Protective effects of the flavonoid mixture, silymarin, on fetal rat brain and liver.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Ethnopharmacology

• Publication date

  1999-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0378-8741(98)00144-5PMID 10350368
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Comparative bioavailability of Silipide, a new flavanolignan complex, in rats

  2010cited by this paper
• Milk Thistle (Silybum marianum) for the Therapy of Liver Disease

  1998cited by this paper
• Hepatoprotective properties of Silybum marianum herbal preparation on ethanol-induced liver damage

  1996cited by this paper
• Scavenging effect of silipide, a new silybin-phospholipid complex, on ethanol-derived free radicals.

  1995cited by this paper
• Effect of acute ethanol exposure on cultured fetal rat hepatocytes: relation to mitochondrial function.

  1994cited by this paper
• Effects of in utero administration of alcohol on glutathione levels in brain and liver.

  1993cited by this paper
• A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB1016) in chronic active hepatitis.

  1993cited by this paper
• Effect of ethanol on rat fetal hepatocytes: Studies on cell replication, lipid peroxidation and glutathione

  1993cited by this paper
• Protective activity of silipide on liver damage in rodents.

  1992cited by this paper
• Liquid Chromatographic Assay of Silybin in Human Plasma and Urine

  1991cited by this paper
• Preliminary Clinical Development of Silipide: A New Complex of Silybin in Toxic Liver Disorders

  1991cited by this paper
• Silybin Dihemisuccinate Protects Against Glutathione Depletion and Lipid Peroxidation Induced by Acetaminophen on Rat Liver

  1989cited by this paper
• Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver.

  1989cited by this paper
• Stimulatory effect of Silibinin on the DNA synthesis in partially hepatectomized rat livers: non-response in hepatoma and other malign cell lines.

  1986cited by this paper
• Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat.

  1985cited by this paper
• [Mechanism of action of silibinin. V. Effect of silibinin on the synthesis of ribosomal RNA, mRNA and tRNA in rat liver in vivo].

  1984cited by this paper
• Untersuchungen zum Wirkungsmechanismus von Silibinin, V. Einfluß von Silibinin auf die Synthese ribosomaler RNA, mRNA und tRNA in Rattenlebern in vivo

  1984cited by this paper
• Effect of silymarin on chemical, functional, and morphological alterations of the liver. A double-blind controlled study.

  1982cited by this paper
• Stimulierung der RNA-Synthese in Rattenleber und in isolierten Hepatozyten durch Silybin, einen antihepatotoxischen Wirkstoff ausSilybum marianumL. Gaertn.

  1976cited by this paper
• [Stimulation of RNA synthesis in rat liver and isolated hepatocytes by silybin, an antihepatotoxic agent from Silybum marianum L. Gaertn (author's transl)].

  1976cited by this paper

• A comprehensive review on phytosomes as an emerging technology for delivering herbal medicines.

  2025cites this paper
• Vesicle delivery systems of functional substances for precision nutrition.

  2024cites this paper
• Phytosome: An Emerging Technique for Improving Herbal Drug Delivery

  2023cites this paper
• Curative role of silymarin against reproductive toxicity of the female system during the critical periods of life

  2023cites this paper
• Comparison Between Hesperidin, Coumarin, and Deferoxamine Iron Chelation and Antioxidant Activity Against Excessive Iron in the Iron Overloaded Mice

  2022cites this paper
• Silybins are stereospecific regulators of the 20S proteasome.

  2022cites this paper
• Phytosomes as Innovative Delivery Systems for Phytochemicals: A Comprehensive Review of Literature

  2021cites this paper
• Silymarin protects the structure of kidney in the neonatal rats exposed to maternal cadmium toxicity: A stereological study

  2020cites this paper
• DEVELOPMENT AND CHARACTERIZATION OF HERBOSOMES COMPLEX

  2020influential citation
• Trehalose conjugates of silybin as prodrugs for targeting toxic Aβ aggregates.

  2020cites this paper
• Novel Drug Delivery Systems for Phytoconstituents

  2019cites this paper
• Ethanol Exposure During Development, and Brain Oxidative Stress

  2019cites this paper
• Silymarin as Herbal Medicine- A Review

  2018cites this paper
• Phytosome as a Prominent Option in Drug Delivery for the Treatment of the Diseases: A Review

  2018cites this paper
• PHYTOSOMES-NOVEL DRUG DELIVERY SYSTEM

  2017cites this paper
• Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry.

