Pathway analysis supports association of nonsyndromic cryptorchidism with genetic loci linked to cytoskeleton-dependent functions.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Human Reproduction

• Publication date

  2015-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/humrep/dev180PMID 26209787PMCID PMC4573451
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Isolated Cryptorchidism: No Evidence for Involvement of Genes Underlying Idiopathic Hypogonadotropic Hypogonadism

  2017cited by this paper
• Phenotype specific association of the TGFBR3 locus with nonsyndromic cryptorchidism.

  2015cited by this paper
• Cryptorchidism: a clinical perspective.

  2014cited by this paper
• Cryptorchidism in the Orl Rat Is Associated with Muscle Patterning Defects in the Fetal Gubernaculum and Altered Hormonal Signaling1

  2014cited by this paper
• Increased gene copy number of the vesicle SNARE VAMP7 disrupts human male urogenital development through altered estrogen action

  2014cited by this paper
• Formin 1 and filamin B physically interact to coordinate chondrocyte proliferation and differentiation in the growth plate.

  2014cited by this paper
• CLINICAL AND RADIOLOGICAL EVALUATION OF TER HAAR SYNDROME: CASE REPORT OF A PATIENT WITH EXTREME LONGEVITY

  2014cited by this paper
• Genome-wide association analyses identify variants in developmental genes associated with hypospadias

  2014cited by this paper
• Genitourinary Defects Associated with Genomic Deletions in 2p15 Encompassing OTX1

  2014cited by this paper
• Hic-5 influences genomic and non-genomic actions of the androgen receptor in prostate myofibroblasts.

  2014cited by this paper
• The actin cytoskeleton in rapid steroid hormone actions

  2014cited by this paper
• Shorter anogenital distance correlates with undescended testis: a detailed genital anthropometric analysis in human newborns.

  2013cited by this paper
• Anogenital Distance and Penile Length in Infants with Hypospadias or Cryptorchidism: Comparison with Normative Data

  2013cited by this paper
• Transcriptome Analysis of the Dihydrotestosterone-Exposed Fetal Rat Gubernaculum Identifies Common Androgen and Insulin-Like 3 Targets1

  2013cited by this paper
• GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications

  2013cited by this paper
• Testosterone promotes vascular endothelial cell migration via upregulation of ROCK-2/moesin cascade

  2013cited by this paper
• Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

  2012cited by this paper
• Topological Domains in Mammalian Genomes Identified by Analysis of Chromatin Interactions

  2012cited by this paper
• Cryptorchidism and endocrine disrupting chemicals.

  2012cited by this paper
• Identification of a Novel LXXLL Motif in α-Actinin 4-spliced Isoform That Is Critical for Its Interaction with Estrogen Receptor α and Co-activators*

  2012cited by this paper
• Altered infant feeding patterns in boys with acquired nonsyndromic cryptorchidism.

  2012cited by this paper
• Boys with undescended testes: endocrine, volumetric and morphometric studies on testicular function before and after orchidopexy at nine months or three years of age.

  2012cited by this paper
• The androgen receptor gene mutations database: 2012 update

  2012cited by this paper
• Cryptorchidism in mice with an androgen receptor ablation in gubernaculum testis.

  2012cited by this paper
• Frank-ter Haar Syndrome Protein Tks4 Regulates Epidermal Growth Factor-dependent Cell Migration*

  2012cited by this paper
• Identification of a novel LXXLL motif in alpha actinin 4 (ACTN4) spliced isoform that is critical for its interaction with estrogen receptor alpha and co-activators

  2012cited by this paper
• A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation

  2011cited by this paper
• Suppression of insulin-like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development.

  2011cited by this paper
• Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A Association

  2011cited by this paper
• Isolated cryptorchidism: no evidence for involvement of genes underlying isolated hypogonadotropic hypogonadism.

