The pH-dependent induction of lipid membrane ionic permeability by N-terminally lysine-substituted analogs of gramicidin A

No abstract is available for this paper.

• Publication year

  2012

• Venue

  European Biophysics Journal

• Publication date

  2012-02-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/s00249-011-0764-6PMID 22042158
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tryptophan orientations in membrane-bound gramicidin and melittin-a comparative linear dichroism study on transmembrane and surface-bound peptides.

  2011cited by this paper
• Modeling the membrane environment for membrane proteins.

  2011cited by this paper
• Channel and nonchannel forms of spin-labeled gramicidin in membranes and their equilibria.

  2011cited by this paper
• Proton-pumping mechanism of cytochrome C oxidase.

  2011cited by this paper
• Polar groups in membrane channels: consequences of replacing alanines with serines in membrane-spanning gramicidin channels.

  2010cited by this paper
• Ball and chain

  2010cited by this paper
• Gramicidin channels are internally gated.

  2010cited by this paper
• Molecular recognition at the membrane-water interface: controlling integral peptide helices by off-membrane nucleobase pairing.

  2010cited by this paper
• Double helix formation in α‐peptides: a theoretical study

  2010cited by this paper
• Low free energy barrier for ion permeation through double-helical gramicidin.

  2009cited by this paper
• Ion channels of various types induced in lipid membranes by gramicidin a derivatives carrying a cationic sequence at their C-termini

  2007cited by this paper
• Bilayer thickness and membrane protein function: an energetic perspective.

  2007cited by this paper
• Conformation and Interaction of a D,L-alternating peptide with a bilayer membrane: x-ray reflectivity, CD, and FTIR spectroscopy.

  2007cited by this paper
• Sensitized photoinactivation of minigramicidin channels in bilayer lipid membranes.

  2007cited by this paper
• Redox-regulated ion channel activity of a cysteine-containing gramicidin A analogue.

  2006cited by this paper
• Large unselective pore in lipid bilayer membrane formed by positively charged peptides containing a sequence of gramicidin A

  2005cited by this paper
• The double ππ5.6 helix of gramicidin a predominates in unsaturated lipid membranes

  2004cited by this paper
• Proton transfer in gramicidin channels is modulated by the thickness of monoglyceride bilayers.

  2003cited by this paper
• Polyanions decelerate the kinetics of positively charged gramicidin channels as shown by sensitized photoinactivation.

  2002cited by this paper
• Modifications of alamethicin ion channels by substitution of Glu-7 for Gln-7.

  2002cited by this paper
• Water permeation through gramicidin A: desformylation and the double helix: a molecular dynamics study.

  2002influential reference
• Gramicidin derivatives as membrane-based pH sensors.

  2002cited by this paper
• Bacteriorhodopsin: a high-resolution structural view of vectorial proton transport.

  2002cited by this paper
• Desformylgramicidin: a model channel with an extremely high water permeability.

  2000cited by this paper
• NMR structure of C-terminally tagged gramicidin channels.

  1999cited by this paper
• Gramicidin channel controversy — revisited

  1999cited by this paper
• Gramicidin channel controversy — the structure in a lipid environment

  1999cited by this paper
• Membrane surface-charge titration probed by gramicidin A channel conductance.

  1998cited by this paper
• Recent Advances in the High Resolution Structures of Bacterial Channels: Gramicidin A.

  1998influential reference
• The conducting form of gramicidin A is a right-handed double-stranded double helix.

  1998cited by this paper
• The effects of calcium ions on double helical forms of gramicidin

  1997cited by this paper
• High-resolution polypeptide structure in a lamellar phase lipid environment from solid state NMR derived orientational constraints.

  1997cited by this paper
• The conformational preference of gramicidin channels is a function of lipid bilayer thickness 1

  1997cited by this paper
• Voltage-dependent behavior of a "ball-and-chain" gramicidin channel.

  1997cited by this paper
• Engineering the gramicidin channel.

  1996cited by this paper
• Photodynamic inactivation of gramicidin channels:a flash-photolysis study.

  1996cited by this paper
• Structural Polymorphism of Gramicidin A Channels: Ion Conductivity and Spectral Studies

  1996influential reference
• Stabilizing effect of D-alanine2 in gramicidin channels.

  1995cited by this paper
• Design of Regulated Ion Channels Using Measurements of Cis-Trans Isomerization in Single Molecules

  1995cited by this paper
• Ion pair binding of Ca2+ and Cl- ions in micellar-packaged gramicidin A.

  1995influential reference
• [Refinement of the spatial structure of the gramicidin A ion channel].

