Effect of bisphosphonates on macrophagic THP-1 cell survival in bisphosphonate-related osteonecrosis of the jaw (BRONJ).

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Oral surgery, oral medicine, oral pathology and oral radiology

• Publication date

  2016-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.oooo.2015.10.008PMID 26725718
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Zoledronate but not denosumab suppresses macrophagic differentiation of THP-1 cells. An aetiologic model of bisphosphonate-related osteonecrosis of the jaw (BRONJ)

  2015cited by this paper
• Macrophages and bisphosphonate-related osteonecrosis of the jaw (BRONJ): evidence of local immunosuppression of macrophages in contrast to other infectious jaw diseases

  2015cited by this paper
• Epidemiology, clinical manifestations, risk reduction and treatment strategies of jaw osteonecrosis in cancer patients exposed to antiresorptive agents.

  2014cited by this paper
• [Effects of four bisphosphonates on macrophage phagocytosis: quantitative measurement by flow cytometry using high-fluorescence particles and human monocytic cell line THP-1].

  2014cited by this paper
• Medication-Related Osteonecrosis of the Jaw—2014 Update

  2014cited by this paper
• Bisphosphonate-related osteonecrosis of the jaws is caused by dental procedures that violate oral epithelium; this is no longer a mysterious disease.

  2014cited by this paper
• THP-1 cell line: an in vitro cell model for immune modulation approach.

  2014cited by this paper
• In vitro effects of bisphosphonates on chemotaxis, phagocytosis, and oxidative burst of neutrophil granulocytes

  2014cited by this paper
• American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw--2014 update.

  2014cited by this paper
• Zoledronic Acid Enhances Lipopolysaccharide-Stimulated Proinflammatory Reactions through Controlled Expression of SOCS1 in Macrophages

  2013cited by this paper
• Evolution and Etiopathogenesis of Bisphosphonates Induced Osteonecrosis of the Jaw

  2013cited by this paper
• Periapical Disease and Bisphosphonates Induce Osteonecrosis of the Jaws in Mice

  2013cited by this paper
• Zoledronate and pamidronate depress neutrophil functions and survival in mice

  2012cited by this paper
• Molecular profiling of oral microbiota in jawbone samples of bisphosphonate‐related osteonecrosis of the jaw

  2012cited by this paper
• The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature.

  2012cited by this paper
• Bisphosphonate-related osteonecrosis of the jaws--a review.

  2012cited by this paper
• YM‐175 induces apoptosis of human native monocyte‐lineage cells via inhibition of prenylation

  2012cited by this paper
• Biochemical and molecular mechanisms of action of bisphosphonates.

  2011cited by this paper
• Bisphosphonates inhibit phosphorylation of signal transducer and activator of transcription 3 and expression of suppressor of cytokine signaling 3: implications for their effects on innate immune function and osteoclastogenesis.

  2011cited by this paper
• Perioperative antibiotic regimen in rats treated with pamidronate plus dexamethasone and subjected to dental extraction: a study of the changes in the jaws.

  2011cited by this paper
• Bisphosphonates: the first 40 years.

  2011cited by this paper
• Osteonecrosis of the jaw and the role of macrophages.

  2011cited by this paper
• Zoledronic acid modulates maturation of human monocyte-derived dendritic cells

  2011cited by this paper
• Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings

  2010cited by this paper
• Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages.

  2010cited by this paper
• Osteonecrosis of the jaw: who gets it, and why?

  2009cited by this paper
• Fluorescent Risedronate Analogues Reveal Bisphosphonate Uptake by Bone Marrow Monocytes and Localization Around Osteocytes In Vivo

  2009cited by this paper
• American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws--2009 update.

  2009cited by this paper
• Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP

  2009cited by this paper
• Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation?

  2009cited by this paper
• Identification of microbial biofilms in osteonecrosis of the jaws secondary to bisphosphonate therapy.

  2008cited by this paper
• Comparative effects of five bisphosphonates on apoptosis of macrophage cells in vitro.

  2007cited by this paper
• Clodronate acts on human osteoclastic cell proliferation, differentiation and function in a bioreversible manner.

  2007cited by this paper
• Osteonecrosis of the jaws in patients treated with bisphosphonates - histomorphologic analysis in comparison with infected osteoradionecrosis.

  2006cited by this paper
• Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite.

