Aprepitant loaded solid preconcentrated microemulsion for enhanced bioavailability: A comparison with micronized Aprepitant.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  European Journal of Pharmaceutical Sciences

• Publication date

  2015-10-12

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1016/j.ejps.2015.07.008PMID 26165621
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Statistical Modeling

  2020cited by this paper
• A novel approach for the development and optimization of self emulsifying drug delivery system using HLB and response surface methodology: application to fenofibrate encapsulation.

  2014cited by this paper
• What is the mechanism behind increased permeation rate of a poorly soluble drug from aqueous dispersions of an amorphous solid dispersion?

  2014cited by this paper
• Novel continuous flow technology for the development of a nanostructured aprepitant formulation with improved pharmacokinetic properties.

  2014cited by this paper
• Tamarindus indica pectin blend film composition for coating tablets with enhanced adhesive force strength.

  2014cited by this paper
• Development of solid self-nanoemulsifying granules (SSNEGs) of ondansetron hydrochloride with enhanced bioavailability potential.

  2013cited by this paper
• Optimized nanoemulsifying systems with enhanced bioavailability of carvedilol.

  2013cited by this paper
• Spray dried chitosan-EDTA superior microparticles as solid substrate for the oral delivery of amphotericin B.

  2013cited by this paper
• In Vitro Lipolysis and Intestinal Transport of β-Arteether-Loaded Lipid-Based Drug Delivery Systems

  2013cited by this paper
• Solidified Self-Nanoemulsifying Formulation for Oral Delivery of Combinatorial Therapeutic Regimen: Part I. Formulation Development, Statistical Optimization, and In Vitro Characterization

  2013cited by this paper
• Proposal of stability categories for nano-dispersions obtained from pharmaceutical self-emulsifying formulations.

  2013cited by this paper
• Preparation and in vitro Evaluation of Inclusion Complexes of Nelfinavir with Chemically Modified β-cyclodextrins

  2013cited by this paper
• Optimization of self‐microemulsifying drug delivery system for telmisartan using Box–Behnken design and desirability function

  2013cited by this paper
• Preparation and Pharmacokinetic Study of Aprepitant–Sulfobutyl Ether-β-Cyclodextrin Complex

  2013cited by this paper
• Transforming Lipid-Based Oral Drug Delivery Systems into Solid Dosage Forms: An Overview of Solid Carriers, Physicochemical Properties, and Biopharmaceutical Performance

  2013cited by this paper
• Statistical modeling, optimization and characterization of spray-dried solid self-microemulsifying drug delivery system using design of experiments.

  2013cited by this paper
• Nanoemulsions as self-emulsified drug delivery carriers for enhanced permeability of the poorly water-soluble selective β₁-adrenoreceptor blocker Talinolol.

  2012cited by this paper
• Crystalline Nanosuspensions as Potential Toxicology and Clinical Oral Formulations for BCS II/IV Compounds

  2012cited by this paper
• Optimized self nano-emulsifying systems of ezetimibe with enhanced bioavailability potential using long chain and medium chain triglycerides.

  2012cited by this paper
• Amorphous solid dispersion enhances permeation of poorly soluble ABT-102: true supersaturation vs. apparent solubility enhancement.

  2012cited by this paper
• A win-win solution in oral delivery of lipophilic drugs: supersaturation via amorphous solid dispersions increases apparent solubility without sacrifice of intestinal membrane permeability.

  2012cited by this paper
• A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting

  2012cited by this paper
• Improved oral bioavailability of poorly water-soluble indirubin by a supersaturatable self-microemulsifying drug delivery system

  2012cited by this paper
• Oral self emulsifying powder of lercanidipine hydrochloride: Formulation and evaluation

  2012cited by this paper
• The Twofold Advantage of the Amorphous Form as an Oral Drug Delivery Practice for Lipophilic Compounds: Increased Apparent Solubility and Drug Flux Through the Intestinal Membrane

  2012cited by this paper
• Rice Germ Oil as Multifunctional Excipient in Preparation of Self-Microemulsifying Drug Delivery System (SMEDDS) of Tacrolimus

  2012cited by this paper
• Starch-silicon dioxide coprecipitate as superdisintegrant: formulation and evaluation of fast disintegrating tablets

  2012cited by this paper
• Effects of solid carriers on the crystalline properties, dissolution and bioavailability of flurbiprofen in solid self-nanoemulsifying drug delivery system (solid SNEDDS).

