Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Arthritis & Rheumatology

• Publication date

  2017-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/art.40101PMID 28320059PMCID PMC5489381
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Running and Knee Osteoarthritis: A Systematic Review and Meta-analysis

  2017cited by this paper
• Prior voluntary wheel running attenuates neuropathic pain

  2016cited by this paper
• Exercise prevents development of autonomic dysregulation and hyperalgesia in a mouse model of chronic muscle pain

  2016cited by this paper
• Central Sensitization and Neuropathic Features of Ongoing Pain in a Rat Model of Advanced Osteoarthritis.

  2016cited by this paper
• Association between subchondral bone structure and osteoarthritis histopathological grade

  2016cited by this paper
• Regular physical activity prevents chronic pain by altering resident muscle macrophage phenotype and increasing interleukin-10 in mice

  2016cited by this paper
• An update on the pathophysiology of osteoarthritis.

  2016cited by this paper
• Emerging Relationships between Exercise, Sensory Nerves, and Neuropathic Pain

  2016cited by this paper
• Endogenous Opioid Activity in the Anterior Cingulate Cortex Is Required for Relief of Pain

  2015cited by this paper
• Exercise therapy normalizes BDNF upregulation and glial hyperactivity in a mouse model of neuropathic pain

  2015cited by this paper
• Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7

  2015cited by this paper
• Osteoarthritis pain: nociceptive or neuropathic?

  2014cited by this paper
• Variations Among Primary Care Physicians in Exercise Advice, Imaging, and Analgesics for Musculoskeletal Pain: Results From a Factorial Experiment

  2014cited by this paper
• Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: A potential biomarker of efficacy

  2014cited by this paper
• Descending pain modulation and chronification of pain

  2014cited by this paper
• OARSI guidelines for the non-surgical management of knee osteoarthritis.

  2014cited by this paper
• Effect of interval-training exercise on subchondral bone in a chemically-induced osteoarthritis model.

  2014cited by this paper
• The relationship between knee pain characteristics and symptom state acceptability in people with knee osteoarthritis.

  2014cited by this paper
• Epidemiology of osteoarthritis.

  2013cited by this paper
• Physical Exercise Induces Excess Hsp72 Expression and Delays the Development of Hyperalgesia and Allodynia in Painful Diabetic Neuropathy Rats

  2013cited by this paper
• Microglia and intractable chronic pain

  2013cited by this paper
• Mechanisms of Chronic Pain in Osteoarthritis

  2012cited by this paper
• Afferent drive elicits ongoing pain in a model of advanced osteoarthritis

  2012cited by this paper
• Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis.

  2012cited by this paper
• Characterisation of a Peripheral Neuropathic Component of the Rat Monoiodoacetate Model of Osteoarthritis

  2012cited by this paper
• Aging and Osteoarthritis: An Inevitable Encounter?

  2012cited by this paper
• The changing demographics of total joint arthroplasty recipients in the United States and Ontario from 2001 to 2007.

  2012cited by this paper
• Aerobic Activity in Prevention and Symptom Control of Osteoarthritis

  2012cited by this paper
• Exercise-induced pain requires NMDA receptor activation in the medullary raphe nuclei.

  2012cited by this paper
• Ongoing pain in the MIA model of osteoarthritis.

  2011cited by this paper
• The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats

  2011cited by this paper
• Regular Exercise Reverses Sensory Hypersensitivity in a Rat Neuropathic Pain Model: Role of Endogenous Opioids

  2011influential reference
• The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain

  2011cited by this paper
• OARSI-FDA initiative: defining the disease state of osteoarthritis.

  2011cited by this paper
• Osteoarthritis: an update with relevance for clinical practice

  2011cited by this paper
• Forced‐exercise delays neuropathic pain in experimental diabetes: effects on voltage‐activated calcium channels

  2011cited by this paper
• Sensitization in patients with painful knee osteoarthritis

  2010cited by this paper
• Epidemiology of osteoarthritis.

  2010cited by this paper
• Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice

  2009cited by this paper
• Modulation of transient receptor potential vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C

  2009cited by this paper
• The symptoms of osteoarthritis and the genesis of pain.

  2009cited by this paper
• Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain

  2009cited by this paper
• The symptoms of osteoarthritis and the genesis of pain.

