Reaper‐induced apoptosis in a vertebrate system

No abstract is available for this paper.

• Publication year

  1997

• Venue

  EMBO Journal

• Publication date

  1997-12-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/emboj/16.24.7372PMID 9405366PMCID PMC1170337
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The TNF Receptor I-Associated Protein TRADD Signals Cell Death and NF-KB Activation

  2003cited by this paper
• Interaction between the C. elegans cell-death regulators CED-9 and CED-4

  1997cited by this paper
• Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

  1997cited by this paper
• The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

  1997cited by this paper
• Characterization of reaper- and FADD-induced apoptosis in a lepidopteran cell line

  1997influential reference
• Crk is required for apoptosis in Xenopus egg extracts

  1997cited by this paper
• Interaction of CED-4 with CED-3 and CED-9: A Molecular Framework for Cell Death

  1997cited by this paper
• DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.

  1997cited by this paper
• RAIDD is a new 'death' adaptor molecule

  1997cited by this paper
• Temporal Phases in Apoptosis Defined by the Actions of Src Homology 2 Domains, Ceramide, Bcl-2, Interleukin-1β Converting Enzyme Family Proteases, and a Dense Membrane Fraction

  1997cited by this paper
• Cytochrome c activation of CPP32‐like proteolysis plays a critical role in a Xenopus cell‐free apoptosis system

  1997cited by this paper
• Requirement of an ICE-Like Protease for Induction of Apoptosis and Ceramide Generation by REAPER

  1996cited by this paper
• Cell Killing by the Drosophila Gene reaper

  1996cited by this paper
• FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

  1996cited by this paper
• Apoptotic Activity of REAPER Is Distinct from Signaling by the Tumor Necrosis Factor Receptor 1 Death Domain*

  1996cited by this paper
• Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death.

  1996cited by this paper
• The cell-death machine.

  1996cited by this paper
• Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c.

  1996cited by this paper
• ICE-LAP3, a Novel Mammalian Homologue of the Caenorhabditis elegans Cell Death Protein Ced-3 Is Activated during Fas- and Tumor Necrosis Factor-induced Apoptosis (*)

  1996cited by this paper
• Molecular control of life and death.

  1995cited by this paper
• Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

  1995cited by this paper
• Cell death in health and disease: the biology and regulation of apoptosis.

  1995cited by this paper
• Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

  1995cited by this paper
• FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.

  1995cited by this paper
• Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

  1995cited by this paper
• The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation.

  1995cited by this paper
• Fas Bridging Cell Death and Cytotoxicity: The Reaper Connection

  1995cited by this paper
• Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase.

  1995cited by this paper
• Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

  1995cited by this paper
• The Bcl-2 family of proteins: regulators of cell death and survival.

  1994cited by this paper
• Bcl-2 and the regulation of programmed cell death

  1994cited by this paper
• Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

  1994cited by this paper
• Genetic control of programmed cell death in Drosophila.

  1994cited by this paper
• Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria.

  1994cited by this paper

• Lipopeptides in promoting signals at surface/interface of micelles: Their roles in repairing cellular and nuclear damages

  2022cites this paper
• The Bag6 Complex: Biological Complexity through Modularity

  2017cites this paper
• Cellular characterisation of small Open Reading Frame function in Drosophila melanogaster

  2016cites this paper
• Programmed cell death acts at different stages of Drosophila neurodevelopment to shape the central nervous system

  2016cites this paper
• The Clinical and Translational Implications of Evolutionarily Preserved Intracellular Signalling Pathways

  2015cites this paper
• Apoptosis in Drosophila: which role for mitochondria?

  2015cites this paper
• The Intrinsic Apoptotic Pathway

  2014cites this paper
• Bag6 complex contains a minimal tail-anchor–targeting module and a mock BAG domain

  2014cites this paper
• Methods for the study of caspase activation in the Xenopus laevis oocyte and egg extract.

  2014cites this paper
• D. melanogaster, mitochondria and neurodegeneration: small model organism, big discoveries.

  2013cites this paper
• Apoptosis, redox stress and cancer.

  2013cites this paper
• A Biochemical Screen for Identification of Small-Molecule Regulators of the Wnt Pathway Using Xenopus Egg Extracts

  2011cites this paper
• Mitochondrial fusion is regulated by Reaper to modulate Drosophila programmed cell death

  2011influential citation
• Regulation of Mitochondrial Dynamics during Apoptosis and the Cell Cycle

  2010cites this paper
• Regulation of apoptosis of rbf mutant cells during Drosophila development.

