Lateral assembly of N-cadherin drives tissue integrity by stabilizing adherens junctions

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Journal of the Royal Society Interface

• Publication date

  2015-03-06

• Fields of study

  Biology, Medicine, Materials Science

• Identifiers
  DOI 10.1098/rsif.2014.1055PMID 25589573PMCID PMC4345472
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• R: A language and environment for statistical computing.

  2014cited by this paper
• High-resolution deep imaging of live cellular spheroids with light-sheet-based fluorescence microscopy

  2013cited by this paper
• Role of N-Cadherin cis and trans Interfaces in the Dynamics of Adherens Junctions in Living Cells

  2013influential reference
• Ideal, catch, and slip bonds in cadherin adhesion

  2012cited by this paper
• Cadherin point mutations alter cell sorting and modulate GTPase signaling

  2012influential reference
• Cadherin recognition and adhesion.

  2012cited by this paper
• Giving the right tug for migration: cadherins in tissue movements.

  2012cited by this paper
• Automated Detection and Segmentation of Synaptic Contacts in Nearly Isotropic Serial Electron Microscopy Images

  2011cited by this paper
• A complex of Protocadherin-19 and N-cadherin mediates a novel mechanism of cell adhesion

  2011cited by this paper
• The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.

  2011cited by this paper
• Kinetic Monte Carlo and cellular particle dynamics simulations of multicellular systems.

  2011cited by this paper
• Calcium-dependent dynamics of cadherin interactions at cell–cell junctions

  2011cited by this paper
• Dissipative particle dynamics simulations for biological tissues: rheology and competition

  2011cited by this paper
• Cadherin exits the junction by switching its adhesive bond

  2011influential reference
• Cooperativity between trans and cis interactions in cadherin-mediated junction formation

  2010cited by this paper
• Two-step adhesive binding by classical cadherins

  2010cited by this paper
• An evaluation of R2 as an inadequate measure for nonlinear models in pharmacological and biochemical research: a Monte Carlo approach

  2010cited by this paper
• Resolving cadherin interactions and binding cooperativity at the single-molecule level

  2009cited by this paper
• A Mathematical Model of Liver Cell Aggregation In Vitro

  2009cited by this paper
• 3D Multi-Cell Simulation of Tumor Growth and Angiogenesis

  2009cited by this paper
• Cadherin switching

  2008cited by this paper
• Three-dimensional preparation and imaging reveal intrinsic microtubule properties

  2007cited by this paper
• Restructuring dynamics of du 145 and LNCaP prostate cancer spheroids

  2007cited by this paper
• Activity-regulated N-cadherin endocytosis.

  2007cited by this paper
• Diversity of cell-mediated adhesions in breast cancer spheroids.

  2007cited by this paper
• The third dimension bridges the gap between cell culture and live tissue

  2007cited by this paper
• Dynamic analysis of hepatoma spheroid formation: roles of E-cadherin and β1-integrin

  2006cited by this paper
• CellProfiler: image analysis software for identifying and quantifying cell phenotypes

  2006cited by this paper
• A single-cell-based model of tumor growth in vitro: monolayers and spheroids

  2005cited by this paper
• Measuring cell adhesion forces of primary gastrulating cells from zebrafish using atomic force microscopy

  2005influential reference
• The differential adhesion hypothesis: a direct evaluation.

  2005cited by this paper
• Multicellular tumor spheroid in an off-lattice Voronoi-Delaunay cell model.

  2004cited by this paper
• The ins and outs of E-cadherin trafficking.

  2004cited by this paper
• Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function.

  2002cited by this paper
• Aggregation kinetics of well and poorly differentiated human prostate cancer cells.

  2002cited by this paper
• Depolarization Drives β-Catenin into Neuronal Spines Promoting Changes in Synaptic Structure and Function

  2002cited by this paper
• Dynamics of spheroid self-assembly in liquid-overlay culture of DU 145 human prostate cancer cells.

  2001cited by this paper
• Taking Cell-Matrix Adhesions to the Third Dimension

  2001cited by this paper
• An Algorithmic Introduction to Numerical Simulation of Stochastic Differential Equations

  2001cited by this paper
• Molecular modification of N-cadherin in response to synaptic activity.

  2000cited by this paper
• Structure-function analysis of cell adhesion by neural (N-) cadherin.

  1998cited by this paper
• Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies

  1997cited by this paper
• Formation of spheroid structures in a human colon carcinoma cell line involves a complex series of intercellular rearrangements.

  1997cited by this paper
• Morphogenetic roles of classic cadherins.

  1995cited by this paper
• The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules

  1994cited by this paper
• Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule.

  1990cited by this paper
• Cadherins: a molecular family important in selective cell-cell adhesion.

  1990cited by this paper
• Demonstration of an extracellular matrix in multicellular tumor spheroids.

  1984cited by this paper

• Matrix mechanics governs mechano-metabolic adaptation across cancer grades in bladder spheroids

  2025cites this paper
• Factors of bias in spheroid-based drug screening: Fabrication method, spheroid size, and cell viability.

  2025cites this paper
• Spheroid architecture strongly enhances miR-221/222 expression and promotes oxidative phosphorylation in an ovarian cancer cell line through a mechanism that includes restriction of miR-9 expression

  2024cites this paper
• Spheroid architecture strongly induces miR-221/222 expression and promotes oxidative phosphorylation and survival of mobile tumor cells through a mechanism that includes restriction of miR-9 expression

  2023cites this paper
• Selective Extracellular Matrix Guided Mesenchymal Stem Cell Self‐Aggregate Engineering for Replication of Meniscal Zonal Tissue Gradient in a Porcine Meniscectomy Model

  2023cites this paper
• Adherens junction: the ensemble of specialized cadherin clusters.

  2022cites this paper
• An Introduction to Image-Based Systems Biology of Multicellular Spheroids for Experimentalists and Theoreticians

  2019influential citation
• Novel Physics in Living Systems?

  2019cites this paper
• E-cadherin, actin, microtubules and FAK dominate different spheroid formation phases and important elements of tissue integrity

  2018influential citation
• Mouse ICM Organoids Reveal Three-Dimensional Cell Fate Clustering

  2018cites this paper
• Cadherin de-adhesion: consequences and mechanisms

  2017cites this paper
• Corrigendum: Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions

  2017cites this paper
• Sustained α-catenin Activation at E-cadherin Junctions in the Absence of Mechanical Force.

  2016cites this paper
• N-cadherin-functionalized polymer-tethered multi-bilayer: a cell surface-mimicking substrate to probe cellular mechanosensitivity.

  2016cites this paper
• Identifying the necrotic zone boundary in tumour spheroids with pair-correlation functions

  2016cites this paper
• Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions

  2016cites this paper