Ankrd 13A, 13B, and 13D constitute a family of ubiquitin-interacting motif (UIM)-bearing cytoplasmic proteins. They are anchored to the plasma membrane, where they recognize the Lys63-linked polyubiquitin chains tagged to ligand-activated EGF receptor and regulate the endocytosis of EGF receptor from the cell surface in mammalian cells.
The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane
Hidetaka Tanno,Teppei Yamaguchi,E. Goto,S. Ishido,M. Komada
Published 2012 in Molecular Biology of the Cell
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- Publication year
2012
- Venue
Molecular Biology of the Cell
- Publication date
2012-04-01
- Fields of study
Biology, Medicine
- Identifiers
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- Source metadata
Semantic Scholar, PubMed
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