Quantitation of mRNAs specific for the mixed-function oxidase system in rat liver and extrahepatic tissues during development.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Archives of Biochemistry and Biophysics

• Publication date

  1989-05-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0003-9861(89)90250-6PMID 2469391
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids. Transcriptional and post-transcriptional regulation.

  1987cited by this paper
• Rat testosterone 7 alpha-hydroxylase. Isolation, sequence, and expression of cDNA and its developmental regulation and induction by 3-methylcholanthrene.

  1987cited by this paper
• Induction of different isozymes of cytochrome P-450 and of microsomal epoxide hydrolase in rat liver by 2-acetylaminofluorene and structurally related compounds.

  1986cited by this paper
• Regulation of cytochrome P-450b and P-450e mRNA expression in the developing rat. Hybridization to synthetic oligodeoxyribonucleotide probes.

  1986cited by this paper
• An example of P-450 catalytic activities not correlated with corresponding P-450 mRNA concentrations.

  1986cited by this paper
• Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation

  1986cited by this paper
• Complete cDNA and protein sequence of a pregnenolone 16 alpha-carbonitrile-induced cytochrome P-450. A representative of a new gene family.

  1985cited by this paper
• Cytochrome P-450 metabolic activity in embryonic and extraembryonic tissue lineages of mouse embryos.

  1985cited by this paper
• Disappearance of sex difference in rat liver drug metabolism in old age.

  1985cited by this paper
• Synthesis and degradation of 3-methylcholanthrene-inducible cytochromes P-450 and their mRNAs in primary monolayer cultures of adult rat hepatocytes.

  1985cited by this paper
• Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes.

  1985cited by this paper
• Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes.

  1985cited by this paper
• Age- and sex-dependent induction of liver microsomal benzo[a]pyrene hydroxylase activity in rats treated with pregnenolone-16 alpha-carbonitrile (PCN).

  1985cited by this paper
• Age- and sex-dependent induction of liver microsomal benzo[a]pyrene hydroxylase activity in rats treated with pregnenolone-16α-carbonitrile (PCN)

  1985cited by this paper
• Age-related changes in the activities of epoxide hydrolases in different tissues of mice.

  1985cited by this paper
• Characterization and endocrine regulation of the cytochrome P-450 dependent microsomal hydroxylation of 5 alpha-androstane-3 beta,17 beta-diol in the rat ventral prostate.

  1984cited by this paper
• Characterization and Endocrine Regulation of the Cytochrome P-450 Dependent Microsomal Hydroxylation of 5α-Androstane-3β,17β-Diol in the Rat Ventral Prostate

  1984cited by this paper
• Induction of mRNA coding for phenobarbital-inducible form of microsomal cytochrome P-450 in rat liver by administration of 1,1-Di(p-chlorophenyl)-2,2-dichloroethylene and phenobarbital.

  1984cited by this paper
• Different patterns of developmental toxicity in the rat following prenatal administration of structurally diverse chemicals.

  1984cited by this paper
• Localization of epoxide-metabolizing enzymes in rat testis.

  1984cited by this paper
• Turnover of membrane proteins: kinetics of induction and degradation of seven forms of rat liver microsomal cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydrolase.

  1984cited by this paper
• Induction of cytochrome P-450 mRNAs quantitated by in vitro translation and immunoprecipitation.

  1984cited by this paper
• Perinatal development of styrene monooxygenase and epoxide hydrolase in rat liver microsomes and nuclei.

  1983cited by this paper
• Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone-16 alpha-carbonitrile. Characterization of its mRNA, gene, and induction response.

  1983cited by this paper
• Turnover of two drug-inducible forms of microsomal cytochrome P-450 in rat liver.

  1983cited by this paper
• The in vivo turnover of rat liver microsomal epoxide hydrolase and both the apoprotein and heme moieties of specific cytochrome P-450 isozymes.

  1983cited by this paper
• Genetic polymorphisms for a phenobarbital-inducible cytochrome P-450 map to the Coh locus in mice.

  1983cited by this paper
• Transcriptional regulation of rat liver epoxide hydratase, NADPH-Cytochrome P-450 oxidoreductase, and cytochrome P-450b genes by phenobarbital.

  1983cited by this paper
• A cytochrome P-450 multigene family. Characterization of a gene activated by phenobarbital administration.

  1983cited by this paper
• Microsomal electron-transport reductase activities and fatty acid elongation in rat brain. Developmental changes, regional distribution and comparison with liver activity.

  1983cited by this paper
• Coordinate induction of multiple mRNAs specific for rat liver phenobarbital-inducible cytochromes P-450.

  1983cited by this paper
• The influence of in vitro procedures which diminish NADPH cytochrome c reductase activity on oxidative drug metabolism in lung and liver microsomes.

  1983cited by this paper
• Multiplicity of deoxyribonucleic acid sequences with homology to a cloned complementary deoxyribonucleic acid coding for rat phenobarbital-inducible cytochrome P-450.

  1983cited by this paper
• The expression of alpha-fetoprotein and albumin genes in rat liver during chemical carcinogenesis.

