Co-Evolution of Transcriptional Silencing Proteins and the DNA Elements Specifying Their Assembly

Oliver A. Zill,Devin R. Scannell,Leonid Teytelman,J. Rine

Published 2010 in PLoS Biology

ABSTRACT

As shown by genetic assays in Saccharomyces interspecies hybrids, the co-evolution of heterochromatin assembly proteins with silencer elements allows transcriptional silencing functions to be maintained in rapidly evolving regions of the genome.

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