  2008cited by this paper
• Joint capsule treatment with enkephalin‐encoding HSV‐1 recombinant vector reduces inflammatory damage and behavioural sequelae in rat CFA monoarthritis

  2008cited by this paper
• Understanding the pain experience in hip and knee osteoarthritis--an OARSI/OMERACT initiative.

  2008cited by this paper
• Synovitis detected on magnetic resonance imaging and its relation to pain and cartilage loss in knee osteoarthritis

  2007cited by this paper
• Extended swimming exercise reduces inflammatory and peripheral neuropathic pain in rodents.

  2007cited by this paper
• Prevalence of knee osteoarthritis in the United States: arthritis data from the Third National Health and Nutrition Examination Survey 1991-94.

  2006cited by this paper
• Development and pharmacological characterization of a rat model of osteoarthritis pain

  2005cited by this paper
• Low-intensity exercise reverses chronic muscle pain in the rat in a naloxone-dependent manner.

  2005cited by this paper
• Dose-response relationship for exercise on severity of experimental osteoarthritis in rats: a pilot study.

  2004cited by this paper
• In vivo micro computed tomography of subchondral bone in the rat after intra-articular administration of monosodium iodoacetate.

  2004cited by this paper
• The Nature of the Arrestin·Receptor Complex Determines the Ultimate Fate of the Internalized Receptor*

  2003cited by this paper
• Sensitivity to the effects of opioids in rats with free access to exercise wheels: µ-opioid tolerance and physical dependence

  2003cited by this paper
• Serum opioid activity after physical exercise in rats.

  1999cited by this paper
• Quantitative assessment of tactile allodynia in the rat paw.

  1994cited by this paper
• Effects of exercise training on brain opioid peptides and serum LH in female rats.

  1984cited by this paper
• The rat brain in stereotaxic coordinates: Authors: George Paxinos & Charles Watson Academic Press Australia, 1982 Softback, 154 pages (including 71 plates), 35.00 Aust $

  1983influential reference
• The Effect of Running on Plasma β-Endorphin

  1982cited by this paper
• The effect of running on plasma beta-endorphin.

  1981cited by this paper
• The effect of running on plasma beta-endorphin.

  1981cited by this paper
• AChE-stained horizontal sections of the rat brain in stereotaxic coordinates.

  1980cited by this paper

• Pathological Degeneration of Disc and Bone Is Associated With Chronic Low Back Pain in a Rat Model With Intradiscal Monosodium Iodoacetate

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• ​Treadmill running modulates infrapatellar fat pad remodeling in osteoarthritic rats in an intensity-dependent manner.

  2026cites this paper
• JP4-039 protects chondrocytes from ferroptosis to attenuate osteoarthritis progression by promoting Pink1/Parkin-dependent mitophagy

  2025cites this paper
• Blockade of opioid receptors prevents the effect of exercise on neuropathic pain in mice, promoting immunoregulation in the brainstem and prefrontal cortex.

  2025cites this paper
• Exercise as Osteoarthritis Treatment in Wistar Rats Promotes Frequency-Dependent Benefits

  2025influential citation
• The Comparative Study of Clinical Efficacy of Different Load-bearing Exercise Therapies for Early Knee Osteoarthritis Patients

  2025cites this paper
• Low-intensity muscle contraction exercise reduces pain sensitivity by modulating peripheral pathology and spinal sensitization in end-stage knee osteoarthritis rats

  2025cites this paper
• Effects of resistance exercise on the inflammatory profile of the tibiofemoral joint in a rheumatoid arthritis model.

  2025cites this paper
• Physical exercise ameliorates pain, mood alterations and neuroinflammation in a murine model of osteoarthritis.

  2025cites this paper
• Voluntary running improves synaptic degeneration of the anterior cingulate cortex in knee osteoarthritis

  2025cites this paper
• Age- and Sex-Dependent Effects of Moderate Exercise on Endogenous Pain Inhibition in Rats

  2024cites this paper
• Effects of platelet-rich plasma combined with isometric quadriceps contraction on cartilage in a rat model of knee osteoarthritis

  2024cites this paper
• Mild Exercise Expedites Joint Clearance and Slows Joint Degradation in a Joint Instability Model of Osteoarthritis in Male Rats.

  2024cites this paper
• Revisiting prostaglandin E2: A promising therapeutic target for osteoarthritis.

