Model Organisms as Models: Understanding the 'Lingua Franca' of the Human Genome Project

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Philosophia Scientiæ

• Publication date

  2001-09-01

• Fields of study

  Sociology, Philosophy, Linguistics

• Identifiers
  DOI 10.1086/392913
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Brute Science

  2020cited by this paper
• Initial sequencing and analysis of the human genome

  2001cited by this paper
• The Sequence of the Human Genome

  2001cited by this paper
• Philosophy of Biology, Psychology, and Neuroscience-The Organism in Philosophical Focus-Fashioning Descriptive Models in Biology: Of Worms and Wiring Diagrams

  2000cited by this paper
• A diverse approach to arthropod development

  2000cited by this paper
• Mouse Sequencers Take Up the Shotgun

  2000cited by this paper
• Fruit Fly Genome Yields Data and a Validation

  2000cited by this paper
• Of Mice, Medicine, and Genetics: C. C. Little's Creation of the Inbred Laboratory Mouse, 1909–1918

  1999cited by this paper
• New goals for the U.S. Human Genome Project: 1998-2003.

  1998cited by this paper
• Model Organisms and Behavioral Genetics: A Rejoinder

  1998cited by this paper
• Of worms and programmes: Caenorhabditis elegans and the study of development

  1998cited by this paper
• “The Mouse People”: Murine Genetics Work at the Bussey Institution, 1909–1936

  1998cited by this paper
• The complete genome sequence of Escherichia coli K-12.

  1997cited by this paper
• Life Before Model Systems: General Zoology at August Weismann's Institute

  1997cited by this paper
• Life with 6000 Genes

  1996cited by this paper
• Realism Rescued: How Scientific Progress Is Possible

  1995cited by this paper
• Model systems in developmental biology

  1995cited by this paper
• A molecular evolutionary framework for eukaryotic model organisms.

  1994cited by this paper
• Lords of the fly: Drosophila genetics and the experimental life.

  1994cited by this paper
• Discovery and Explanation in Biology and Medicine

  1994cited by this paper
• A new five-year plan for the U.S. Human Genome Project.

  1993cited by this paper
• How the choice of experimental organism matters: Epistemological reflections on an aspect of biological practice

  1993cited by this paper
• The Wistar rat as a right choice: Establishing mammalian standards and the ideal of a standardized mammal

  1993influential reference
• The “light” organism for the job: Green algae and photosynthesis research

  1993cited by this paper
• The old martyr of science: The frog in experimental physiology

  1993cited by this paper
• MODEL ORGANISMS IN EVOLUTIONARY STUDIES

  1993cited by this paper
• 1. What Tools? Which Jobs? Why Right?

  1992cited by this paper
• Systems of Production: Drosophila, Neurospora, and Biochemical Genetics

  1991cited by this paper
• Orchestrating the Human Genome Project.

  1990cited by this paper
• The Neglect of Experiment

  1986cited by this paper
• Sequence the Human Genome

  1986cited by this paper
• Exemplar reasoning about biological models and diseases: a relation between the philosophy of medicine and philosophy of science.

  1986cited by this paper
• Representing and Intervening

  1985cited by this paper
• Representing and Intervening: Introductory Topics in the Philosophy of Natural Science

  1983cited by this paper
• Scientific Books: Les Physiciens Hollandais et la Methode Experimental en France au XVIIIeme Siecle; An Introduction to the Study of Experimental Medicine

  year unknowncited by this paper

• How transdisciplinarity can help biotech-driven biodiversity research.

  2025cites this paper
• Extrapolating animal consciousness.

  2024cites this paper
• Animal Models of Human Disease

  2024cites this paper
• Lampreys and spinal cord regeneration: “a very special claim on the interest of zoologists,” 1830s-present

  2023cites this paper
• Ratifying frailty.

  2022cites this paper
• A concrete example of representational licensing: The Mississippi River Basin Model.

  2022cites this paper
• Problemas contemporáneos en la filosofía de la bioquímica

  2022cites this paper
• In Defence of an Inferential Account of Extrapolation

  2021cites this paper
• How interventionist accounts of causation work in experimental practice and why there is no need to worry about supervenience

  2021cites this paper
• Response to Alexander and Weinberg,  Baz and Deutsch By Edouard Machery

  2021cites this paper
• Representation-supporting model elements

  2020cites this paper
• Advancing Science while Training Undergraduates: Recommendations from a Collaborative Biology Research Network

  2020cites this paper
• Performative Epistemology and the Philosophy of Experimental Biology: A Synoptic Overview

  2020cites this paper
• Mechanisms in Molecular Biology

  2019cites this paper
• Yeast: one cell, one reference sequence, many genomes?

  2019cites this paper
• Model Organisms as Simulators: The Context of Cross-Species Research and Emergence

  2019cites this paper
• Model Organisms as Simulators: The Context of Cross-Species Research and Emergence

  2019cites this paper
• The Bermuda Triangle: The Pragmatics, Policies, and Principles for Data Sharing in the History of the Human Genome Project

  2018cites this paper
• Que font les scientifiques lorsqu’ils ne sont pas naturalistes ?. Le cas des levuristes

  2017cites this paper
• Reconceiving the New World Order: Genes, Reproduction, and the Politics of Regenerative Medicine

  2017cites this paper
• Trust in Science: CRISPR–Cas9 and the Ban on Human Germline Editing

  2017cites this paper
• On pain experience, multidisciplinary integration and the level-laden conception of science

  2017cites this paper
• Generative models: Human embryonic stem cells and multiple modeling relations.