  2012cited by this paper
• Study of cosurfactant effect on nanoemulsifying area and development of lercanidipine loaded (SNEDDS) self nanoemulsifying drug delivery system.

  2011cited by this paper
• Enhanced oral bioavailability of curcumin via a solid lipid-based self-emulsifying drug delivery system using a spray-drying technique.

  2011cited by this paper
• Inhibition of lipase-catalyzed hydrolysis of emulsified triglyceride oils by low-molecular weight surfactants under simulated gastrointestinal conditions.

  2011cited by this paper
• Nanocarrier for the enhanced bioavailability of a cardiovascular agent: in vitro, pharmacodynamic, pharmacokinetic and stability assessment.

  2011cited by this paper
• Solid self-nanoemulsifying drug delivery system (S-SNEDDS) containing phosphatidylcholine for enhanced bioavailability of highly lipophilic bioactive carotenoid lutein.

  2011cited by this paper
• Comparison of solid self-microemulsifying drug delivery system (solid SMEDDS) prepared with hydrophilic and hydrophobic solid carrier.

  2011cited by this paper
• Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans.

  2010cited by this paper
• Solid self-emulsifying nitrendipine pellets: preparation and in vitro/in vivo evaluation.

  2010cited by this paper
• In vitro and in vivo evaluation of self-microemulsifying drug delivery system of buparvaquone

  2010cited by this paper
• Lipid--an emerging platform for oral delivery of drugs with poor bioavailability.

  2009cited by this paper
• Formulation optimization and in situ absorption in rat intestinal tract of quercetin-loaded microemulsion.

  2009cited by this paper
• Preparation and Evaluation of Self-Microemulsifying Drug Delivery System Containing Vinpocetine

  2009cited by this paper
• Self-nanoemulsifying drug delivery systems of tamoxifen citrate: design and optimization.

  2009cited by this paper
• Understanding the Effect of API Properties on Bioavailability Through Absorption Modeling

  2008cited by this paper
• Packing polymorphism of a conformationally flexible molecule (aprepitant)

  2008cited by this paper
• Free flowing solid dispersions of the anti-HIV drug UC 781 with Poloxamer 407 and a maximum amount of TPGS 1000: investigating the relationship between physicochemical characteristics and dissolution behaviour.

  2008cited by this paper
• Rationalizing the selection of oral lipid based drug delivery systems by an in vitro dynamic lipolysis model for improved oral bioavailability of poorly water soluble drugs.

  2008cited by this paper
• Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of protein drugs: II. In vitro transport study.

  2008cited by this paper
• Quality by design: characterization of self-nano-emulsified drug delivery systems (SNEDDs) using ultrasonic resonator technology.

  2007cited by this paper
• Nanomedicines in the treatment of emesis during chemotherapy: focus on aprepitant

  2007cited by this paper
• Nanosizing--oral formulation development and biopharmaceutical evaluation.

  2007cited by this paper
• Enhancing the Bioavailability of Cyclosporine A Using Solid Dispersion Containing Polyoxyethylene (40) Stearate

  2006cited by this paper
• Inclusion Complexation of Anti-HIV Drug with β-Cyclodextrin

  2006cited by this paper
• Microemulsions as transdermal drug delivery vehicles.

  2006cited by this paper
• CYTOCHROME P450 3A4 IS THE MAJOR ENZYME INVOLVED IN THE METABOLISM OF THE SUBSTANCE P RECEPTOR ANTAGONIST APREPITANT

  2004cited by this paper
• The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human.

  2004cited by this paper
• Characterization and quantitation of aprepitant drug substance polymorphs by attenuated total reflectance fourier transform infrared spectroscopy.

  2003cited by this paper
• Melt extrusion: from process to drug delivery technology.

  2002cited by this paper
• Microemulsion-based media as novel drug delivery systems.

