Identification and expression analysis of a novel transcript of the human PRMT2 gene resulted from alternative polyadenylation in breast cancer.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Gene

• Publication date

  2011-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.gene.2011.06.022PMID 21820040
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2.

  2010cited by this paper
• Disruption of Protein Arginine N-Methyltransferase 2 Regulates Leptin Signaling and Produces Leanness In Vivo Through Loss of STAT3 Methylation

  2010cited by this paper
• Identification and Characterization of Two Novel Isoforms of Pirh2 Ubiquitin Ligase That Negatively Regulate p53 Independent of RING Finger Domains*

  2009cited by this paper
• Human protein arginine methyltransferases in vivo – distinct properties of eight canonical members of the PRMT family

  2009influential reference
• Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4.

  2009cited by this paper
• Utilization of an intron located polyadenlyation site resulted in four novel glutamate decarboxylase transcripts

  2009cited by this paper
• Beta-catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2

  2009cited by this paper
• Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors

  2008cited by this paper
• Protein Arginine Methyltransferase 5 Suppresses the Transcription of the RB Family of Tumor Suppressors in Leukemia and Lymphoma Cells

  2008cited by this paper
• Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential.

  2007cited by this paper
• Alternative Splicing Yields Protein Arginine Methyltransferase 1 Isoforms with Distinct Activity, Substrate Specificity, and Subcellular Localization*

  2007cited by this paper
• Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses.

  2007cited by this paper
• Arginine methylation at a glance

  2007influential reference
• PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor.

  2007influential reference
• Histone arginine methylation regulates pluripotency in the early mouse embryo

  2007cited by this paper
• Characterization of prmt7alpha and beta isozymes from Chinese hamster cells sensitive and resistant to topoisomerase II inhibitors.

  2006cited by this paper
• Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases.

  2006cited by this paper
• Protein methyltransferase 2 inhibits NF-kappaB function and promotes apoptosis.

  2006cited by this paper
• Characterization of prmt7α and β isozymes from Chinese hamster cells sensitive and resistant to topoisomerase II inhibitors

  2006cited by this paper
• FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues.

  2006cited by this paper
• Protein Methyltransferase 2 Inhibits NF-κB Function and Promotes Apoptosis

  2006cited by this paper
• Coactivator-associated Arginine Methyltransferase 1, CARM1, Affects Pre-mRNA Splicing in an Isoform-specific Manner*♦

  2005cited by this paper
• Function of alternative splicing.

  2005cited by this paper
• Arginine methylation signals mRNA export

  2004cited by this paper
• Function of Alternative Splicing

  2004cited by this paper
• Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

  2002cited by this paper
• The Coactivator-associated Arginine Methyltransferase Is Necessary for Muscle Differentiation

  2002cited by this paper
• Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs

  2002cited by this paper
• A genomic view of alternative splicing

  2002cited by this paper
• Lipopolysaccharide-induced Methylation of HuR, an mRNA-stabilizing Protein, by CARM1*

  2002cited by this paper
• Identification of Protein Arginine Methyltransferase 2 as a Coactivator for Estrogen Receptor α*

  2002cited by this paper
• The Novel Human Protein Arginine N-Methyltransferase PRMT6 Is a Nuclear Enzyme Displaying Unique Substrate Specificity*

  2002cited by this paper
• Multiple transcription initiation sites, alternative splicing, and differential polyadenylation contribute to the complexity of human neurofibromatosis 2 transcripts.

  2002cited by this paper
• State of the arg: protein methylation at arginine comes of age.

  2001cited by this paper
• PRMT5, Which Forms Distinct Homo-oligomers, Is a Member of the Protein-arginine Methyltransferase Family*

  2001cited by this paper
• Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2).

  1998influential reference
• PRMT 3, a Type I Protein Arginine N-Methyltransferase That Differs from PRMT1 in Its Oligomerization, Subcellular Localization, Substrate Specificity, and Regulation*

  1998cited by this paper
• Identification and mapping of a novel human gene, HRMT1L1, homologous to the rat protein arginine N-methyltransferase 1 (PRMT1) gene

  1997influential reference
• Alternative poly(A) site selection in complex transcription units: means to an end?

