Methylphenidate regulates activity regulated cytoskeletal associated but not brain-derived neurotrophic factor gene expression in the developing rat striatum.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Neuroscience

• Publication date

  2007-02-09

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.NEUROSCIENCE.2006.10.035PMID 17156936
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A novel method for oral stimulant administration in the neonate rat and similar species.

  2007cited by this paper
• A single cocaine exposure increases BDNF and D3 receptor expression: implications for drug-conditioning

  2005cited by this paper
• Behavioral and Brain Functions

  2005cited by this paper
• Attention-deficit hyperactivity disorder

  2005cited by this paper
• Inhibiting BDNF expression by antisense oligonucleotide infusion causes loss of nigral dopaminergic neurons.

  2005cited by this paper
• Repeated administration of methylphenidate in young, adolescent, and mature rats affects the response to cocaine later in adulthood

  2005cited by this paper
• Molecular reactivity of mesocorticolimbic brain areas of high and low grooming rats after elevated plus maze exposure.

  2005cited by this paper
• Methylphenidate differentially regulates c-fos and fosB expression in the developing rat striatum.

  2005cited by this paper
• BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis.

  2005cited by this paper
• Stimulants: use and abuse in the treatment of attention deficit hyperactivity disorder.

  2005cited by this paper
• Stimulants and the developing brain.

  2005cited by this paper
• Differential expression of arc mRNA and other plasticity-related genes induced by nicotine in adolescent rat forebrain.

  2005cited by this paper
• The control of responsiveness in ADHD by catecholamines: evidence for dopaminergic, noradrenergic and interactive roles.

  2005cited by this paper
• Methylphenidate regulates c-fos and fosB expression in multiple regions of the immature rat brain.

  2005cited by this paper
• Cytoskeletal Genes Regulation by Chronic Morphine Treatment in Rat Striatum

  2004cited by this paper
• Erratum to “The novel monoamine reuptake inhibitor and potential antidepressant, S33005, induces Arc gene expression in cerebral cortex” [Eur. J. Pharmacol. 489 (2004) 179–185]

  2004cited by this paper
• Testing the validity of c-fos expression profiling to aid the therapeutic classification of psychoactive drugs

  2004cited by this paper
• Activity‐regulated cytoskeleton‐associated protein arc is targeted to dendrites and coexpressed with mu‐opioid receptors in postnatal rat caudate‐putamen nucleus

  2004cited by this paper
• The novel monoamine reuptake inhibitor and potential antidepressant, S33005, induces Arc gene expression in cerebral cortex.

  2004cited by this paper
• DeltaFosB: a molecular switch for long-term adaptation in the brain.

  2004cited by this paper
• The Rate of Cocaine Administration Alters Gene Regulation and Behavioral Plasticity: Implications for Addiction

  2004cited by this paper
• Long-term methylphenidate treatment down-regulates c-fos in the striatum of male CD-1 mice

  2004cited by this paper
• Essential role of brain-derived neurotrophic factor in adult hippocampal function.

  2004cited by this paper
• Behavioral reactivity to a noradrenergic challenge after chronic oral methylphenidate (ritalin) in rats.

  2004cited by this paper
• Arc interacts with microtubules/microtubule‐associated protein 2 and attenuates microtubule‐associated protein 2 immunoreactivity in the dendrites

  2004cited by this paper
• Structural plasticity associated with exposure to drugs of abuse.

  2004cited by this paper
• Drug exposure early in life: functional repercussions of changing neuropharmacology during sensitive periods of brain development.

  2004cited by this paper
• Methylphenidate and MK-801, an N-methyl-d-aspartate receptor antagonist: shared biological properties.

  2004cited by this paper
• Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment.

  2004cited by this paper
• Daily methylphenidate administration attenuates c-fos expression in the striatum of prepubertal rats

  2003cited by this paper
• What are the long-term effects of methylphenidate treatment?

  2003cited by this paper
• The activity-regulated cytoskeleton-associated (Arc) gene is a new light-inducible early gene in the mouse suprachiasmatic nucleus.

  2003cited by this paper
• Trk receptors: roles in neuronal signal transduction.

  2003cited by this paper
• Forebrain-specific trkB-receptor knockout mice: behaviorally more hyperactive than "depressive".

  2003cited by this paper
• Antidepressant drug treatment induces Arc gene expression in the rat brain.

