Community deworming alleviates geohelminth-induced immune hyporesponsiveness

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2016-10-17

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1073/pnas.1604570113PMID 27791067PMCID PMC5098677
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Deworming drugs for soil‐transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin, and school performance

  2015cited by this paper
• Impact of Malaria Preexposure on Antiparasite Cellular and Humoral Immune Responses after Controlled Human Malaria Infection

  2015cited by this paper
• Parallels between cancer and infectious disease.

  2014influential reference
• Helminth therapy or elimination: epidemiological, immunological, and clinical considerations.

  2014cited by this paper
• Immune activation alters cellular and humoral responses to yellow fever 17D vaccine.

  2014cited by this paper
• The Effect of Three-Monthly Albendazole Treatment on Malarial Parasitemia and Allergy: A Household-Based Cluster-Randomized, Double-Blind, Placebo-Controlled Trial

  2013influential reference
• Combination checkpoint blockade--taking melanoma immunotherapy to the next level.

  2013influential reference
• Posttreatment Changes in Cytokines Induced by Schistosoma mansoni Egg and Worm Antigens: Dissociation of Immunity- and Morbidity-Associated Type 2 Responses

  2013influential reference
• Helminth–host immunological interactions: prevention and control of immune‐mediated diseases

  2012cited by this paper
• Helminth Infections and Host Immune Regulation

  2012cited by this paper
• Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin and school performance.

  2012cited by this paper
• Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura.

  2012influential reference
• Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway

  2011influential reference
• Modulation of Specific and Allergy-Related Immune Responses by Helminths

  2011influential reference
• Filarial Infection Suppresses Malaria-Specific Multifunctional Th1 and Th17 Responses in Malaria and Filarial Coinfections

  2011influential reference
• Induction of CD4+CD25+FOXP3+ Regulatory T Cells during Human Hookworm Infection Modulates Antigen-Mediated Lymphocyte Proliferation

  2011cited by this paper
• Efficacy of single and double doses of albendazole and mebendazole alone and in combination in the treatment of Trichuris trichiura in school-age children in Uganda.

  2011influential reference
• Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum

  2010cited by this paper
• Does treatment of intestinal helminth infections influence malaria? Background and methodology of a longitudinal study of clinical, parasitological and immunological parameters in Nangapanda, Flores, Indonesia (ImmunoSPIN Study)

  2010cited by this paper
• Schistosomiasis Coinfection in Children Influences Acquired Immune Response against Plasmodium falciparum Malaria Antigens

  2010influential reference
• Long-term periodic anthelmintic treatments are associated with increased allergen skin reactivity

  2010influential reference
• Review series on helminths, immune modulation and the hygiene hypothesis: The broader implications of the hygiene hypothesis

  2009influential reference
• Reduced helminth burden increases allergen skin sensitization but not clinical allergy: a randomized, double‐blind, placebo‐controlled trial in Vietnam

  2009influential reference
• Responses to malarial antigens are altered in helminth-infected children.

  2009influential reference
• Early Exposure of Infants to GI Nematodes Induces Th2 Dominant Immune Responses Which Are Unaffected by Periodic Anthelminthic Treatment

  2009cited by this paper
• Human type 1 and 17 responses in latent tuberculosis are modulated by coincident filarial infection through cytotoxic T lymphocyte antigen-4 and programmed death-1.

  2009influential reference
• Repeated treatments with albendazole enhance Th2 responses to Ascaris Lumbricoides, but not to aeroallergens, in children from rural communities in the Tropics.

  2008influential reference
• Helminth infections: the great neglected tropical diseases.

  2008cited by this paper
• CTLA-4 in Filarial Infections: Implications for a Role in Diminished T Cell Reactivity

  2003cited by this paper
• Nutrition and the immune system from birth to old age

  2002cited by this paper
• Effect of deworming on human T cell responses to mycobacterial antigens in helminth‐exposed individuals before and after bacille Calmette–Guérin (BCG) vaccination

  2001influential reference
• Albendazole treatment of children with ascariasis enhances the vibriocidal antibody response to the live attenuated oral cholera vaccine CVD 103-HgR.