  2000cited by this paper

• Improving the Intestinal Permeability of Aprepitant via Self-Microemulsifying Delivery System: In Vitro Development and in Situ Permeation Assessment

  2025cites this paper
• Amorphous solid dispersion to facilitate the delivery of poorly water-soluble drugs: recent advances on novel preparation processes and technology coupling

  2024cites this paper
• Mucoadhesive aprepitant-loaded nanostructured lipid carriers containing sulfhydryl surfactant for enhanced oral drug bioavailability

  2024cites this paper
• Magnetic‐based photosensitizer to improve the efficiency of antimicrobial photodynamic therapy against mature dental caries‐related biofilms

  2023cites this paper
• Nanoparticle Engineering of Aprepitant Using Nano-by-Design (NbD) Approach

  2022cites this paper
• Atazanavir-Concentrate Loaded Soft Gelatin Capsule for Enhanced Concentration in Plasma, Brain, Spleen, and Lymphatics

  2022cites this paper
• Fabrication of an aprepitant nanosuspension using hydroxypropyl chitosan to increase the bioavailability.

  2022cites this paper
• In silico–assisted development of supersaturable preconcentrated isotropic mixture of atazanavir for augmenting biopharmaceutical performance in the presence of H2-receptor antagonist

  2022cites this paper
• Development of oral aprepitant-loaded chitosan–polyethylene glycol-coated cyclodextrin nanocapsules: formulation, characterization, and pharmacokinetic evaluation

  2021cites this paper
• Oral Drug Delivery Systems Based on Ordered Mesoporous Silica Nanoparticles for Modulating the Release of Aprepitant

  2021cites this paper
• Recent Applications of Mixture Designs in Beverages, Foods, and Pharmaceutical Health: A Systematic Review and Meta-Analysis

  2021cites this paper
• In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility

  2021cites this paper
• Magnetic-Responsive Photosensitizer Nanoplatform for Optimized Inactivation of Dental Caries-Related Biofilms: Technology Development and Proof of Principle.

  2021cites this paper
• Assessing the viability of carbamoylethyl pullulan-g-stearic acid based smart polymeric micelles for tumor targeting of raloxifene

  2021cites this paper
• Aprepitant Intravenous Emulsion Based on Ion Pairing/Phospholipid Complex for Improving Physical and Chemical Stability During Thermal Sterilization

  2020cites this paper
• Strategic approach to developing a self-microemulsifying drug delivery system to enhance antiplatelet activity and bioavailability of ticagrelor

  2019cites this paper
• FORMULATION AND EVALUATION OF FAST DISSOLVING TABLET OF APREPITANT BY USING NATURAL AND SYNTHETIC SUPERDISINTEGRANTS

  2019cites this paper
• Evaluation of Dissolution Enhancement of Aprepitant [0.95]Drug in Ternary Pharmaceutical Solid Dispersions with [0.95]Soluplus® and Poloxamer 188 Prepared by Melt Mixing

  2019cites this paper
• A spray dried Nelfinavir Mesylate particles for enhanced oral bioavailability: Systematic formulation optimization and in-vivo performance.

  2019cites this paper
• Evaluation of Dissolution Enhancement of Aprepitant Drug in Ternary Pharmaceutical Solid Dispersions with Soluplus® and Poloxamer 188 Prepared by Melt Mixing

  2019cites this paper
• Lipid based delivery of Efavirenz: An answer to its erratic absorption and food effect

  2018cites this paper
• Development of a New Aprepitant Liquisolid Formulation with the Aid of Artificial Neural Networks and Genetic Programming

  2017cites this paper
• Investigating the potential of Tamarindus indica pectin-chitosan conjugate for reducing recovery period in TNBS induced colitis.

  2017cites this paper
• Formulation and evaluation of self-emulsifying drug delivery system for nimodipine, a BCS class II drug

  2017cites this paper
• Microemulsion utility in pharmaceuticals: Implications for multi-drug delivery.

  2017cites this paper
• Quality-by-design based development of a self-microemulsifying drug delivery system to reduce the effect of food on Nelfinavir mesylate.

  2016cites this paper
• Development of aprepitant loaded orally disintegrating films for enhanced pharmacokinetic performance.

  2016cites this paper