  2006cited by this paper
• A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen‐containing bisphosphonates

  2006cited by this paper
• Effect of pamidronate on the stimulation of macrophage TNF‐α release by ultra‐high‐molecular‐weight polyethylene particles: a role for apoptosis

  2003cited by this paper
• A pharmacokinetic and pharmacodynamic model for intravenous bisphosphonate (pamidronate) in osteoporosis

  2002cited by this paper
• Essential Requirement of Antigen Presentation by Monocyte Lineage Cells for the Activation of Primary Human γδ T Cells by Aminobisphosphonate Antigen1

  2001cited by this paper
• Essential requirement of antigen presentation by monocyte lineage cells for the activation of primary human gamma delta T cells by aminobisphosphonate antigen.

  2001cited by this paper
• Influence of cyclic intravenous pamidronate on proinflammatory monocytic cytokine profiles and bone density in rheumatoid arthritis treated with low dose prednisolone and methotrexate.

  2001cited by this paper
• Chemical and biological prerequisites for novel bisphosphonate molecules: results of comparative preclinical studies.

  2001cited by this paper
• Gamma/delta T-cell stimulation by pamidronate.

  1999cited by this paper
• Bisphosphonates induce apoptosis in mouse macrophage‐like cells in vitro by a nitric oxide‐independent mechanism

  1996cited by this paper
• Inhibition of antigen‐presenting cell function by alendronate in vitro

  1995cited by this paper
• Pharmacokinetics of pamidronate in patients with bone metastases.

  1992cited by this paper
• In vitro effect of (3-amino-1-hydroxypropylidene)-1,1-bisphosphonic acid (APD) on the function of mononuclear phagocytes in lymphocyte proliferation.

  1982cited by this paper
• Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester.

  1982cited by this paper

• Fluvastatin enhances healing of medication−related osteonecrosis of the jaw (MRONJ) via macrophage polarization in a rat MRONJ−like model

  2025cites this paper
• Bisphosphonates loaded nanoparticles in microparticles: a potential macrophage targeting and repolarizing drug delivery system

  2025cites this paper
• Aseptic necrosis of the jaw when using bisphosphonates: etiopathogenetic and preventive aspects

  2025cites this paper
• Etiopathogenesis of medication-related osteonecrosis of the jaws: a review

  2024cites this paper
• Bisphosphonates and osteonecrosis of the jaws: Clinical and forensic aspects.

  2023cites this paper
• Electron microscopic analysis of necrotic bone and failed implant surface in a patient with medication-related osteonecrosis of the jaw

  2023cites this paper
• Impacts of bisphosphonates on the bone and its surrounding tissues: mechanistic insights into medication-related osteonecrosis of the jaw

  2022cites this paper
• Medication‐related osteonecrosis of the jaw: A literature review and update

  2022cites this paper
• Macrophage Involvement in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Comprehensive, Short Review

  2022cites this paper
• Ibandronate sodium and zoledronate sodium in the treatment of senile osteoporosis: efficacy, impact on quality of life and cost-effectiveness analysis.

  2021cites this paper
• Extensive protein expression changes induced by pamidronate in RAW 264.7 cells as determined by IP-HPLC

  2020cites this paper
• Inhibition of macrophage viability by bound and free bisphosphonates.

  2019cites this paper
• Gingival fibroblasts and medication-related osteonecrosis of the jaw: Results by real-time and wound healing in vitro assays.

  2019cites this paper
• Full blood counts are not predictive of the risk of medication-related osteonecrosis of the jaws: a case-control study.

  2019cites this paper
• Alteration of macrophage viability, differentiation, and function by bisphosphonates.

  2018cites this paper
• Osteoblast-like cells with different embryologic origins behave differently in increasing zoledronic acid concentrations: a pilot study in pigs.

  2017cites this paper
• Hyperbaric oxygen therapy and osteonecrosis.

  2017cites this paper
• Modified SEM Preparation for THP-1 Monocytes

  2017cites this paper
• Pamidronate Disodium Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells In Vitro.

  2017cites this paper
• Wound healing protein profiles in the postoperative exudate of bisphosphonate-related osteonecrosis of mandible

  2017cites this paper
• Impact of Soft Tissue Pathophysiology in the Development and Maintenance of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ)

  2016cites this paper
• Medication related osteonecrosis of the jaws. Literature review

  year unknowncites this paper