Expression of GRP and its receptor in well-differentiated colon cancer cells correlates with the presence of focal adhesion kinase phosphorylated at tyrosines 397 and 407.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Journal of Histochemistry and Cytochemistry

• Publication date

  2003-04-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0016-5085(03)83093-7PMID 12871985
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: Independence from c-src or c-yes activation

  2006cited by this paper
• Quantitative Immunohistochemistry by Measuring Cumulative Signal Strength Accurately Measures Receptor Number

  2003cited by this paper
• The Focal Adhesion Kinase‐‐A Regulator of Cell Migration and Invasion

  2002cited by this paper
• Contribution of gastrin-releasing peptide and its receptor to villus development in the murine and human gastrointestinal tract.

  2002cited by this paper
• Expression of focal adhesion kinase in normal and pathologic human prostate tissues

  2002cited by this paper
• v-Src SH3-enhanced Interaction with Focal Adhesion Kinase at β1 Integrin-containing Invadopodia Promotes Cell Invasion*

  2002cited by this paper
• The case for gastrin-releasing peptide acting as a morphogen when it and its receptor are aberrantly expressed in cancer.

  2001cited by this paper
• Prognostic and predictive factors in primary breast cancer and their role in patient management: The Nottingham Breast Team.

  2001cited by this paper
• Reduced expression of focal adhesion kinase in liver metastases compared with matched primary human colorectal adenocarcinomas.

  2001cited by this paper
• Gastrin-releasing peptide is a mitogen and a morphogen in murine colon cancer.

  2000cited by this paper
• Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes.

  2000cited by this paper
• FAK integrates growth-factor and integrin signals to promote cell migration

  2000cited by this paper
• Quantitative Immunohistochemistry by Measuring Cumulative Signal Strength Using Commercially Available Software Photoshop and Matlab

  2000cited by this paper
• Histoclinical Analysis of Early Colorectal Cancer

  2000cited by this paper
• Prognostic value of nuclear morphometry in colorectal cancer

  1999cited by this paper
• Why do so many stimuli induce tyrosine phosphorylation of FAK?

  1999cited by this paper
• Aberrant expression of gastrin-releasing peptide and its receptor by well-differentiated colon cancers in humans.

  1999cited by this paper
• Focal adhesions.

  1999cited by this paper
• Metastasis-Associated genes and metastatic tumor progression.

  1998cited by this paper
• Nodal metastases: predictive factors.

  1998cited by this paper
• Convergent effects of growth factors, hormones, and fibronectin are necessary for the enterocyte differentiation of a colon adenocarcinoma cell line (HT29-D4).

  1998cited by this paper
• V. Gastrointestinal peptide signaling through tyrosine phosphorylation of focal adhesion proteins.

  1998cited by this paper
• Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation.

  1998cited by this paper
• Enterocytic differentiation of the human Caco‐2 cell line correlates with alterations in integrin signaling

  1998cited by this paper
• Prognostic significance of pathological and biological factors in hepatocellular carcinoma

  1998cited by this paper
• Grade, local stage and growth pattern as prognostic factors in carcinoma of the penis.

  1997cited by this paper
• Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK

  1995cited by this paper
• Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors.

  1995cited by this paper
• Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton.

  1993cited by this paper
• Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells.

  1993cited by this paper
• Prognostic value of tumor “budding” in patients with colorectal cancer

  1993cited by this paper
• Prognostic factors in colonic cancer

  1989cited by this paper
• Classification of normal colorectal mucosa and adenocarcinoma by morphometry

  1987cited by this paper
• The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases

  1986cited by this paper
• Importance of tumor pathology and morphology in patients with surgically resected colon cancer. Findings from the gastrointestinal tumor study group

  1986cited by this paper
• Local tumour invasion as a prognostic factor in colorectal cancer

  1981cited by this paper

• Emerging Role of Plant-Based Dietary Components in Post-Translational Modifications Associated with Colorectal Cancer

  2023cites this paper
• Roles of intercellular cell adhesion molecule-1 (ICAM-1) in colorectal cancer: expression, functions, prognosis, tumorigenesis, polymorphisms and therapeutic implications

  2022cites this paper
• Identification of a novel immune signature for optimizing prognosis and treatment prediction in colorectal cancer

  2021cites this paper
• FAK-Dependent Cell Motility and Cell Elongation

  2020cites this paper
• Endothelial cell activation on 3D-matrices derived from PDGF-BB-stimulated fibroblasts is mediated by Snail1

  2018cites this paper
• Independent prognostic genes and mechanism investigation for colon cancer

  2018cites this paper
• Gene Expression Analysis of the Concomitant Existence of Lymphovascular and Perineural Invasion in Colorectal Cancer

  2018cites this paper
• Expression of pY397 FAK promotes the development of non-small cell lung cancer

  2015cites this paper
• Receptor Protein-tyrosine Phosphatase α Regulates Focal Adhesion Kinase Phosphorylation and ErbB2 Oncoprotein-mediated Mammary Epithelial Cell Motility*

  2013cites this paper
• Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression.

  2013cites this paper
• Tools for protein posttranslational modifications analysis: FAK, a case study.

  2013cites this paper
• Role of gastrin-releasing peptides in breast cancer metastasis.

