Arachidonic acid metabolism in glutathione-deficient macrophages.

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1982-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1073/PNAS.79.5.1621PMID 6803245PMCID PMC346027
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Depletion of glutathione by inhibition of biosynthesis.

  1981cited by this paper
• Depletion of glutathione selectively inhibits synthesis of leukotriene C by macrophages.

  1981cited by this paper
• Prostaglandin synthesis by macrophages requires a specific receptor-ligand interaction.

  1980cited by this paper
• Regulation of arachidonic acid metabolites in macrophages

  1980cited by this paper
• Mouse peritoneal macrophages release leukotriene C in response to a phagocytic stimulus.

  1980cited by this paper
• Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine.

  1980cited by this paper
• Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds.

  1979cited by this paper
• Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187.

  1979cited by this paper
• Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids.

  1979cited by this paper
• Structure of leukotriene C. Identification of the amino acid part.

  1979cited by this paper
• Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

  1979cited by this paper
• Regulation of prostaglandin synthesis and of the selective release of lysosomal hydrolases by mouse peritoneal macrophages.

  1978cited by this paper
• Characterization of the macrophage receptro for complement and demonstration of its functional independence from the receptor for the Fc portion of immunoglobulin G

  1975cited by this paper
• Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets.

  1974cited by this paper
• Extraction of Prostaglandins from Human Blood

  1971cited by this paper
• Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues.

  1969cited by this paper
• THE DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES

  1965cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Chapter 17 Prostate Cancer , Inflammation and Antioxidants

  2018cites this paper
• Calcium-independent phospholipases A2 in murine osteoblastic cells and their inhibition by bromoenol lactone: impact on arachidonate dynamics and prostaglandin synthesis

  2016cites this paper
• Combination of Paracetamol and the Glutathione Depleting Agent Buthionine Sulfoximine Show Differential Effect on Liver Cancer Cells and Normal Hepatocytes

  2016cites this paper
• Drug-induced pulmonary disease.

  2015cites this paper
• Oxidative Stress and Dietary Interventions in Autism: Exploring the Role of Zinc, Antioxidant Enzymes and Other Micronutrients in the Neurobiology of Autism

  2014cites this paper
• with Increased Uptake of Glutathione Burst in Human Monocytes Is Associated The Phagocytosis-Associated Respiratory

  2013cites this paper
• Prostate Cancer, Inflammation and Antioxidants

  2013cites this paper
• The role of mesenchymal stem cells in anti-cancer drug resistance and tumour progression

  2012cites this paper
• Effets des sensibilisants sur la synthèse de la prostaglandine E2 : Mécanismes et intérêt dans la prédiction de l’allergie de contact

  2012cites this paper
• Histoplasma capsulatum secreted γ‐glutamyltransferase reduces iron by generating an efficient ferric reductant

  2008cites this paper
• Molecular and cellular aspects of thiol-disulfide exchange.

  2006cites this paper
• Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms.

  2004cites this paper
• An Appreciation of the Physician-scientist the Formation of Lysosomes in Cultured Mouse Peritoneal Macrophages

  2003cites this paper
• The Phagocytosis-Associated Respiratory Burst in Human Monocytes Is Associated with Increased Uptake of Glutathione1

  2000cites this paper
• Effect of intracellular glutathione on the production of prostaglandin D2 in RBL-2H3 cells oxidized by tert-butyl hydroperoxide.

  1999cites this paper
• Gender and maturation affect glutathione status in human neonatal tissues.

  1997cites this paper
• Escherichia coli endotoxin-mediated endothelial injury is modulated by glutathione ethyl ester.

  1995cites this paper
• Nucleotide changes in oxidatively stressed lymphocytes.

  1995cites this paper
• Phospholipid metabolism of lymphocytes with inhibited glutathione synthesis using L-buthionine-S,R-sulfoximine.

  1995cites this paper
• Zanvil Alexander Cohn 1926-1993

  1994cites this paper
• Prostacyclin elevation following glutathione depletion in vivo. Possible threshold dependency in liver and lung.

  1993cites this paper
• Diminished arachidonic acid metabolite release by bovine alveolar macrophages exposed to surface-modified silica.

  1992cites this paper
• Effect of glutathione depletion on tissue and plasma prostacyclin and thromboxane in rats.

  1992cites this paper
• Glutathione depletion and rabbit renal medulla 6-ketoPGF1 alpha and TxB2: levels in vivo and following homogenate incubation in vitro.

  1992cites this paper
• Effect of diethyl maleate on glutathione, hepatic and renal cortical perfusion, and portal 6-ketoPGF1 alpha and TxB2 levels in swine.

  1992cites this paper
• Regulation of endothelial cell prostaglandin synthesis by glutathione.

  1991cites this paper
• Indomethacin attenuation of hepatic perfusion and plasma 6-ketoPGF1 alpha elevations following glutathione depletion in rabbits.

  1991cites this paper
• Transformation of 5-hydroperoxyeicosatetraenoic acid into dihydroxy- and cysteinyl-leukotrienes by rat hepatocytes: effects of glutathione.

  1991cites this paper
• Urinary leukotriene E4 in patients with asthma. Effect of airways reactivity and sodium cromoglycate.

  1991cites this paper
• Comparison of arachidonate metabolism by alveolar macrophages from bighorn and domestic sheep

  1991cites this paper
• Effect of glutathione manipulation on prostaglandin synthesis in renal medullary homogenates.

  1991cites this paper
• Indomethacin attenuation of celiac blood flow hyperemia following glutathione depletion.

  1990cites this paper
• Concentration-activity profile of the modulation of cyclooxygenase product formation by reduced glutathione in microsomal fractions from the goat lung.