  2024cites this paper
• Pathological Characteristics of Monosodium Iodoacetate-Induced Osteoarthritis in Rats

  2023cites this paper
• Face and Predictive Validity of MI-RAT (Montreal Induction of Rat Arthritis Testing), a Surgical Model of Osteoarthritis Pain in Rodents Combined with Calibrated Exercise

  2023cites this paper
• Effect of Moderate Exercise on the Superficial Zone of Articular Cartilage in Age-Related Osteoarthritis

  2023cites this paper
• Animal Models of Osteoarthritis: Updated Models and Outcome Measures 2016–2023

  2023cites this paper
• Mechanism and pharmacotherapy of osteoarthritis – recent advances in the endocannabinoid system targeting”

  2023influential citation
• Wheel Running Exacerbates Joint Damage after Meniscal Injury in Mice, but Does Not Alter Gait or Physical Activity Levels

  2023cites this paper
• Therapeutic exercise interventions in rat models of arthritis

  2023cites this paper
• Mechanotransduction pathways in articular chondrocytes and the emerging role of estrogen receptor-α

  2023cites this paper
• Influence of routine exercise on the peripheral immune system to prevent and alleviate pain

  2023cites this paper
• Study on the Role of MicroRNA-214 in the Rehabilitation of Cartilage in Mice with Exercise-Induced Traumatic Osteoarthritis

  2022cites this paper
• Exercise for Osteoarthritis: A Literature Review of Pathology and Mechanism

  2022cites this paper
• Effect of daily treadmill running exercise on masseter muscle nociception associated with social defeat stress in mice.

  2022cites this paper
• Training-Induced Hypoalgesia and its Potential Underlying Mechanisms.

  2022cites this paper
• Physical therapy as a promising treatment for osteoarthritis: A narrative review

  2022cites this paper
• Effects of Immobilization and Swimming on the Progression of Osteoarthritis in Mice

  2022cites this paper
• Benefits and Mechanisms of Exercise Training for Knee Osteoarthritis

  2021cites this paper
• Tai Chi for Improving Chronic Primary Musculoskeletal Pain: Protocol for a Systematic Review

  2021cites this paper
• Voluntary exercise blocks ongoing pain and diminishes bone remodeling while sparing protective mechanical pain in a rat model of advanced osteoarthritis pain.

  2021cites this paper
• Optimal parameters of blood flow restriction and resistance training on quadriceps strength and cross-sectional area and pain in knee osteoarthritis

  2021cites this paper
• Sodium Monoiodoacetate Dose-Dependent Changes in Matrix Metalloproteinases and Inflammatory Components as Prognostic Factors for the Progression of Osteoarthritis

  2021cites this paper
• Moderate-intensity treadmill running relieves motion-induced post-traumatic osteoarthritis mice by up-regulating the expression of lncRNA H19

  2021cites this paper
• Can we prevent chronic osteoarthritis pain? A view from the bench.

  2021cites this paper
• Therapeutic evaluation of galangin on cartilage protection and analgesic activity in a rat model of osteoarthritis

  2021cites this paper
• Mechanism of exercise-induced analgesia: what we can learn from physically active animals

  2020cites this paper
• Low-level cyclic tibial compression attenuates early osteoarthritis progression after joint injury in mice.

  2019cites this paper
• Endogenous Opiates and Behavior: 2017.

  2019cites this paper
• Females have greater susceptibility to develop ongoing pain and central sensitization in a rat model of temporomandibular joint pain.

  2019cites this paper
• The role of fat and inflammation in the pathogenesis and management of osteoarthritis.

  2018cites this paper
• Is Exercise Beneficial for Mental Health Impacts of Chronic Pain ?

  2018cites this paper
• Osteoarthritis pain. Recent advances and controversies

  2018cites this paper
• Investigating mechanisms of pain in Alzheimer's disease

  2018cites this paper
• Differences in 1‑year outcome after primary total hip and knee arthroplasty

  2018cites this paper
• The therapeutic effects of lipoxin A4 during treadmill exercise on monosodium iodoacetate‐induced osteoarthritis in rats

  2018cites this paper
• The Impact of Exercise in Rodent Models of Chronic Pain

  2018cites this paper
• l-Arginine and allopurinol supplementation attenuates inflammatory mediators in human osteoblasts-osteoarthritis cells.

  2018cites this paper
• Comparison of the effects of exercise with chondroitin sulfate on knee osteoarthritis in rabbits

  2018cites this paper
• Biomechanics and osteoarthritis : a novel rat model

  2017cites this paper