  2003cited by this paper
• Amyloid suppresses induction of genes critical for memory consolidation in APP + PS1 transgenic mice

  2003cited by this paper
• Brain-Derived Neurotrophic Factor-Induced Gene Expression Reveals Novel Actions of VGF in Hippocampal Synaptic Plasticity

  2003cited by this paper
• Transcriptional Activation of the Human Brain-derived Neurotrophic Factor Gene Promoter III by Dopamine Signaling in NT2/N Neurons*

  2003cited by this paper
• Differential gene expression in the rat caudate putamen after “binge” cocaine administration: Advantage of triplicate microarray analysis

  2003cited by this paper
• Mapping cortical change across the human life span

  2003cited by this paper
• Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons

  2003cited by this paper
• Toxicokinetic assessment of methylphenidate (Ritalin(R)) in a 13-week oral (gavage) toxicity study in rats using an enantiomeric liquid chromatography/tandem mass spectrometry assay.

  2003cited by this paper
• Identification of differentially regulated transcripts in mouse striatum following methamphetamine treatment – an oligonucleotide microarray approach

  2003cited by this paper
• Differential regulation by stimulants of neocortical expression of mrt1, arc, and homer1a mRNA in the rats treated with repeated methamphetamine

  2003cited by this paper
• Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice.

  2003cited by this paper
• Postnatal development of μ-opioid receptors in the rat caudate-putamen nucleus parallels asymmetric synapse formation

  2003cited by this paper
• Study of pharmacological effects of nilvadipine on RCS rat retinal degeneration by microarray analysis.

  2003cited by this paper
• Attention-deficit hyperactivity disorder and brain-derived neurotrophic factor: a speculative hypothesis.

  2003cited by this paper
• Local synthesis of proteins at synaptic sites on dendrites: role in synaptic plasticity and memory consolidation?

  2002cited by this paper
• Pharmacokinetic and pharmacodynamic properties of stimulants: implications for the design of new treatments for ADHD.

  2002cited by this paper
• Gene Expression Related to Synaptogenesis, Neuritogenesis, and MAP Kinase in Behavioral Sensitization to Psychostimulants

  2002cited by this paper
• Microdialysis monitoring of methylphenidate in blood and brain correlated with changes in dopamine and rat activity.

  2002cited by this paper
• The dopamine D1 receptor is a critical mediator for cocaine‐induced gene expression

  2002cited by this paper
• Brain-Derived Neurotrophic Factor Induces Long-Term Potentiation in Intact Adult Hippocampus: Requirement for ERK Activation Coupled to CREB and Upregulation of Arc Synthesis

  2002cited by this paper
• Monoamine transporter pharmacology and mutant mice.

  2002cited by this paper
• Exposure of Adolescent Rats to Oral Methylphenidate: Preferential Effects on Extracellular Norepinephrine and Absence of Sensitization and Cross-Sensitization to Methamphetamine

  2002cited by this paper
• Pretreatment with methylphenidate sensitizes rats to the reinforcing effects of cocaine.

  2002cited by this paper
• The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes

  2002cited by this paper
• The quantification of gene expression in an animal model of brain ischaemia using TaqMan real-time RT-PCR.

  2002cited by this paper
• Age-related distribution of c-fos expression in the striatum of CD-1 mice after acute methylphenidate administration.

  2002cited by this paper
• Changes in rat frontal cortex gene expression following chronic cocaine.

  2002cited by this paper
• Subchronic methylphenidate administration has no effect on locomotion, emotional behavior, or water maze learning in prepubertal mice.

  2002cited by this paper
• Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration.

  2002cited by this paper
• The ability of amphetamine to evoke arc (Arg 3.1) mRNA expression in the caudate, nucleus accumbens and neocortex is modulated by environmental context.

  2002cited by this paper
• Enhanced Reactivity and Vulnerability to Cocaine Following Methylphenidate Treatment in Adolescent Rats

  2001cited by this paper
• Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation.

  2001cited by this paper
• Effects of chronic and acute methylphenidate hydrochloride (Ritalin) administration on locomotor activity, ultrasonic vocalizations, and neuromotor development in 3- to 11-day-old CD-1 mouse pups.

  2001cited by this paper
• Evaluation of nigrostriatal dopaminergic function in adult +/+ and +/- BDNF mutant mice.

  2001cited by this paper
• Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity.

  2001cited by this paper
• Dopamine regulates brain-derived neurotrophic factor (BDNF) expression in cultured embryonic mouse striatal cells

  2001cited by this paper
• Upregulation of the immediate early gene arc in the brains of rats exposed to environmental enrichment: implications for molecular plasticity.

  2001cited by this paper
• Inhibition of Activity-Dependent Arc Protein Expression in the Rat Hippocampus Impairs the Maintenance of Long-Term Potentiation and the Consolidation of Long-Term Memory

  2000cited by this paper
• Activity-regulated, cytoskeleton-associated protein (Arc) is essential for visceral endoderm organization during early embryogenesis.

  2000cited by this paper
• BDNF regulates eating behavior and locomotor activity in mice

  2000cited by this paper
• deltaFosB: a molecular switch underlying long-term neural plasticity.

