed to Cigarette Smoke, with Special Reference to Chronic Obstructive Pulmonary Disease

  2006cites this paper
• Pulmonary Effects of Cigarette Smoke in Humans

  2006cites this paper
• Superoxide dismutase expression attenuates cigarette smoke- or elastase-generated emphysema in mice.

  2006cites this paper
• Hypersensitivity Pneumonitis

  2006cites this paper
• Animal Models for Three Major Cigarette-Smoke-Induced Diseases

  2005cites this paper
• Matrix metalloproteinase/epidermal growth factor receptor/mitogen-activated protein kinase signaling regulate fra-1 induction by cigarette smoke in lung epithelial cells.

  2005cites this paper
• Calorie-related rapid onset of alveolar loss, regeneration, and changes in mouse lung gene expression.

  2004cites this paper
• DEP-induced fra-1 expression correlates with a distinct activation of AP-1-dependent gene transcription in the lung.

  2004cites this paper
• Hypersensitivity pneumonitis: a multifaceted deceiving disorder.

  2004cites this paper
• 1 DEP-induced fra-1 expression correlates with a distinct activation of AP 1-dependent gene transcription in alveolar epithelial cells

  2003cites this paper
• Nutrient Interactions and Toxicity Vitamin A Depletion Induced by Cigarette Smoke Is Associated with the Development of Emphysema in Rats 1 , 2

  2003cites this paper
• Vitamin A depletion induced by cigarette smoke is associated with the development of emphysema in rats.

  2003cites this paper
• Plasma 7-Hydroxycholesterol as a Possible Predictor of Lung Cancer Risk 1

  2002cites this paper
• FEATURED CME TOPIC: ADVERSE EFFECTS OF SMOKING

  2002cites this paper
• Role and regulation of activator protein-1 in toxicant-induced responses of the lung.

  2002cites this paper
• Plasma 7beta-hydroxycholesterol as a possible predictor of lung cancer risk.

  2002cites this paper
• Rapid Communication: URINARY THIOETHER EXCRETION AND ERYTHROCYTE GLUTATHIONE S -TRANSFERASE ACTIVITIES IN SMOKERS AND PATIENTS WITH SQUAMOUS-CELL LARYNGEAL CANCER

  2001cites this paper
• Cigarette smoke impairs neutrophil respiratory burst activation by aldehyde-induced thiol modifications.

  2001cites this paper