Reversible sarcopenia in patients with gastrointestinal stromal tumor treated with imatinib

F. Moryoussef,M. Dhooge,J. Volet,C. Barbe,C. Brézault,C. Hoeffel,R. Coriat,O. Bouché

Published 2015 in Journal of Cachexia, Sarcopenia and Muscle

ABSTRACT

Imatinib is a long‐term, oral, targeted therapy for high‐risk resected and advanced gastrointestinal stromal tumours (GIST). It is known that sarcopenia affects prognosis and treatment tolerance in patients with various solid cancers. We analysed lumbar skeletal muscle index changes in imatinib‐treated GIST patients. Imatinib tolerance was also assessed to evaluate the influence of pre‐treatment sarcopenia.

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