Mucin genes: structure, expression and regulation

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Glycoconjugate Journal

• Publication date

  1994-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF00731215PMID 7841791
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.

  1994cited by this paper
• Mucin coding sequences are remarkably conserved.

  1994cited by this paper
• Effect of retinoic acid on mucin gene expression in rat airways in vitro.

  1994cited by this paper
• Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines.

  1993cited by this paper
• Molecular cloning and sequencing of a canine tracheobronchial mucin cDNA containing a cysteine-rich domain.

  1993cited by this paper
• Quantitative ultrastructural analysis of the relationship between cell growth, shape change, and mucosecretory differentiation in cultured hamster tracheal epithelial cells exposed to retinoic acid.

  1993cited by this paper
• Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7).

  1993cited by this paper
• Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype.

  1993cited by this paper
• The basic science of gene therapy.

  1993cited by this paper
• Induction of G alpha i2-specific antisense RNA in vivo inhibits neonatal growth.

  1993cited by this paper
• Detection of the MUC2 apomucin tandem repeat with a mouse monoclonal antibody.

  1993cited by this paper
• Altered carbohydrate composition of salivary mucins from patients with cystic fibrosis and the adhesion of Pseudomonas aeruginosa.

  1993cited by this paper
• Increased adherence of Staphylococcus aureus from cystic fibrosis lungs to airway epithelial cells.

  1993cited by this paper
• Differential expression of the human mucin genes MUC1 to MUC5 in relation to growth and differentiation of different mucus-secreting HT-29 cell subpopulations.

  1993cited by this paper
• Mucin genes and the proteins they encode: structure, diversity, and regulation.

  1992cited by this paper
• P-domains as shuffled cysteine-rich modules in integumentary mucin C.1 (FIM-C.1) from Xenopus laevis. Polydispersity and genetic polymorphism.

  1992cited by this paper
• Hepatocyte nuclear factor 3 beta contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein

  1992cited by this paper
• Antibodies to the cytoplasmic domain of the MUC1 mucin show conservation throughout mammals.

  1992cited by this paper
• Glycopinion

  1992cited by this paper
• Characterization and purification of a novel transcriptional repressor from HeLa cell nuclear extracts recognizing the negative regulatory element region of human immunodeficiency virus-1 long terminal repeat.

  1992cited by this paper
• Tissue-specific expression of a human polymorphic epithelial mucin (MUC1) in transgenic mice.

  1992cited by this paper
• Mucin-type glycoproteins.

  1992cited by this paper
• The product of the human MUC1 gene when secreted by mouse cells transfected with the full-length cDNA lacks the cytoplasmic tail.

  1992cited by this paper
• Evidence for secretion of high molecular weight mucins by canine tracheal epithelial cells in primary culture: Effects of select secretagogues on mucin secretion

  1992cited by this paper
• cDNA for the carboxyl-terminal region of a rat intestinal mucin-like peptide.

  1992cited by this paper
• Mucins: structure, function, and role in pulmonary diseases.

  1992cited by this paper
• Differences in transformation activity between HPV-18 and HPV-16 map to the viral LCR-E6-E7 region.

  1991cited by this paper
• Cancer-associated mucins and mucin-type glycoproteins.

  1991cited by this paper
• Oligonucleotides as therapeutic agents.

  1991cited by this paper
• Human bronchus and intestine express the same mucin gene.

  1991cited by this paper
• Sulfated O-glycoproteins secreted by guinea pig trachea in organ culture.

  1991cited by this paper
• Porcine submaxillary mucin contains a cystine-rich, carboxyl-terminal domain in addition to a highly repetitive, glycosylated domain.

  1991cited by this paper
• Molecular cloning of rat intestinal mucin. Lack of conservation between mammalian species.

  1991cited by this paper
• Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism.

  1991cited by this paper
• In vitro toxicology and pharmacokinetics of antisense oligonucleotides.

  1991cited by this paper
• Mucin gene expression in rat airways following infection and irritation

  1991cited by this paper
• Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.