  2012cites this paper
• A Role for Nitric Oxide and for Nitric Oxide Synthases in Tumor Biology

  2012cites this paper
• Discovery of Novel Focal Adhesion Kinase Inhibitors Using a Hybrid Protocol of Virtual Screening Approach Based on Multicomplex-Based Pharmacophore and Molecular Docking

  2012cites this paper
• FAK is a Critical Regulator of Neuroblastoma Liver Metastasis

  2012cites this paper
• Gastrin-releasing peptide signaling alters colon cancer invasiveness via heterochromatin protein 1Hsβ.

  2011cites this paper
• Mechanisms by Which the Extracellular Matrix and Integrin Signaling Act to Regulate the Switch Between Tumor Suppression and Tumor Promotion

  2011cites this paper
• Focal adhesion kinase (FAK) と Insulin-like growth factor-I receptor (IGF-IR) に対するデュアルチロシンキナーゼ阻害剤の食道腺癌における抗腫瘍効果

  2010cites this paper
• Design of peptide-targeted liposomes containing nucleic acids.

  2010cites this paper
• Tumor-associated macrophages in clear cell renal cell carcinoma express both gastrin-releasing peptide and its receptor: a possible modulatory role of immune effectors cells

  2009cites this paper
• Paradoxical roles of FAK in tumor cell migration and metastasis

  2009cites this paper
• CFTR Cl– channel functional regulation by phosphorylation of focal adhesion kinase at tyrosine 407 in osmosensitive ion transporting mitochondria rich cells of euryhaline killifish

  2009cites this paper
• Expression of GRP and its receptor is associated with improved survival in patients with colon cancer

  2009cites this paper
• Inhibition of focal adhesion kinase as a potential therapeutic strategy for imatinib-resistant gastrointestinal stromal tumor

  2009cites this paper
• Spinal NMDA NR1 subunit expression following transient TNBS colitis.

  2009cites this paper
• Progress in researches about focal adhesion kinase in gastrointestinal tract.

  2009cites this paper
• Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms.

  2008cites this paper
• GRP-induced up-regulation of Hsp72 promotes CD16+/94+ natural killer cell binding to colon cancer cells causing tumor cell cytolysis

  2008cites this paper
• Dual Tyrosine Kinase Inhibitor for Focal Adhesion Kinase and Insulin-like Growth Factor-I Receptor Exhibits Anticancer Effect in Esophageal Adenocarcinoma In vitro and In vivo

  2008cites this paper
• Localization of FAK is related with colorectal carcinogenesis.

  2008cites this paper
• OipA plays a role in Helicobacter pylori‐induced focal adhesion kinase activation and cytoskeletal re‐organization

  2008cites this paper
• Concordant overexpression of p-FAK and p-ERK1/2 in extramammary Paget’s disease

  2008cites this paper
• DualTyrosine Kinase Inhibitor for Focal Adhesion Kinase and Insulin-like Growth Factor-IReceptor Exhibits Anticancer Effect in Esophageal Adenocarcinoma In vitro and In vivo

  2008cites this paper
• In vitro binding evaluation of 177Lu-AMBA, a novel 177Lu-labeled GRP-R agonist for systemic radiotherapy in human tissues

  2008cites this paper
• CYP27A1 and CYP24 Expression as a Function of Malignant Transformation in the Colon

  2007cites this paper
• Focal adhesion kinase and p53 signaling in cancer cells.

  2007cites this paper
• Histo-blood group antigen expression and proliferative activity of fibroblasts treated with dental monomers

  2007cites this paper
• Effect of Alloxan-Diabetes on Gastrin-Releasing Peptide (GRP) Immunoreactivity in the Gastrointestinal Tract, of Sprague Dawley Rats and How This May Affect Some of the Diabetic Complications

  2007cites this paper
• Gastrin-releasing peptide mediates its morphogenic properties in human colon cancer by upregulating intracellular adhesion protein-1 (ICAM-1) via focal adhesion kinase.

  2007cites this paper
• Focal adhesion kinase protein levels in gut epithelial motility.

  2006cites this paper
• Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer.

  2006cites this paper
• Gastrin-releasing peptide and cancer.

  2006cites this paper
• Consequence of gastrin-releasing peptide receptor activation in a human colon cancer cell line: a proteomic approach.

  2006cites this paper
• Triple treatment with octreotide, galanin and serotonin is a promising therapy for colorectal cancer.

  2005cites this paper
• Expression of Vitamin D Receptor and 25-Hydroxyvitamin D3-1α-Hydroxylase in Normal and Malignant Human Colon

  2005cites this paper
• The role of focal-adhesion kinase in cancer — a new therapeutic opportunity

  2005cites this paper
• Transient upregulation of GRP and its receptor critically regulate colon cancer cell motility during remodeling.

  2005cites this paper
• Levels of gastrin-releasing peptide and substance P in synovial fluid and serum correlate with levels of cytokines in rheumatoid arthritis

  2005cites this paper
• Stimulation of proliferation and migration of a colorectal cancer cell line by amidated and glycine-extended gastrin-releasing peptide via the same receptor.

  2004cites this paper
• Phosphorylation of focal adhesion kinase tyrosine 397 critically mediates gastrin‐releasing peptide's morphogenic properties

  2004cites this paper
• Transforming Growth Factor- (cid:1) Stimulates Intestinal Epithelial Focal Adhesion Kinase Synthesis via Smad- and p38-Dependent Mechanisms

  year unknowncites this paper