Elucidation of Pyranonigrin Biosynthetic Pathway Reveals a Mode of Tetramic Acid, Fused γ-Pyrone, and exo-Methylene Formation.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Organic Letters

• Publication date

  2015-09-28

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/acs.orglett.5b02435PMID 26414728
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB

  2014cited by this paper
• Generation of Complexity in Fungal Terpene Biosynthesis: Discovery of a Multifunctional Cytochrome P450 in the Fumagillin Pathway

  2014cited by this paper
• Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk.

  2013cited by this paper
• Pyranonigrin E: A PKS‐NRPS Hybrid Metabolite from Aspergillus niger Identified by Genome Mining

  2013cited by this paper
• Studies on pyranonigrins–isolation of pyranonigrin E and biosynthetic studies on pyranonigrin A

  2013cited by this paper
• Cordylactam, a new alkaloid from the spider pathogenic fungus Cordyceps sp. BCC 12671

  2013cited by this paper
• Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis.

  2013cited by this paper
• Faculty Opinions recommendation of Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk.

  2013cited by this paper
• Establishing a New Methodology for Genome Mining and Biosynthesis of Polyketides and Peptides through Yeast Molecular Genetics

  2012cited by this paper
• Complexity generation during natural product biosynthesis using redox enzymes.

  2012cited by this paper
• PKS and NRPS release mechanisms.

  2010cited by this paper
• Enzymatic processing of fumiquinazoline F: a tandem oxidative-acylation strategy for the generation of multicyclic scaffolds in fungal indole alkaloid biosynthesis.

  2010cited by this paper
• In-depth analysis of the Aspergillus niger glucoamylase (glaA) promoter performance using high-throughput screening and controlled bioreactor cultivation techniques.

  2008cited by this paper
• Highly efficient gene targeting in the Aspergillus niger kusA mutant.

  2007cited by this paper
• A Versatile and Efficient Gene-Targeting System for Aspergillus nidulans

  2006cited by this paper
• New natural products from the sponge-derived fungus Aspergillus niger.

  2004cited by this paper

• Genomic insights into the biosynthetic capacity of the sponge-associated fungus Aspergillus puulaauensis Hmp-F48

  2026cites this paper
• Genome Mining-Based Discovery of Pyrano[2,3‑c]pyrrole Type Natural Products Possessing Alkyl Side Chain with Branched Methyl Groups

  2025cites this paper
• Profiling of bioactive secondary metabolites from Aspergillus niger against a guava wilt pathogen, Fusarium oxysporum f. sp. psidii

  2024cites this paper
• Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis

  2024cites this paper
• Elucidation of chalkophomycin biosynthesis reveals N-hydroxypyrrole-forming enzymes

  2024cites this paper
• Reactive Azlactone Intermediate Drives Fungal Secondary Metabolite Cross-Pathway Generation.

  2023cites this paper
• Labelling studies in the biosynthesis of polyketides and non-ribosomal peptides.

  2022cites this paper
• Current status of secondary metabolite pathways linked to their related biosynthetic gene clusters in Aspergillus section Nigri.

  2022cites this paper
• Aspergillus niger as a Secondary Metabolite Factory

  2021cites this paper
• Comparative Transcriptomics and Gene Knockout Reveal Virulence Factors of Arthrinium phaeospermum in Bambusa pervariabilis × Dendrocalamopsis grandis

  2021cites this paper
• Biosynthesis of fungal polyketides by collaborating and trans-acting enzymes.

  2021cites this paper
• Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity.

  2021cites this paper
• Biosynthetic strategies for tetramic acid formation.

  2021cites this paper
• Alkaloids from Marine Fungi: Promising Antimicrobials

  2020cites this paper
• Fungal Polyketide-Nonribosomal Peptide Synthetases and Their Associated Natural Products

  2020cites this paper
• Heterologous- and engineered- biosynthesis of nematocidal polyketide-nonribosomal peptide hybrid macrolactone from extreme thermophilic fungi.

  2020cites this paper
• Discovery and Characterization of a PKS-NRPS Hybrid in Aspergillus terreus by Genome Mining.

  2020cites this paper
• Dehydration reactions in polyfunctional natural products.

  2020cites this paper
• Predicting the chemical space of fungal polyketides by phylogeny-based bioinformatics analysis of polyketide synthase-nonribosomal peptide synthetase and its modification enzymes

  2020cites this paper
• Discovery of Pyranoviolin A and Its Biosynthetic Gene Cluster in Aspergillus violaceofuscus

  2020cites this paper
• Genomics-directed activation of cryptic natural product pathways deciphers codes for biosynthesis and molecular function

  2020cites this paper
• Tetramic acid based alkaloids from Aspergillus amoenus Roberg strain UP197 – antibiotic properties and new pyranterreones

  2020cites this paper
• Recent advances in the genome mining of Aspergillus secondary metabolites (covering 2012-2018).

  2019cites this paper
• Research progress on fungal PKS-NRPS hybrid metabolites

  2019cites this paper
• Enzymatic Amide Tailoring Promotes Retro-Aldol Amino Acid Conversion To Form the Antifungal Agent Aspirochlorine.

  2018cites this paper
• Unstable Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum EIODSF 008

  2018cites this paper
• Enzymology of Anthraquinone-gamma-Pyrone Ring Formation in Complex Aromatic Polyketide Biosynthesis.

  2018cites this paper
• Polyketide Synthase–Nonribosomal Peptide Synthetase Hybrid Enzymes of Fungi

  2018cites this paper
• Identification of the Pyranonigrin A Biosynthetic Gene Cluster by Genome Mining in Penicillium thymicola IBT 5891.

  2018cites this paper
• Enzymatic Amide Tailoring Promotes Retro-Aldol Amino Acid Conversion To Form the Antifungal Agent Aspirochlorine

  2018cites this paper
• Enzymology of Anthraquinone-γ-Pyrone Ring Formation in Complex Aromatic Polyketide Biosynthesis.

  2018cites this paper
• Pyxipyrrolones: Structure Elucidation and Biosynthesis of Cytotoxic Myxobacterial Metabolites.

  2017cites this paper
• Die Pyxipyrrolone: Strukturaufklärung und Biosynthese zytotoxischer myxobakterieller Sekundärmetabolite

  2017cites this paper
• Structural Revision and Biosynthesis of the Fungal Phytotoxins Phyllostictines A and B.

  2017cites this paper
• Integration of Chemical, Genetic, and Bioinformatic Approaches Delineates Fungal Polyketide-Peptide Hybrid Biosynthesis.

  2017cites this paper
• Elucidation of Biosynthetic Pathways of Natural Products.

  2017cites this paper
• New natural products isolated from Metarhizium robertsii ARSEF 23 by chemical screening and identification of the gene cluster through engineered biosynthesis in Aspergillus nidulans A1145

  2016cites this paper
• Paraphaeosphaeride D and berkleasmin F, new circumventors of arbekacin resistance in MRSA, produced by Paraphaeosphaeria sp. TR-022

  2016cites this paper