  1990cited by this paper
• An integumentary mucin (FIM-B.1) from Xenopus laevis homologous with von Willebrand factor.

  1990cited by this paper
• Cloning and cDNA sequence of a bovine submaxillary gland mucin-like protein containing two distinct domains.

  1990cited by this paper
• Human DNA TATA boxes and transcription initiation sites. A statistical study.

  1990cited by this paper
• The core polypeptide of cystic fibrosis tracheal mucin contains a tandem repeat structure. Evidence for a common mucin in airway and gastrointestinal tissue.

  1990cited by this paper
• Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

  1990cited by this paper
• Modification of mucin gene expression in the airways of rats exposed to sulfur dioxide

  1990cited by this paper
• Structure and expression of the human polymorphic epithelial mucin gene: an expressed VNTR unit.

  1990cited by this paper
• Covalent oligomerization of rat gastric mucin occurs in the rough endoplasmic reticulum, is N-glycosylation-dependent, and precedes initial O-glycosylation.

  1990cited by this paper
• The T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues.

  1990cited by this paper
• The serous cell.

  1990cited by this paper
• Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.

  1990cited by this paper
• Use of an antiserum against deglycosylated human mucins for cellular localization of their peptide precursors: antigenic similarities between bronchial and intestinal mucins.

  1989cited by this paper
• Alternative splicing in the control of gene expression.

  1989cited by this paper
• A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.

  1989cited by this paper
• Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism.

  1989cited by this paper
• A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats.

  1988cited by this paper
• Molecular cloning and characterization of cDNAs coding for apo-polysialoglycoprotein of rainbow trout eggs. Multiple mRNA species transcribed from multiple genes contain diverged numbers of exact 39-base (13-amino acid) repeats.

  1988cited by this paper
• Ribozymes and their medical implications.

  1988cited by this paper
• Carbohydrates as antigenic determinants of glycoproteins.

  1987cited by this paper
• Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium.

  1987cited by this paper
• Mucous glycoproteins: a gel of a problem.

  1985cited by this paper

• Study on MUC20 and Tumor Association

  2024cites this paper
• Mutational Impacts on the N and C Terminal Domains of the MUC5B Protein: A Transcriptomics and Structural Biology Study

  2023cites this paper
• Transcriptome analysis of female western flower thrips, Frankliniella occidentalis, exhibiting neo-panoistic ovarian development

  2022influential citation
• Mucin 5AC expression is common but unrelated to tumor progression in pancreatic adenocarcinoma

  2022cites this paper
• MUC5AC expression is linked to mucinous/endometroid subtype, absence of nodal metastasis and mismatch repair deficiency in ovarian cancer.

  2021cites this paper
• In silico analysis of glycosylation pattern in 5th-6th repeat sequence of reelin glycoprotein

  2021cites this paper
• An ovary-specific mucin is associated with choriogenesis mediated by prostaglandin signaling in Spodoptera exigua.

  2020cites this paper
• Elevated MUC5AC expression is associated with mismatch repair deficiency and proximal tumor location but not with cancer progression in colon cancer

  2020cites this paper
• O-glycosylation of Proteins

  2019cites this paper
• Untouchable genes in the human genome: Identifying ideal targets for cancer treatment.

  2019cites this paper
• Effectively preparing soluble ovomucin with high antiviral activity from egg white.

  2018cites this paper
• A Mucin-Like Protein of Planthopper Is Required for Feeding and Induces Immunity Response in Plants1[OPEN]

  2017cites this paper
• Estrogen induces two distinct cholesterol crystallization pathways by activating ERα and GPR30 in female mice

  2015cites this paper
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  2015cites this paper
• Prognostic value of Muc5AC in gastric cancer: A meta-analysis.

  2015cites this paper
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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
• Mucins and toll-like receptors: kith and kin in infection and cancer.

  2012cites this paper
• Mucin genes in gallstone disease.