  2011cited by this paper
• The Homolog of the Five SH3-Domain Protein (HOFI/SH3PXD2B) Regulates Lamellipodia Formation and Cell Spreading

  2011cited by this paper
• Genotype Imputation with Thousands of Genomes

  2011cited by this paper
• Common variants in DGKK are strongly associated with risk of hypospadias

  2011cited by this paper
• i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study

  2010cited by this paper
• Analysing biological pathways in genome-wide association studies

  2010cited by this paper
• Insulin-Like 3 Exposure of the Fetal Rat Gubernaculum Modulates Expression of Genes Involved in Neural Pathways1

  2010cited by this paper
• Data quality control in genetic case-control association studies

  2010cited by this paper
• Cryptorchidism concordance in monozygotic and dizygotic twin brothers, full brothers, and half-brothers.

  2010cited by this paper
• The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation.

  2009cited by this paper
• Gene expression alterations in cryptorchid males using spermatozoal microarray analysis.

  2009cited by this paper
• A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

  2009cited by this paper
• Familial aggregation of cryptorchidism--a nationwide cohort study.

  2008cited by this paper
• Formin 1-Isoform IV Deficient Cells Exhibit Defects in Cell Spreading and Focal Adhesion Formation

  2008cited by this paper
• Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

  2008cited by this paper
• Analysis of five single nucleotide polymorphisms in the ESR1 gene in cryptorchidism.

  2008cited by this paper
• Familial risks for common diseases: etiologic clues and guidance to gene identification.

  2008cited by this paper
• Altered expression of muscle- and cytoskeleton-related genes in a rat strain with inherited cryptorchidism.

  2008cited by this paper
• Role of hormones, genes, and environment in human cryptorchidism.

  2008cited by this paper
• Genetic alterations associated with cryptorchidism.

  2008cited by this paper
• Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

  2008cited by this paper
• Molecular analysis of estrogen receptor alpha gene AGATA haplotype and SNP12 in European populations: potential protective effect for cryptorchidism and lack of association with male infertility.

  2007cited by this paper
• Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive tfm mouse testis.

  2007cited by this paper
• Allelic variants in HOX genes in cryptorchidism.

  2007cited by this paper
• Surgical treatment of unilaterally undescended testes: testicular growth after randomization to orchiopexy at age 9 months or 3 years.

  2007cited by this paper
• Identification of Putative Androgen Receptor Interaction Protein Modules

  2007cited by this paper
• PLINK: a tool set for whole-genome association and population-based linkage analyses.

  2007cited by this paper
• Testicular growth from birth to two years of age, and the effect of orchidopexy at age nine months: A randomized, controlled study

  2006cited by this paper
• Vav3, a Rho GTPase guanine nucleotide exchange factor, increases during progression to androgen independence in prostate cancer cells and potentiates androgen receptor transcriptional activity.

  2006cited by this paper
• Standardized Subsets of the HGDP‐CEPH Human Genome Diversity Cell Line Panel, Accounting for Atypical and Duplicated Samples and Pairs of Close Relatives

  2006cited by this paper
• Association of cryptorchidism with a specific haplotype of the estrogen receptor alpha gene: implication for the susceptibility to estrogenic environmental endocrine disruptors.

  2005cited by this paper
• Endogenous Coactivator ARA70 Interacts with Estrogen Receptor α (ERα) and Modulates the Functional ERα/Androgen Receptor Interplay in MCF-7 Cells*

  2005cited by this paper
• Actin monomer enhances supervillin-modulated androgen receptor transactivation.

  2004cited by this paper
• Homeobox HOXA10 Gene Analysis in Cryptorchidism

  2004cited by this paper
• Further delineation of Frank–ter Haar syndrome

  2004cited by this paper
• The enhancement of nuclear receptor transcriptional activation by a mouse actin-binding protein, alpha actinin 2.

  2004cited by this paper
• A diminished postnatal surge of Ad spermatogonia in cryptorchid infants is additional evidence for hypogonadotropic hypogonadism.