  1990cites this paper
• The effects of different silicas on arachidonic acid metabolism in alveolar macrophages.

  1990cites this paper
• Influence of Extracellular Calcium on the Metabolism of Arachidonic Acid in Alveolar Macrophages

  1990cites this paper
• The effect of endotoxin on 1,2‐dimethylhydrazine‐induced colonic tumors in rats

  1990cites this paper
• Inhibition of alveolar macrophage 5-lipoxygenase metabolism by auranofin.

  1989cites this paper
• Stimulus-specific production of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by bovine alveolar macrophages

  1989cites this paper
• Stimulation of arachidonic acid metabolism in silica-exposed alveolar macrophages.

  1989cites this paper
• Inhibition of fibrinolysis by cellular glutathione depletion in the rabbit.

  1989cites this paper
• Cell cycle progression of glutathione-depleted human peripheral blood mononuclear cells is inhibited at S phase.

  1989cites this paper
• Modulation of endoperoxide product levels and cyclophosphamide-induced injury by glutathione repletion.

  1989cites this paper
• Virus‐Induced Enhancement of Arachidonate Metabolism by Bovine Alveolar Macrophages In Vitro

  1989cites this paper
• Inhibition of granulocyte-mediated release of oxygen free radicals following glutathione depletion.

  1988cites this paper
• Production of lipoxygenase metabolites of eicosapentaenoic acid by bovine alveolar macrophages in vitro

  1988cites this paper
• Studies on the mechanism of ethanol-induced gastric damage in rats.

  1988cites this paper
• Hydrogen-peroxide-induced arachidonic acid metabolism in the rat alveolar macrophage.

  1988cites this paper
• Glutathione status and cadmium neurotoxicity: studies in discrete brain regions of growing rats.

  1988cites this paper
• Radioimmunoassay of Leukotrienes and Other Lipoxygenase Products of Arachidonate

  1987cites this paper
• Drug-induced pulmonary disease.

  1987cites this paper
• Modulation of alveolar macrophage-derived 5-lipoxygenase products by the sulfhydryl reactant, N-ethylmaleimide.

  1987cites this paper
• Extraction and purification of arachidonic acid metabolites from cell cultures.

  1987cites this paper
• Near-total glutathione depletion and age-specific cataracts induced by buthionine sulfoximine in mice.

  1986cites this paper
• Arachidonic acid metabolism in bovine alveolar macrophages

  1986influential citation
• Enhancement of intracellular glutathione promotes lymphocyte activation by mitogen.

  1986cites this paper
• [Possible role of glutathione peroxidase in the regulation of collagenase activity].

  1986cites this paper
• Biochemistry and pharmacology of renal arachidonic acid metabolism.

  1986cites this paper
• Biochemistry and Pharmacology of Renal Arachidonic Acid Metabolism

  1986cites this paper
• Redox status and pulmonary vascular reactivity.

  1985cites this paper
• The fall and rise of cellular glutathione levels: enzyme-based approaches.

  1985cites this paper
• The role of glutathione in lymphocyte activation. I. Comparison of inhibitory effects of buthionine sulfoximine and 2-cyclohexene-1-one by nuclear size transformation.

  1985cites this paper
• Leukotrienes: biosynthesis, metabolism, and analysis.

  1985cites this paper
• Evidence for differential activation of arachidonic acid metabolism in formylpeptide- and macrophage-activation-factor-stimulated guinea-pig macrophages.

  1985cites this paper
• Methods for the selective modification of glutathione metabolism and study of glutathione transport.

  1985cites this paper
• Protection of the gastroduodenal mucosa by prostaglandins.

  1985cites this paper
• The Synthesis of Arachidonic Acid Oxygenation Products by Macrophages

  1985cites this paper
• Effects on Glucose-induced Insulin Secretion of Lipoxygenase-derived Metabolites of Arachidonic Acid

  1984cites this paper
• Reduced glutathione modulates the arachidonic acid induced coronary reactions.

  1984cites this paper
• Mechanism of selenium-glutathione peroxidase and its inhibition by mercaptocarboxylic acids and other mercaptans.

  1984cites this paper
• Subcellular localization of the PGE2 synthesis activity in mouse resident peritoneal macrophages

  1984cites this paper
• New aspects of glutathione biochemistry and transport: selective alteration of glutathione metabolism.

  1984cites this paper
• Role of glutathione in gastric mucosal cytoprotection.

  1984cites this paper
• 6 – Inhibitors of Leukotriene Synthesis and Action

  1984cites this paper
• Growth inhibition and prostaglandin metabolism in the R3230AC mammary adenocarcinoma by reduced glutathione.

  1984cites this paper
• Selective modification of glutathione metabolism.

  1983cites this paper
• Glutathione.

  1983cites this paper
• Leukotrienes.

  1983cites this paper
• 16 Enzymes in the Biosynthesis and Catabolism of the Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes and Hydroxy Fatty Acids

  1983cites this paper
• Separation of major prostaglandins, leukotrienes, and monoHETEs by high performance liquid chromatography.

  1983cites this paper
• Biochemical Mechanisms of Macrophage Activation by Lymphokines

  1983cites this paper
• Kinetic comparison and regulation of the cascade of microsomal enzymes involved in renal arachidonate and endoperoxide metabolism.

  1983cites this paper
• Glutathione elevation during thermotolerance induction and thermosensitization by glutathione depletion.

  1983cites this paper
• Secretion of leukotriene C and other arachidonic acid metabolites by macrophages challenged with immunoglobulin E immune complexes

  1982influential citation
• Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis.

  1982cites this paper
• Prostaglandin and protection of the gastroduodenal mucosa.

  1982cites this paper