  1982cited by this paper
• Cloning of DNA complementary to rat liver NADPH-cytochrome c (P-450) oxidoreductase and cytochrome P-450b mRNAs. Evidence that phenobarbital augments transcription of specific genes.

  1982cited by this paper
• Differential inducibility of nuclear envelope epoxide hydratase by trans-stilbene oxide and phenobarbital.

  1982cited by this paper
• No evidence for post-transcriptional control of albumin and alpha-fetoprotein gene expression in developing rat liver neoplasia.

  1982cited by this paper
• Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

  1982cited by this paper
• No evidence for post-transcriptional control of albumin and α-fetoprotein gene expression in developing rat liver and neoplasis

  1982cited by this paper
• The expression of α-fetoprotein and albumin genes in rat liver during chemical carcinogenesis

  1982cited by this paper
• Structure and function of rat liver polysome populations. I. Complexity, frequency distribution, and degree of uniqueness of free and membrane-bound polysomal polyadenylate-containing RNA populations

  1981cited by this paper
• Developmental onset of mixed-function oxidase activity in preimplantation mouse embryos.

  1981cited by this paper
• Cloning of epoxide hydratase complementary DNA.

  1981cited by this paper
• Sequential translocation of two phenobarbital-induced polysomal messenger ribonucleic acids from the nuclear envelope to the endoplasmic reticulum.

  1981cited by this paper
• Induction of cytochrome P-450 by pregnenolone-16 alpha-carbonitrile in primary monolayer cultures of adult rat hepatocytes and in a cell-free translation system.

  1981cited by this paper
• Extrahepatic metabolism of drugs and other foreign compounds

  1980cited by this paper
• In vitro translation of epoxide hydratase messenger RNA.

  1980cited by this paper
• Phenobarbital induction of NADPH-cytochrome c (P-450) oxidoreductase messenger ribonucleic acid.

  1980cited by this paper
• Changes in rat alpha 1-fetoprotein and albumin mRNA levels during fetal and neonatal development.

  1980cited by this paper
• Effect of microsomal preparations and induction on cytochrome P-450-dependent monooxygenases in fetal and neonatal rat liver.

  1979cited by this paper
• Immunological comparison of hepatic and extrahepatic cytochromes P-450.

  1979cited by this paper
• Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

  1979cited by this paper
• Immunological and biochemical characterization of nuclear envelope reduced nicotinamide adenine dinucleotide phosphate-cytochrome c oxidoreductase.

  1978cited by this paper
• Preparation and properties of highly purified cytochrome p-450 and NADPH-cytochrome P-450 reductase from pulmonary microsomes of untreated rabbits.

  1977cited by this paper
• Differential control of rat microsomal "aryl hydrocarbon" monooxygenase and epoxide hydratase.

  1976cited by this paper
• Microsomes and drug oxidations

  1968cited by this paper
• Studies on free and membrane-bound ribosomes in rat liver. I. Distribution as related to total cellular RNA.

  1967cited by this paper

• Brain Morphogenesis and Developmental Neurotoxicology

  2018cites this paper
• 14.03 – Renal Xenobiotic Metabolism☆

  2018cites this paper
• Chapter 11 – Development of Antioxidant and Xenobiotic Metabolizing Enzyme Systems

  2014cites this paper
• Age-Specific Difference in Pulmonary Cellular Injury and Mitochondrial Damage

  2014cites this paper
• Induction of cytochrome P450 3A1 expression by diallyl disulfide: protective effects against cyclophosphamide-induced embryo-fetal developmental toxicity.

  2014cites this paper
• Renal Xenobiotic Metabolism

  2010cites this paper
• Pulmonary Developmental Responses to Toxicants

  2010cites this paper
• Role of NADPH-Cytochrome P450 Reductase and Cytochrome-b5/NADH-b5 Reductase in Variability of CYP3A Activity in Human Liver Microsomes

  2009cites this paper
• The P450 oxidoreductase, RedA, controls development beyond the mound stage in Dictyostelium discoideum

  2008cites this paper
• DRUG MILK TO SERUM RATIO PREDICTION AND ONTOGENY OF CYP3A CLEARANCE PATHWAY AS A MODEL OF DRUG EXPOSURE IN THE DEVELOPING RAT

  2007influential citation
• Induction of cytochrome P450 isozymes by phenobarbital in pregnant rat and fetal livers and placenta.

  2005cites this paper
• Microarray analysis on CYPs expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile and phenobarbital.

  2005cites this paper
• Age-Related Differences in CYP3A Expression and Activity in the Rat Liver, Intestine, and Kidney

  2004cites this paper
• Development of Antioxidant and Xenobiotic Metabolizing Enzyme Systems

  2004cites this paper
• Evaluation of 2-Year-Old Intrasplenic Fetal Liver Tissue Transplants in Rats

  2003cites this paper
• Induction of CYP3A1 by dexamethasone and pregnenolone-16alpha-carbonitrile in pregnant rat and fetal livers and placenta.