  2016cites this paper
• The ‘Big Picture’: The Problem of Extrapolation in Basic Research

  2016influential citation
• Extrapolation from Animal Model of Depressive Disorders: What’s Lost in Translation?

  2016cites this paper
• Articulating the World: Conceptual Understanding and the Scientific Image

  2015cites this paper
• What Salamander Biologists Have Taught Us About Evo-devo

  2015cites this paper
• Mathematizing Nature's Messiness: Graphical Representations of Variation in Ecology, 1930-present

  2015cites this paper
• BUSINESS MODELS: IDEAL TYPES, VALUES, PROFITS AND TECHNOLOGIES

  2015cites this paper
• Experimentation in Cognitive Neuroscience and Cognitive Neurobiology

  2015cites this paper
• Generalizing Mechanistic Explanations Using Graph-Theoretic Representations

  2015cites this paper
• Publication Trends in Model Organism Research

  2014cites this paper
• Experimentation in Cognitive Neuroscience and Cognitive Neurobiology 3

  2014cites this paper
• Models and the mosaic of scientific knowledge. The case of immunology.

  2014influential citation
• Model organisms in evo-devo: promises and pitfalls of the comparative approach

  2014cites this paper
• Making Organisms Model Human Behavior: Situated Models in North-American Alcohol Research, since 1950

  2014cites this paper
• Animal Models and the Unity of Neuroscience

  2014cites this paper
• Identifying ontologies in a clinical trial

  2013cites this paper
• The Concept of Evidence in Health Technology Assessment (HTA)

  2013cites this paper
• Mutant mice: experimental organisms as materialised models in biomedicine.

  2013cites this paper
• From humanized mice to human disease: guiding extrapolation from model to target

  2013cites this paper
• EBI Genome Resources

  2013cites this paper
• From agriculture to genomics : the animal side of human genetics and the organization of model organisms in the Longue Durée

  2013cites this paper
• Chance, Experimental Reproducibility, and Mechanistic Regularity

  2013cites this paper
• Stages in the development of a model organism as a platform for mechanistic models in developmental biology: Zebrafish, 1970-2000.

  2012cites this paper
• From humanized mice to human disease: guiding extrapolation from model to target

  2012cites this paper
• Lamarckism and the Constitution of Sociology

  2011cites this paper
• Morphogenesis, Dictyostelium, and the search for shared developmental processes.

  2011cites this paper
• What’s so special about model organisms?

  2011cites this paper
• Business models as models

  2010cites this paper
• Regeneration: Thomas Hunt Morgan’s Window into Development

  2010cites this paper
• Philosophy of Science and Science Studies in the West: An Unrecognized Convergence

  2010cites this paper
• Explanation and Understanding through Scientific Models

  2009cites this paper
• Taking old ideas seriously: Evolution, development, and human behavior

  2008cites this paper
• When is 'race' a race? 1946-2003.

  2008cites this paper
• Instituting Science: Discovery or Construction of Scientific Knowledge?

  2008cites this paper
• How Practical Know‐How Contextualizes Theoretical Knowledge: Exporting Causal Knowledge from Laboratory to Nature

  2008cites this paper
• The Comparative Biology of Human Nature

  2008cites this paper
• The Nature of Nurturant Niches in Ontogeny

  2008cites this paper
• Developmental biologists' choice of subjects approximates to a power law, with no evidence for the existence of a special group of 'model organisms'

  2007cites this paper
• Weed for Thought : Using Arabidopsis thaliana to Understand Plant Biology

  2007cites this paper
• Data without models merging with models without data

  2007cites this paper
• Reliability and Validity of Experiment in the Neurobiology of Learning and Memory

  2007cites this paper
• Growing weed, producing knowledge: an epistemic history of Arabidopsis thaliana.

  2007cites this paper
• The choice of model organisms in evo–devo

  2007cites this paper
• Molecular Biology and its Recent Historiography: A Transnational Quest for the ‘Big Picture’

  2006cites this paper
• On Monetary Incentives

  2005cites this paper
• The Methodology of Experimental Economics: Economic Engineering

  2005cites this paper
• The Methodology of Experimental Economics: From the Laboratory to the Outside World

  2005cites this paper
• The Methodology of Experimental Economics: External Validity

  2005cites this paper
• The Methodology of Experimental Economics: Experiments as Mediators

  2005cites this paper
• The Methodology of Experimental Economics: Causation and Experimental Control

  2005cites this paper
• The Methodology of Experimental Economics: Hypothesis Testing

  2005cites this paper
• The Methodology of Experimental Economics: Analytical Table of Contents

  2005cites this paper
• The Methodology of Experimental Economics: Inside the Laboratory

  2005cites this paper
• Model systems in stem cell biology.

  2004cites this paper
• Experimental Localism and External Validity

  2003cites this paper
• No Real Categories, Only Chimeras and Illusions: The Interplay between Morality and Science in Debates over Embryonic Chimeras

  2003cites this paper
• Bmc Developmental Biology Developmental Biologists' Choice of Subjects Approximates to a Power Law, with No Evidence for the Existence of a Special Group of 'model Organisms'

  year unknowncites this paper
• Scientifi c Fictions as Rules of Inference

  year unknowncites this paper