  2017cites this paper
• The Impact of Silymarin on Improvement of Hepatic Abnormalities in Patients with Severe Preeclampsia: A Randomized Clinical Trial

  2017cites this paper
• Impact of nanotechnology on global trade of herbal drugs: An overview

  2017cites this paper
• A REVIEW ON PHYTOSOMES: NOVEL APPROACH FOR HERBAL PHYTOCHEMICALS

  2017cites this paper
• Lead Toxicity and Flavonoids

  2017cites this paper
• Prenatal alcohol exposure and offspring liver dysfunction: a systematic review and meta-analysis

  2016cites this paper
• TO STUDY THE EFFECT OF SILYMARIN AGAINST LIPOPOLYSACHHARIDES INDUCED NEUROINFLAMMATION IN MICE

  2016cites this paper
• PHYTOSOMES: FROM HERBAL DRUG DELIVERY TO TARGETED CLINICAL THERAPY

  2016cites this paper
• The impact of Silymarin on improvement of platelet abnormalities in patients with severe preeclampsia

  2016cites this paper
• Liposomal and Phytosomal Formulations

  2016cites this paper
• PHYTOSOMES: A BRIEF OVERVIEW

  2016cites this paper
• Phytosome as a Novel Biomedicine: A Microencapsulated Drug DeliverySystem

  2015cites this paper
• Take Research to New Heights PHYTOSOMES : A NOVEL DRUG DELIVERY SYSTEM

  2015cites this paper
• Protective Effects of Silibinin and Its Possible Mechanism of Action in Mice Exposed to Chronic Unpredictable Mild Stress

  2015cites this paper
• Neurotrophic and antioxidant effects of silymarin comparable to 4-methylcatechol in protection against gentamicin-induced ototoxicity in guinea pigs

  2015cites this paper
• HERBOSOMES: A POTENTIAL CARRIERS FOR THE BIOAVAILABILITY ENHANCEMENT OF HERBAL EXTRACTS

  2015cites this paper
• Effect of Endurance Swimming Training and Silymarin Treatment on Changes in Liver Apoptotic Index in Pregnant Rats Exposed to Cadmium

  2015cites this paper
• Phytosomes: A Noval Drug Delivery System for Phytoconstituents

  2014cites this paper
• Protection of the Developing Brain with Anthocyanins Against Ethanol-Induced Oxidative Stress and Neurodegeneration

  2014cites this paper
• Oxidative Stress in Fetal Alcohol Spectrum Disorders – Insights for the Development of Antioxidant-Based Therapies

  2014cites this paper
• Enhancement of Hepatoprotective Effect of Herbal Formulation (F1) on Carbon tetrachloride and Ethanol Induced Liver Toxicity in Albino Rats

  2014cites this paper
• Silymarin effect on amyloid-β plaque accumulation and gene expression of APP in an Alzheimer’s disease rat model

  2014cites this paper
• A general introduction to medicinal plants and silybum marianum

  2014cites this paper
• PHYTOSOMES: A NOVEL DRUG DELIVERY SYSTEM

  2014cites this paper
• PHYTOSOME: RECENT ADVANCE RESEARCH FOR NOVEL DRUG DELIVERY SYSTEM

  2014cites this paper
• Phytosomes- A Review

  2014cites this paper
• A REVIEW ON PHYTOSOMES, THEIR CHARACTERIZATION, ADVANCEMENT & POTENTIAL FOR TRANSDERMAL APPLICATION

  2013cites this paper
• Anthocyanins Protect Against Ethanol-Induced Neuronal Apoptosis via GABAB1 Receptors Intracellular Signaling in Prenatal Rat Hippocampal Neurons

  2013cites this paper
• Omega-3 supplementation can restore glutathione levels and prevent oxidative damage caused by prenatal ethanol exposure.

  2013cites this paper
• Phytosome: Phytolipid Drug Dilivery System for Improving Bioavailability of Herbal Drug

  2013cites this paper
• Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol

  2013cites this paper
• Hepatoprotective effect of poly herbal formulation against various hepatotoxic agents in rats

  2012cites this paper
• PHYTOSOME: A NOVEL REVOLUTION IN HERBAL DRUGS

  2012cites this paper
• Silymarin protects neurons from oxidative stress associated damages in focal cerebral ischemia: a behavioral, biochemical and immunohistological study in Wistar rats.

  2011cites this paper
• Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment.

  2011cites this paper
• Using biochemical findings to study the effect of silymarin on the liver of pregnant rat that consumed ethanol.

  2011cites this paper
• The role of oxidative stress in fetal alcohol spectrum disorders.

  2011cites this paper
• PHYTOSOME- A NOVEL APPROACH FOR HERBAL DRUG DELIVERY

  2011cites this paper
• PHYTOSOMES: NOVEL APPROACH FOR DELIVERING HERBAL EXTRACT WITH IMPROVED BIOAVAILABILITY

  2011cites this paper
• Effects of Silibinin on Hair Follicle Stem Cells Differentiation to Neural-like Cells

  2011cites this paper
• The preventive effect of oral EGCG in a fetal alcohol spectrum disorder mouse model.