  2003cites this paper
• Effect of ginseng extracts on the gene expression of hepatic drug-metabolizing enzymes in rats

  2003cites this paper
• Synthesis, Enzyme Localization, and Regulation of Neurosteroids

  2003cites this paper
• Quantification of G6PD in small and large intestine of rat during aging.

  2002cites this paper
• Caracterização do mutante de desenvolvimento redA de Dictyostelium discoideum

  2002cites this paper
• Biosynthesis of neurosteroids and regulation of their synthesis.

  2001cites this paper
• Glucose-6-phosphate dehydrogenase in small intestine of rabbit: biochemical properties and subcellular localization.

  2001cites this paper
• Expression of cytochrome P450 (CYP) isozymes in rat placenta through pregnancy.

  2001cites this paper
• Neurosteroids: biosynthesis and function of these novel neuromodulators.

  2000cites this paper
• Development of phase II xenobiotic metabolizing enzymes in differentiating murine clara cells.

  2000cites this paper
• Effect of in utero and postnatal exposure to environmental tobacco smoke on the developmental expression of pulmonary cytochrome P450 monooxygenases

  2000cites this paper
• The expression and regulation of drug metabolism in human placenta.

  1999cites this paper
• Molecular Biology and Developmental Regulation of the Enzymes Involved in the Biosynthesis and Metabolism of Neurosteroids

  1999cites this paper
• Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.

  1999cites this paper
• Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney

  1999cites this paper
• Age-dependent change of metabolic capacity and genotoxic injury in rat intestine.

  1998cites this paper
• Renal drug metabolism.

  1998cites this paper
• Nuclear Receptor Involvement in the Regulation of Rat Cytochrome P450 3A23 Expression*

  1998cites this paper
• Expression of multiple forms of cytochrome P450 and associated mono-oxygenase activities in rat brain regions.

  1998cites this paper
• Expression and inducibility of P450 enzymes during liver ontogeny

  1997cites this paper
• Low-level m-Xylene inhalation alters pulmonary and hepatic cytochrome P-450 activity in the rat.

  1996cites this paper
• Biotransformation of Drugs and other Xenobiotics during Postnatal development

  1996cites this paper
• Developmental changes in hepatic activation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in rabbit.

  1996cites this paper
• Possible mechanism for late gestational development of the antioxidant enzymes in the fetal rat lung.

  1996cites this paper
• Xenobiotic metabolism in brain.

  1995cites this paper
• Pulmonary cytochrome P-450 monooxygenase system and Clara cell differentiation in rats.

  1995cites this paper
• Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis.

  1995cites this paper
• Purification and characterization of dog liver microsomal epoxide hydrolase.

  1994cites this paper
• Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver.

  1994cites this paper
• Developmental expression of human microsomal epoxide hydrolase.

  1994cites this paper
• The expression and environmental regulation of P450 enzymes in human placenta.

  1994cites this paper
• A novel P450 expressed at the high level in rat brain.

  1993cites this paper
• Prostaglandin G/H synthase isoenzyme 2 expression in fibroblasts: regulation by dexamethasone, mitogens, and oncogenes.

  1993cites this paper
• Cytochrome P-450-dependent biotransformation of QA 208-199 in cultured rat conceptuses.

  1993cites this paper
• Ontogenetic development of the distribution of constitutive and 3-methylcholanthrene-induced CYP1A1 and CYP1A2 in rabbit liver.

  1993cites this paper
• Postnatal changes in the expression and distribution of pulmonary cytochrome P450 monooxygenases during Clara cell differentiation in rabbits.

  1993cites this paper
• Protein and Gene Structure and Regulation of NADPH-Cytochrome P450 Oxidoreductase

  1993cites this paper
• Avian Cytochrome P450

  1993cites this paper
• Tissue-specific expression, induction, and inhibition through metabolic intermediate-complex formation of guinea pig cytochrome P450 belonging to the CYP2B subfamily.

  1992cites this paper
• Studies on the developmental and adrenal regulation of cytosolic and microsomal epoxide hydrolase activities in rat liver.

  1992cites this paper
• Identification of an early-growth-response gene encoding a novel putative protein kinase

  1992cites this paper
• Gender-related expression of rat microsomal epoxide hydrolase during maturation: post-transcriptional regulation.

  1992cites this paper
• A markedly diminished pleiotropic response to phenobarbital and structurally-related xenobiotics in Zucker rats in comparison with F344/NCr or DA rats.

  1992cites this paper
• Tissue-specific induction of the carcinogen inducible cytochrome P450 isoform, P450IAI, in colonic epithelium.

  1991cites this paper
• Developmental aspects of experimental pulmonary oxygen toxicity.

  1991cites this paper
• Cytochrome P450-dependent bioactivation of prodysmorphogens in cultured conceptuses.

  1991cites this paper
• Small intestinal cytochromes P450.

  1991cites this paper
• Reproductive Biology and Endocrinology Regulation of P450 Oxidoreductase by Gonadotropins in Rat Ovary and Its Effect on Estrogen Production

  year unknowncites this paper