  2000cited by this paper
• Immunology and inflammation

  1996cited by this paper
• The acquisition and loss of antigen-specific cellular immune responsiveness in acute and chronic schistosomiasis in man.

  1978influential reference

• Developmental plasticity enables an intestinal tapeworm to adapt to dietary stress.

  2026cites this paper
• The endemic dilemma: why whole sporozoite malaria vaccine efficacy falls in the field.

  2026cites this paper
• Experimental evolution of Plasmodium yoelii in single and helminth-coinfected mice

  2025cites this paper
• Prevalence and risk factors for parasitic infections among internally displaced persons in the North-Central Geopolitical Zone of Nigeria

  2025cites this paper
• Parasites influence the physiology and personality in a small mammal (Ochotona curzoniae)

  2025cites this paper
• Asthma Inception: Epidemiologic Risk Factors and Natural History Across the Life Course

  2024cites this paper
• Lifestyle score is associated with cellular immune profiles in healthy Tanzanian adults

  2024cites this paper
• Humans seropositive for Trypanosoma cruzi co-infected with intestinal helminths have higher infectiousness, parasitaemia and Th2-type response in the Argentine Chaco

  2024cites this paper
• The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response.

  2024cites this paper
• Exploring the impact of epidemiological and clinical factors on the progression of canine leishmaniosis by statistical and whole genome analyses: from breed predisposition to comorbidities.

  2024cites this paper
• Treatment of pregnant mice with ABZ had no effect on the immune response of their offspring infected with Trichinella spiralis.

  2023cites this paper
• Infection with soil-transmitted helminths and their impact on coinfections

  2023cites this paper
• Metabolic potential of gut microbiota in helminth infections as a way to achieve bronchial asthma control

  2023cites this paper
• Immunological factors linked to geographical variation in vaccine responses

  2023cites this paper
• Regulatory T cells in parasite infections: susceptibility, specificity and specialisation.

  2023cites this paper
• Trained immunity in type 2 immune responses

  2022cites this paper
• Anthelmintic Treatment in Growing Cattle: A Preliminary Study on the Effect of Ricobendazole on the Fecal Microbiome

  2022cites this paper
• Immunological Interactions between Intestinal Helminth Infections and Tuberculosis

  2022cites this paper
• Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased protective efficacy

  2022cites this paper
• Effects of helminths on the human immune response and the microbiome

  2022cites this paper
• Chronic Immune Activation and CD4+ T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy

  2021cites this paper
• The impact of Opisthorchis felineus infection and praziquantel treatment on the intestinal microbiota in children.

  2021cites this paper
• Helminth infection is associated with dampened cytokine responses to viral and bacterial stimulations in Tsimane forager-horticulturalists

  2021cites this paper
• The yin and yang of human soil-transmitted helminth infections.

  2021cites this paper
• Joint Models for Repeatedly Measured Compositional and Normally Distributed Outcomes

  2021cites this paper
• Helminth infection is associated with dampened cytokine responses to viral and bacterial stimulations in Tsimane hunter-horticulturalists

  2021cites this paper
• Helminth–virus interactions: determinants of coinfection outcomes

  2021cites this paper
• Gut Helminth Infection-Induced Immunotolerance and Consequences for Human Papillomavirus Persistence.

  2021cites this paper
• Immunological Considerations for Schistosoma Vaccine Development: Transitioning to Endemic Settings

  2021cites this paper
• IL-4-induced hysteresis in naïve T cell activation

  2020cites this paper
• Regulation of immunity and allergy by helminth parasites

  2020cites this paper
• Helminth infections drive heterogeneity in human type 2 and regulatory cells

  2020cites this paper
• Harnessing the gut microbiome in the fight against anthelminthic drug resistance.

  2020cites this paper
• Routine deworming during antenatal care decreases risk of neonatal mortality and low birthweight: A retrospective cohort of survey data

  2020cites this paper
• Immunity to Soil-Transmitted Helminths: Evidence From the Field and Laboratory Models

  2020cites this paper
• Twenty-year economic impacts of deworming

  2020cites this paper
• What Can Parasites Tell Us About the Pathogenesis and Treatment of Asthma and Allergic Diseases

  2020cites this paper
• Gross ways to live long: Parasitic worms as an anti-inflammaging therapy?