  2010cites this paper
• Le rôle des acides gras polyinsaturés dans la prévention des effets de l'exposition prénatale à l'alcool sur le développement des nouveau-nés inuits : une étude épidémiologique

  2010cites this paper
• PHYTOSOMES: A NOVEL DOSAGE FORM FOR ENHANCEMENT OF BIOAVAILABILITY OF BOTANICALS AND NEUTRACEUTICALS

  2010cites this paper
• Maternal treatment of rats with the new pyridoindole antioxidant during pregnacy and lactation resulting in improved offspring hippocampal resistance to ischemia in vitro.

  2010cites this paper
• A REVIEW ON GENESIS AND CHARACTERIZATION OF PHYTOSOMES

  2010cites this paper
• Supramolecular phospholipids-polyphenolics interactions: the PHYTOSOME strategy to improve the bioavailability of phytochemicals.

  2010cites this paper
• Study the Effects of Oral Administration of Silymarin in Preventing Consequences of Ethanol on Liver during Pregnancy

  2010cites this paper
• PHYTOSOME: A NOVEL DRUG DELIVERY SYSTEM FOR HERBAL MEDICINE

  2010cites this paper
• Silibinin Attenuates Amyloid β25–35 Peptide-Induced Memory Impairments: Implication of Inducible Nitric-Oxide Synthase and Tumor Necrosis Factor-α in Mice

  2009cites this paper
• Ochnaflavone, a Natural Biflavonoid, Induces Cell Cycle Arrest and Apoptosis in HCT-15 Human Colon Cancer Cells

  2009cites this paper
• Silibinin prevents amyloid β peptide‐induced memory impairment and oxidative stress in mice

  2009cites this paper
• RESEARCH PAPER Silibinin prevents amyloid b peptide-induced memory impairment and oxidative stress in mice

  2009cites this paper
• Anti‐ and pro‐mutagenic effects of silymarin in the ames bacterial reverse mutation assay

  2009cites this paper
• Silibinin Attenuates Amyloid (cid:1) 25–35 Peptide-Induced Memory Impairments: Implication of Inducible Nitric-Oxide Synthase and Tumor Necrosis Factor- (cid:2) in Mice

  2009cites this paper
• Anthocyanins: Are They Beneficial in Treating Ethanol Neurotoxicity?

  2009cites this paper
• Phytosomes: the Emerging Technology for Enhancement of Bioavailability of Botanicals and Nutraceuticals

  2008cites this paper
• Silybin and silymarin--new and emerging applications in medicine.

  2007cites this paper
• Novel molecular targets for the prevention of fetal alcohol syndrome.

  2007cites this paper
• Protective effect of silymarin on oxidative stress in rat brain.

  2007cites this paper
• Anticancer potential of silymarin: from bench to bed side.

  2006cites this paper
• The effects of yarrow (Achillea millefolium) and herbal supplements on growth performance and nutrient utilisation of broiler chickens

  2005cites this paper
• Silybin and silymarin--new effects and applications.

  2005cites this paper
• A new silymarin preparation based on solid dispersion technique

  2005cites this paper
• EFFECT OF TETRAHYDROCURCUMIN ON ERYTHROMYCIN ESTOLATE-INDUCED LIPID PEROXIDATION IN RATS

  2005cites this paper
• Protective role of tetrahydrocurcumin against erythromycin estolate-induced hepatotoxicity.

  2004cites this paper
• Protective effect of α‐lipoic acid against chloroquine‐induced hepatotoxicity in rats

  2004cites this paper
• Normalizing Effects of Bioflavonoids on EtOH-induced Indices of Lipid Peroxidation in Rat Neonates and Dams

  2003cites this paper
• The Many Faces of Silybum marianum (Milk Thistle): Part 2 - Clinical Uses, Safety, and Types of Preparations

  2003cites this paper
• Antioxidants and fetal protection against ethanol teratogenicity. I. Review of the experimental data and implications to humans.

  2003cites this paper
• Hepatoprotective Activity of Moringa oleifera on Antitubercular Drug-Induced Liver Damage in Rats

  2002cites this paper
• Bmc Complementary and Alternative Medicine Impact of in Utero Exposure to Etoh on Corpus Callosum Development and Paw Preference in Rats: Protective Effects of Silymarin

  2002cites this paper
• MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide.

  2002cites this paper
• Dietary Flavonoids as Potential Neuroprotectants

  2002cites this paper
• The Use of a Silymarin/Phospholipid Compound as a Fetoprotectant from Ethanol-Induced Behavioral Deficits

  2002cites this paper
• Treatment of Hepatitis C with Milk Thistle?

  2001cites this paper
• Fetoprotectivity of the flavanolignan compound siliphos against ethanol‐induced toxicity

  2000cites this paper
• A REVIEW ON PHYTOSOME

  year unknowncites this paper