  2000cited by this paper
• Effects of Subchronic Methylphenidate Hydrochloride Administration on the Locomotor and Exploratory Behavior of Prepubertal Mice

  2000cited by this paper
• The use of TaqMan RT-PCR assays for semiquantitative analysis of gene expression in CNS tissues and disease models.

  2000cited by this paper
• The Activity‐Regulated Cytoskeletal‐Associated Protein Arc Is Expressed in Different Striosome‐Matrix Patterns Following Exposure to Amphetamine and Cocaine

  2000cited by this paper
• Comparison between intraperitoneal and oral methylphenidate administration: A microdialysis and locomotor activity study.

  2000cited by this paper
• Activation of an Effector Immediate‐early Gene arc by Methampetamine

  2000cited by this paper
• Trends in the prescribing of psychotropic medications to preschoolers.

  2000cited by this paper
• Effects of repeated methylphenidate treatment in the young rat: sensitization of both locomotor activity and stereotyped sniffing.

  1999cited by this paper
• Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity.

  1999cited by this paper
• Dopamine-transporter occupancy after intravenous doses of cocaine and methylphenidate in mice and humans

  1999cited by this paper
• Caffeine‐mediated induction of c‐fos, zif‐268 and arc expression through A1 receptors in the striatum: different interactions with the dopaminergic system

  1999cited by this paper
• Cocaine self-administration in dopamine-transporter knockout mice

  1998cited by this paper
• Cocaine self-administration in dopamine-transporter knockout mice

  1998cited by this paper
• A robust increase in expression of arc gene, an effector immediate early gene, in the rat brain after acute and chronic methamphetamine administration.

  1998cited by this paper
• Effects of Methylphenidate on Extracellular Dopamine, Serotonin, and Norepinephrine: Comparison with Amphetamine

  1997cited by this paper
• Pharmacodynamic Modeling for Change of Locomotor Activity by Methylphenidate in Rats

  1997cited by this paper
• Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

  1996cited by this paper
• Pharmacological Treatment of Psychiatric Disorders in Children and Adolescents

  1996cited by this paper
• Activation of arc, a Putative “Effector” Immediate Early Gene, by Cocaine in Rat Brain

  1995cited by this paper
• Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites.

  1995cited by this paper
• Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system.

  1995cited by this paper
• Everything activates c-fos--how can it matter?

  1993cited by this paper
• BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

  1991cited by this paper
• Dose-dependent kinetics of methylphenidate enantiomers after oral administration of racemic methylphenidate to rats.

  1990cited by this paper
• Pharmacokinetics of methylphenidate in man, rat and monkey.

  1983cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper

• Neuropsychopharmacology: Shaping Neuroplasticity through Arc/Arg3.1 Modulation.

  2024cites this paper
• Effects of Methylphenidate on the Dopamine Transporter and Beyond.

  2022cites this paper
• Effect of pharmacological manipulations on Arc function

  2020cites this paper
• Experience during adolescence shapes brain development: From synapses and networks to normal and pathological behavior.

  2019cites this paper
• Chapter 31 - Psychostimulant-Induced Gene Regulation in Striatal Circuits

  2017cites this paper
• Methylphenidate disrupts cytoskeletal homeostasis and reduces membrane-associated lipid content in juvenile rat hippocampus

  2017cites this paper
• Chronic methylphenidate regulates genes and proteins mediating neuroplasticity in the juvenile rat brain.

  2017cites this paper
• Molecular and Neurochemical Effects of Methylphenidate on the Developing Brain

  2017cites this paper
• Quand le cerveau succombe aux addictions: Facteurs de vulnérabilité, implication des circuits cortico-striataux et développement d’une technique de neuromodulation pour favoriser le sevrage

  2016influential citation
• The Impact of Chronic Early Administration of Psychostimulants on Brain Expression of BDNF and Other Neuroplasticity-Relevant Proteins

  2015cites this paper
• Acute oral administration of low doses of methylphenidate targets calretinin neurons in the rat septal area

  2015cites this paper
• Neurobiology of ADHD From Childhood to Adulthood

  2015cites this paper
• Effect of Chronic DL-Amphetamine Exposure on Brain Volume, Anxiogenic, Locomotor, and Social Behaviors in Male SD Rats

  2014cites this paper
• Selective serotonin re‐uptake inhibitors potentiate gene blunting induced by repeated methylphenidate treatment: Zif268 versus Homer1a

  2014cites this paper
• Life-long consequences of juvenile exposure to psychotropic drugs on brain and behavior.

  2014cites this paper
• Prefrontal cortical and striatal transcriptional responses to the reinforcing effect of repeated methylphenidate treatment in the spontaneously hypertensive rat, animal model of attention-deficit/hyperactivity disorder (ADHD)

  2014cites this paper
• Molecular genetic studies of ADHD and its candidate genes: a review.

