[Correlates of Cognitive Impairment of Rheumatic Disease: Systematic Review and Meta-analysis].

PURPOSE This study was conducted to synthesis the results of research on relationships of cognitive impairment with multi-dimensional correlates of rheumatic disease through a systematic literature review and meta-analysis. METHODS For the study purpose, 23 studies were selected through a systematic process of searching the literature. RESULTS The study results showed that among general characteristics, age and education were the variables having a significant relationship with cognitive impairment. Among health risk factors, obesity appeared to have a significant positive relationship with cognitive impairment. For past history, diabetes and hypertension were shown to have a significant positive relationship with cognitive impairment. It was noted also that aPL, one of the physiological factor, had significant association with cognitive impairment. None of the medication related factors had a significant relationship with cognitive impairment. Results showed that among disease related factors, disease activity had the highest relationship with cognitive impairment. Depression, among psychological factors, was the only variable having a significant relationship with cognitive impairment. CONCLUSION The findings indicate that the variables strongly impacting on cognitive impairment in rheumatic disease are depression and disease activity.

• Publication year

  2016

• Venue

  Journal of Korean Academy of Nursing

• Publication date

  2016-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.4040/jkan.2016.46.1.1PMID 26963410
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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