  1997cited by this paper
• The Mammalian Immediate-early TIS21 Protein and the Leukemia-associated BTG1 Protein Interact with a Protein-arginine N-Methyltransferase*

  1996cited by this paper

• The role of alternative polyadenylation in breast cancer

  2024cites this paper
• Exploring the role of estrogen and progestins in breast cancer: A genomic approach to diagnosis.

  2024cites this paper
• Citrullination and the protein code: crosstalk between post-translational modifications in cancer

  2023cites this paper
• Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1

  2023cites this paper
• Advances in Research on Protein Arginine Methyltransferase 2: Functions and Diseases.

  2023cites this paper
• Alternative polyadenylation: An enigma of transcript length variation in health and disease

  2021cites this paper
• Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase

  2021cites this paper
• Emerging patterns and implications of breast cancer epigenetics

  2021cites this paper
• Arginine methylation in the epithelial‐to‐mesenchymal transition

  2021cites this paper
• Epigenetic Regulator Enzymes and Their Implications in Distinct Malignancies

  2020cites this paper
• Emerging Roles of RNA 3′-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders

  2020cites this paper
• PRMT2β suppresses autophagy and glycolysis pathway in human breast cancer MCF-7 cell lines.

  2019cites this paper
• Epigenetic arginine methylation in breast cancer: emerging therapeutic strategies.

  2019cites this paper
• Regulation of histone arginine methylation/demethylation by methylase and demethylase

  2019cites this paper
• Diagnostic biomarker SDMA for kidney disease in dogs and cats.

  2018cites this paper
• Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations.

  2018cites this paper
• Protein Arginine Methyltransferase 2 Inhibits Angiotensin II-Induced Proliferation and Inflammation in Vascular Smooth Muscle Cells

  2018cites this paper
• Gene and Cell Therapy: Biology and Applications

  2018cites this paper
• SETting up Methylation in Mammalian Cells: Role of Histone Methyltransferases in Disease and Development

  2018cites this paper
• The Landscape of Histone Modification in Cancer Metastasis

  2018influential citation
• PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X

  2017cites this paper
• PRMT2β, a C-terminal splice variant of PRMT2, inhibits the growth of breast cancer cells.

  2017cites this paper
• Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors

  2017cites this paper
• PRMT 2 β , a C-terminal splice variant of PRMT 2 , inhibits the growth of breast cancer cells

  2017cites this paper
• Small Molecule Inhibitors of Protein Arginine Methyltransferases

  2016cites this paper
• The Functions of Histone Modification Enzymes in Cancer.

  2016cites this paper
• Characterization of arginine methyltransferase PRMT8 in cells with increased plasticity

  2016cites this paper
• Therapeutic Implications of Epigenetic Signaling in Breast Cancer

  2016cites this paper
• Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation

  2015cites this paper
• Investigating the Role of Protein Arginine Methyltransferases in Breast Cancer Etiology

  2015cites this paper
• Arginine methyltransferases as novel therapeutic targets for breast cancer.

  2015influential citation
• Identification of the PRMT1v1 and PRMT1v2 specific interactomes by quantitative mass spectrometry in breast cancer cells

  2015cites this paper
• Role of PRMTs in cancer: Could minor isoforms be leaving a mark?

  2014cites this paper
• Nuclear loss of protein arginine N-methyltransferase 2 in breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein

  2014cites this paper
• Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression

  2014cites this paper
• Role of PRMTs in cancer: Could minor isoforms be leaving a mark? World Journal of Biological Chemistry

  2014cites this paper
• Identification of splice variants, expression analysis and single nucleotide polymorphisms of the PRMT2 gene in dairy cattle.

  2014cites this paper
• Identification and characterization of novel spliced variants of PRMT2 in breast carcinoma

  2012cites this paper
• Genome-wide alternative polyadenylation in animals: insights from high-throughput technologies.

  2012cites this paper
• Protein arginine methyltransferases and cancer

  2012cites this paper