  2014cites this paper
• Juvenile methylphenidate reduces prefrontal cortex plasticity via D3 receptor and BDNF in adulthood

  2014cites this paper
• There is consensus that changes in gene regulation are critical for psychostimulant addiction and other long-lasting behavioral pathologies ( Renthal

  2014cites this paper
• The Role of Dopamine D1 and D2 Receptors in Adolescent Methylphenidate Conditioned Place Preference: Sex Differences and Brain-Derived Neurotrophic Factor

  2014cites this paper
• Analysis of the role of D 2 receptors in methylphenidate-induced conditioned place preference

  2014cites this paper
• Changes in plasma Brain-derived neurotrophic factor (BDNF) levels induced by methylphenidate in children with Attention deficit-hyperactivity disorder (ADHD).

  2013cites this paper
• Methylphenidate Treatment Leads to Abnormalities on Krebs Cycle Enzymes in the Brain of Young and Adult Rats

  2013cites this paper
• Addiction-related gene regulation: risks of exposure to cognitive enhancers vs. other psychostimulants.

  2013influential citation
• Altered gene expression in the prefrontal cortex of young rats induced by the ADHD drug atomoxetine.

  2013cites this paper
• Sex and dose-related differences in methylphenidate adolescent locomotor sensitization and effects on brain-derived neurotrophic factor

  2012cites this paper
• Hydrophilic interaction chromatography in drug analysis

  2012cites this paper
• A review of psychostimulant-induced neuroadaptation in developing animals

  2011cites this paper
• Expression of activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) in the nucleus accumbens is critical for the acquisition, expression and reinstatement of morphine-induced conditioned place preference.

  2011cites this paper
• Neuroadaptations Involved in Long-Term Exposure to ADHD Pharmacotherapies: Alterations That Support Dependence Liability of These Medications

  2011cites this paper
• Epigenetics in Developmental Disorder: ADHD and Endophenotypes.

  2011cites this paper
• xpression of activity-regulated cytoskeleton-associated protein ( Arc / Arg 3 . 1 ) in he nucleus accumbens is critical for the acquisition , expression and einstatement of morphine-induced conditioned place preference

  2011cites this paper
• Sub-chronic exposure to atomoxetine up-regulates BDNF expression and signalling in the brain of adolescent spontaneously hypertensive rats: comparison with methylphenidate.

  2010cites this paper
• Inhibition of Mitochondrial Respiratory Chain in the Brain of Adult Rats After Acute and Chronic Administration of Methylphenidate

  2010cites this paper
• Methylphenidate affects memory, brain-derived neurotrophic factor immunocontent and brain acetylcholinesterase activity in the rat.

  2010cites this paper
• Postnatal brain development and psychotropic drugs. Effects on animals and animal models of depression and attention-deficit/hyperactivity disorder.

  2010cites this paper
• Chronic low dose Adderall XR down-regulates cfos expression in infantile and prepubertal rat striatum and cortex.

  2010cites this paper
• Psychostimulant-Induced Gene Regulation in Corticostriatal Circuits

  2010cites this paper
• Meta‐analysis of brain‐derived neurotrophic factor p.Val66Met in adult ADHD in four European populations

  2010cites this paper
• Metilfenidato causa alterações neuroquímicas e comportamentais em ratos

  2010cites this paper
• Handbook of basal ganglia structure and function

  2010cites this paper
• Juvenile Methylphenidate Exposure and Factors That Influence Incentive Processing

  2009cites this paper
• Differential regulation of psychostimulant‐induced gene expression of brain derived neurotrophic factor and the immediate‐early gene Arc in the juvenile and adult brain

  2009cites this paper
• The Arc of synaptic memory

  2009cites this paper
• Methylphenidate treatment increases Na+, K+-ATPase activity in the cerebrum of young and adult rats

  2009cites this paper
• Fluorescent Arc/Arg3.1 indicator mice: a versatile tool to study brain activity changes in vitro and in vivo.

  2009cites this paper
• A Biological/Genetic Perspective: The Addicted Brain

  2009cites this paper
• Neurotrophic factors and structural plasticity in addiction.

  2009cites this paper
• Association study of 10 genes encoding neurotrophic factors and their receptors in adult and child attention-deficit/hyperactivity disorder.

  2008cites this paper
• Methylphenidate increases creatine kinase activity in the brain of young and adult rats.

  2008influential citation
• Upregulation of Arc mRNA expression in the prefrontal cortex following cue‐induced reinstatement of extinguished cocaine‐seeking behavior

  2008cites this paper
• The advantages of ESI-MS detection in conjunction with HILIC mode separations: Fundamentals and applications.

  2008cites this paper
• Methylphenidate and cocaine: the same effects on gene regulation?

  2007cites this paper