  2012cites this paper
• The role of human breast milk mucus and mucins in HIV-AIDS

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• Histochemical profiles of mucins in the tracheal epithelium during the posthatching period of Japanese quail.

  2010cites this paper
• Stage dependent expression of MUC1 glycoprotein in gallbladder carcinoma

  2009cites this paper
• The isolation, purification, tissue localization and identification of a glycoprotein found in the crude mucus gel of patients with carcinoma of the stomach

  2008cites this paper
• Characterization of High Molecular Weight Mucins of Rabbit Bladder

  2008cites this paper
• Mucin overproduction in chronic inflammatory lung disease.

  2006cites this paper
• Multiple occurrences of spiggin genes in sticklebacks.

  2006cites this paper
• Evidence that gallbladder epithelial mucin enhances cholesterol cholelithogenesis in MUC1 transgenic mice.

  2006cites this paper
• Therapeutic approaches to mucus hypersecretion

  2005cites this paper
• Differential Mucin Subtype Regulation and Anti-inflammatory Effects of Inducible Nitric Oxide Synthase in Stimulated Airway Epithelial Cells in Vitro

  2005cites this paper
• Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1-/- mice.

  2004cites this paper
• Efficient synthesis of core 2 class glycosyl amino acids by one-pot glycosylation approach

  2004cites this paper
• Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1 (cid:1) / (cid:1) mice

  2004cites this paper
• Prediction of post‐translational glycosylation and phosphorylation of proteins from the amino acid sequence

  2004cites this paper
• Mucin macromolecules in normal, adenomatous, and carcinomatous colon: evidence for the neotransformation.

  2004cites this paper
• Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation 1

  2004cites this paper
• Role of MUC1 and MUC5AC expressions as prognostic indicators in gastric carcinomas

  2003cites this paper
• Production and characterisation of a recombinant scFv reactive with human gastrointestinal carcinomas

  2002influential citation
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• MUC2 Is a Molecular Marker for Pseudomyxoma Peritonei

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• Distribution and partial characterisation of IgG Fc binding protein in various mucin producing cells and body fluids

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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  1999cites this paper
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  1999cites this paper
• Bovine submaxillary mucin contains multiple domains and tandemly repeated non-identical sequences.

  1998cites this paper
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  1998cites this paper
• Two proteins of the Dictyostelium spore coat bind to cellulose in vitro.

  1998cites this paper
• Rhinovirus infection induces mucus hypersecretion.

  1998cites this paper
• Altered mucin expression is a field change that accompanies mucinous (colloid) breast carcinoma histogenesis.

  1998cites this paper
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  1997cites this paper
• Perspectives on the significance of altered glycosylation of glycoproteins in cancer

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  1997cites this paper
• Molecular cloning of a major human gall bladder mucin: complete C-terminal sequence and genomic organization of MUC5B.

  1997cites this paper
• Molecular Cloning and Sequencing of a Novel Invertebrate Intestinal Mucin cDNA*

  1997cites this paper
• The production of recombinant glycoproteins with special reference to simple eukaryotes including Dictyostelium discoideum.

  1997cites this paper
• Mucoglycoprotein hypersecretion in allergic rhinitis and cystic fibrosis.

  1997cites this paper
• A novel gastric‐cancer‐associated mucin antigen defined by a monoclonal antibody A3D4

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• An intestinal mucin is the target substrate for a baculovirus enhancin.

  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
• Purification and Structural Characterization of a Filamentous, Mucin-like Proteophosphoglycan Secreted by Leishmania Parasites*

  1996cites this paper
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  1996cites this paper
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  1996cites this paper
• MAUB Is a New Mucin Antigen Associated with Bladder Cancer (*)

  1996cites this paper
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
• Spontaneous release of submucosal gland serous and mucous cell macromolecules from human nasal explants in vitro.

  1996cites this paper
• A new monoclonal antibody (3D3) generated with human respiratory mucins and directed against Lewis determinants.

  1995cites this paper
• Biochemical composition of human saliva in relation to other mucosal fluids.

  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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