Electrostatic Edge Instability of Lipid Membranes

This paper considers the effect of electrostatics on the stability of a charged membrane. We show that at low ionic strength and high surface charge density, repulsion between charges on the membrane renders it unstable to the formation of holes. A free straight edge is unstable to modulations with wavelength longer than the Debye screening length. Hence at low ionic strength, membranes will disintegrate into vesicles. We use these results to interpret stable holes in red blood cell ghosts (Steck et. al., Science 168:255(1970)).

• Publication year

  1998

• Venue

  Physical Review Letters

• Publication date

  1998-12-17

• Fields of study

  Biology, Materials Science, Physics

• Identifiers
  DOI 10.1103/PhysRevLett.82.1598arXiv physics/9812033
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Proc. Nat. Acad. Sei

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