  2004cited by this paper
• Effects of selective estrogen receptor modulators (SERMs) on coactivator nuclear receptor (NR) box binding to estrogen receptors.

  2002cited by this paper
• The role of insulin 3, testosterone, Müllerian inhibiting substance and relaxin in rat gubernacular growth.

  2002cited by this paper
• Analysis of homeobox gene HOXA10 mutations in cryptorchidism.

  1999cited by this paper
• The androgen receptor gene mutations database

  1996cited by this paper
• Journal of Steroid Biochemistry and Molecular Biology Actin Associated Proteins Function as Androgen Receptor Coregulators: an Implication of Androgen Receptor's Roles in Skeletal Muscle

  year unknowncited by this paper
• Printed in U.S.A. Copyright © 2000 by The Endocrine Society Hormonal Control of Gubernaculum Development during Testis Descent: Gubernaculum Outgrowth in Vitro Requires Both Insulin-Like Factor and Androgen*

  year unknowncited by this paper

• Novel mutation leading to splice donor loss in a conserved site of DMD causes cryptorchidism

  2024cites this paper
• Novel mutation leading to splice donor loss in a conserved site of DMD gene causes Duchenne muscular dystrophy with cryptorchidism

  2024cites this paper
• Whole-Exome Sequencing Indicated New Candidate Genes Associated with Unilateral Cryptorchidism in Pigs

  2023influential citation
• Genetics of cryptorchidism and testicular regression.

  2022cites this paper
• Clinical Profiles and Genetic Spectra of 814 Chinese Children With Short Stature

  2021cites this paper
• Transcriptomic Analysis of Testicular Gene Expression in Normal and Cryptorchid Horses

  2020cites this paper
• Insulin-Like Peptide 3 (INSL3) Serum Concentration During Human Male Fetal Life

  2019cites this paper
• Study of Ras/MAPK pathway gene variants in Chilean patients with Cryptorchidism

  2018cites this paper
• Subphenotype meta-analysis of testicular cancer genome-wide association study data suggests a role for RBFOX family genes in cryptorchidism susceptibility

  2018cites this paper
• GENETIC ASPECTS OF TESTICULAR DYSGENESIS SYNDROME AND ASSOCIATED CONDITIONS

  2018cites this paper
• Perspective: A Neuro-Hormonal Systems Approach to Understanding the Complexity of Cryptorchidism Susceptibility

  2018cites this paper
• Genome-wide screening for smallest regions of overlaps in cryptorchidism.

  2018cites this paper
• Molecular Mechanisms of Syndromic Cryptorchidism: Data Synthesis of 50 Studies and Visualization of Gene-Disease Network

  2018cites this paper
• Genetic analysis of HOXA11 gene in Chinese patients with cryptorchidism

  2018cites this paper
• Risk factors for cryptorchidism

  2017cites this paper
• Exomic and Epigenomic Analyses in a Pair of Monozygotic Twins Discordant for Cryptorchidism

  2017cites this paper
• Copy number variants of Ras/MAPK pathway genes in patients with isolated cryptorchidism

  2017cites this paper
• A Case–Control Study of Maternal Polybrominated Diphenyl Ether (PBDE) Exposure and Cryptorchidism in Canadian Populations

  2017cites this paper
• Causal Factors of Cryptorchidism and Endocrine Disurpting Chemicals Such as Prenatal Maternal Cigarette Smoke: A Narrative Review

  2016influential citation
• Genetic, Maternal, and Environmental Risk Factors for Cryptorchidism: An Update

  2016cites this paper
• Polygenic inheritance of cryptorchidism susceptibility in the LE/orl rat.

  2016cites this paper
• Genomic copy number variation association study in Caucasian patients with nonsyndromic cryptorchidism

  2016influential citation
• Molecular mechanisms of cryptorchidism development: update of the database, disease comorbidity, and initiative for standardization of reporting in scientific literature

  2016cites this paper