  1994cited by this paper
• Sodium ion binding in the gramicidin A channel. Solid-state NMR studies of the tryptophan residues.

  1994cited by this paper
• High-resolution conformation of gramicidin A in a lipid bilayer by solid-state NMR.

  1993cited by this paper
• The interaction of phthalocyanine with planar lipid bilayers

  1993cited by this paper
• Formamidinium-induced dimer stabilization and flicker block behavior in homo- and heterodimer channels formed by gramicidin A and N-acetyl gramicidin A.

  1993cited by this paper
• The use of physical methods in determining gramicidin channel structure and function.

  1993cited by this paper
• The double pi pi 5.6 helix of gramicidin A predominates in unsaturated lipid membranes.

  1993influential reference
• PHOTODYNAMIC INACTIVATION OF AN ION CHANNEL: GRAMICIDIN A

  1992cited by this paper
• Model ion channels: Gramicidin and alamethicin

  1992cited by this paper
• Molecular determinants of channel function.

  1992cited by this paper
• Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues.

  1992cited by this paper
• Determination of the structure of a membrane-incorporated ion channel. Solid-state nuclear magnetic resonance studies of gramicidin A.

  1989cited by this paper
• Synthesis and channel properties of [Tau 16]gramicidin A.

  1989cited by this paper
• Three-dimensional structure at 0.86 A of the uncomplexed form of the transmembrane ion channel peptide gramicidin A.

  1988cited by this paper
• The membrane as an environment of minimal interconversion. A circular dichroism study on the solvent dependence of the conformational behavior of gramicidin in diacylphosphatidylcholine model membranes.

  1988cited by this paper
• The gramicidin pore: crystal structure of a cesium complex.

  1988cited by this paper
• Effects of calcium on the gramicidin A single channel in phosphatidylserine membranes

  1987influential reference
• 1H‐NMR study of gramicidin A transmembrane ion channel

  1985cited by this paper
• Ion Movements in Gramicidin Channels

  1984cited by this paper
• Ca2+-gramicidin A interactions and blocking effects on the ionic channel.

  1983influential reference
• Transmembrane channel activity of gramicidin A analogs: effects of modification and deletion of the amino-terminal residue.

  1979cited by this paper
• Formation of ionic channels in black lipid membranes by succinic derivatives of Gramicidin A

  1979cited by this paper
• N-acetyl gramicidin: single-channel properties and implications for channel structure.

  1979cited by this paper
• Structure of the gramicidin A channel: discrimination between the piL,D and the beta helix by electrical measurements with lipid bilayer membranes.

  1977cited by this paper
• Formation of ion channels by a negatively charged analog of gramicidin a

  1977cited by this paper
• Blocking of the gramicidin channel by divalent cations

  1977influential reference
• The conformation of gramicidin A.

  1974influential reference
• The Gramicidin A Transmembrane Channel: A Proposed π(L,D) Helix

  1971cited by this paper
• The gramicidin A transmembrane channel: a proposed pi(L,D) helix.

  1971cited by this paper
• Thickness dependence in the action of gramicidin A on lipid bilayers.

  1971cited by this paper
• METHODS FOR THE FORMATION OF SINGLE BIMOLECULAR LIPID MEMBRANES IN AQUEOUS SOLUTION

  1963influential reference

• Cholesterol Attenuates the Pore-Forming Capacity of CARC-Containing Amphipathic Peptides

  2025cites this paper
• Function Investigations and Applications of Membrane Proteins on Artificial Lipid Membranes

  2023cites this paper
• Effect of Site-Specific Intermolecular Lysine–Tryptophan Interactions on the Aggregation of Gramicidin-Based Peptides Leading to Pore Formation in Lipid Membranes

  2018cites this paper
• pH-Dependent properties of ion channels formed by N-terminally glutamate substituted gramicidin A in planar lipid bilayers.

  2017cites this paper
• Gramicidin A disassembles large conductive clusters of its lysine-substituted derivatives in lipid membranes.

  2015cites this paper
• Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery

  2014cites this paper
• Conformation of gramicidin A in Triton X‐100 micelles from CD and FTIR data: a clean example of antiparallel double β5.6 helix formation

  2013cites this paper
• Peptide-induced membrane leakage by lysine derivatives of gramicidin A in liposomes, planar bilayers, and erythrocytes.

  2013cites this paper
• N-Terminally Glutamate-Substituted Analogue of Gramicidin A as Protonophore and Selective Mitochondrial Uncoupler

  2012cites this paper
• Mutants de la gramicidine a à activité antibiotique présentant une solubilité améliorée et une toxicité réduite

  2012cites this paper