  2020cites this paper
• TRICHINELLA SPIRALIS AS A POTENTIAL THERAPEUTIC AGENT: FROM A RISKY DISEASE TO A FRIEND

  2020cites this paper
• Immunoparasitology: A Unique Interplay Between Host and Pathogen

  2020cites this paper
• Administration of anti‐CTLA‐4 monoclonal antibody augments protective immunity induced by Schistosoma japonicum glutathione‐S‐transferase

  2019cites this paper
• Helminth-allergy associations in rural and urban Uganda: insights from antibody studies

  2019cites this paper
• Effects Of Diet And Parasites On The Gut Microbiota Of Diverse Sub-Saharan Africans

  2019cites this paper
• Helminth Infections Suppress the Efficacy of Vaccination against Seasonal Influenza.

  2019cites this paper
• The Effect of Gut Microbiome Composition on Human Immune Responses: An Exploration of Interference by Helminth Infections

  2019cites this paper
• Safety and efficacy of helminth treatment in relapsing-remitting multiple sclerosis: Results of the HINT 2 clinical trial

  2019cites this paper
• Inflammatory and regulatory CCL and CXCL chemokine and cytokine cellular responses in patients with patent Mansonella perstans filariasis

  2019cites this paper
• Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas

  2019cites this paper
• Variation in Local and Systemic Pro-Inflammatory Immune Markers of Wild Wood Mice after Anthelmintic Treatment

  2019cites this paper
• Helminth Therapy - From the Parasite Perspective.

  2019cites this paper
• Atrophy of skin-draining lymph nodes predisposes for impaired immune responses to secondary infection in mice with chronic intestinal nematode infection

  2018cites this paper
• Impact of intestinal worms on distal immune response and control of co-infections

  2018cites this paper
• Identification and characterization of HIV positive Ethiopian elite controllers in both Africa and Israel

  2018cites this paper
• Schistosomiasis Burden and Its Association With Lower Measles Vaccine Responses in School Children From Rural Cameroon

  2018cites this paper
• Soil‐transmitted helminth parasites and allergy: Observations from Ecuador

  2018cites this paper
• The Impact of Intensive Versus Standard Anthelminthic Treatment on Allergy-related Outcomes, Helminth Infection Intensity, and Helminth-related Morbidity in Lake Victoria Fishing Communities, Uganda: Results From the LaVIISWA Cluster-randomized Trial

  2018influential citation
• Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia

  2018cites this paper
• Worms: Pernicious parasites or allies against allergies?

  2018cites this paper
• Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation

  2018cites this paper
• Plasmodium and intestinal parasite perturbations of the infected host’s inflammatory responses: a systematic review

  2018cites this paper
• Competing for blood: the ecology of parasite resource competition in human malaria-helminth co-infections.

  2018cites this paper
• Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia

  2018cites this paper
• The frontline of controlled human malaria infections: A report from the controlled human infection models Workshop in Leiden University Medical Centre 5 May 2016.

  2017cites this paper
• Zoonotic intestinal helminths interact with the canine immune system by modulating T cell responses and preventing dendritic cell maturation

  2017cites this paper
• Global issues in allergy and immunology: Parasitic infections and allergy

  2017cites this paper
• CHAPTER summarizing discussion Adapted from : Helminths , hygiene hypothesis and type 2 diabetes

  2017cites this paper
• Helminths, hygiene hypothesis and type 2 diabetes

  2017cites this paper
• Effect of Early‐Life Geohelminth Infections on the Development of Wheezing at 5 Years of Age

  2017cites this paper
• Helminth Immunomodulation in Autoimmune Disease

  2017cites this paper
• Parasite Mediated Protection Against Allergy

  2017cites this paper
• The effect of three‐monthly albendazole treatment on Th2 responses: Differential effects on IgE and IL‐5

  2017cites this paper
• Early-life infectious disease exposure, the “hygiene hypothesis”, and lifespan: evidence from hookworm ∗

  year unknowncites this paper