  2009cites this paper
• Transgenic technologies to induce sterility

  2009cites this paper
• Mitochondrial Localization of Reaper to Promote Inhibitors of Apoptosis Protein Degradation Conferred by GH3 Domain-Lipid Interactions*

  2008cites this paper
• Duke University Dissertation Template

  2007cites this paper
• Death by Frustration: How Defects in Cell Differentiation Trigger Apoptosis

  2007cites this paper
• Multifunctional reaper: sixty-five amino acids of fury

  2006cites this paper
• Study of apoptosis in vitro using the Xenopus egg extract reconstitution system.

  2006cites this paper
• From oogenesis through gastrulation: developmental regulation of apoptosis.

  2005cites this paper
• Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2.

  2005cites this paper
• Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability

  2004cites this paper
• Bifunctional killing activity encoded by conserved reaper proteins

  2004cites this paper
• Apoptosis signaling to mitochondria by death receptors and DNA damaging anti-cancer regimens

  2004cites this paper
• A Bax/Bak-independent Mitochondrial Death Pathway Triggered by Drosophila Grim GH3 Domain in Mammalian Cells*

  2004cites this paper
• Regulation of apoptosis by viruses that infect insects.

  2004cites this paper
• Mitochondrial apoptotic pathways induced by Drosophila programmed cell death regulators.

  2003cites this paper
• Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper.

  2003cites this paper
• Reaper Is Regulated by IAP-mediated Ubiquitination*

  2003cites this paper
• A GH3-like Domain in Reaper Is Required for Mitochondrial Localization and Induction of IAP Degradation*

  2003cites this paper
• Viral modulators of cell death provide new links to old pathways.

  2003cites this paper
• Prospects for Using Genetic Transformation for Improved SIT and New Biocontrol Methods

  2002cites this paper
• reaper and bax initiate two different apoptotic pathways affecting mitochondria and antagonized by bcl-2 in Drosophila

  2002cites this paper
• reaper is required for neuroblast apoptosis during Drosophila development.

  2002cites this paper
• GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathway

  2002cites this paper
• The role of ARK in stress-induced apoptosis in Drosophila cells

  2002cites this paper
• B56-Associated Protein Phosphatase 2A Is Required For Survival and Protects from Apoptosis in Drosophila melanogaster

  2002cites this paper
• L’apoptose chez la drosophile : conservation et originalité

  2002cites this paper
• Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

  2002cites this paper
• Apoptotic Regulation by the Crk Adapter Protein Mediated by Interactions with Wee1 and Crm1/Exportin

  2002cites this paper
• L'apoptose chez la drosophile : conservation et

  2002cites this paper
• Post-cytochrome C protection from apoptosis conferred by a MAPK pathway in Xenopus egg extracts.

  2002influential citation
• Regulation of cell number by MAPK-dependent control of apoptosis: a mechanism for trophic survival signaling.

  2002cites this paper
• A Role for G1/S Cyclin-dependent Protein Kinases in the Apoptotic Response to Ionizing Radiation*

  2002cites this paper
• HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation

  2002cites this paper
• Mutations in the Novel Membrane Protein Spinster Interfere with Programmed Cell Death and Cause Neural Degeneration inDrosophila melanogaster

  2001cites this paper
• Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss.

  2001cites this paper
• Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

  2001cites this paper
• Inhibitor of apoptosis proteins (IAPS)

  2001cites this paper
• Analysis of Apoptosis Using Xenopus Egg Extracts

  2001cites this paper
• Cell-free apoptosis in Xenopus laevis egg extracts.

  2000cites this paper
• Regulation and execution of apoptosis during Drosophila development

  2000cites this paper
• Mitochondrion as a novel target of anticancer chemotherapy.

  2000cites this paper
• Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

  2000cites this paper
• Guardian ancestry: fly p53 and damage-inducible apoptosis

  2000cites this paper
• Bcl-2 and Bax mammalian regulators of apoptosis are functional in Drosophila

  2000cites this paper
• The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

  2000cites this paper
• TAK1 Participates in c-Jun N-Terminal Kinase Signaling during Drosophila Development

  2000cites this paper
• Wee1-Regulated Apoptosis Mediated by the Crk Adaptor Protein in Xenopus Egg Extracts

  2000cites this paper
• Molecular mechanisms of cell death and phagocytosis in Drosophila

  2000cites this paper
• Mitochondrial control of apoptosis: an overview.

  1999cites this paper
• Mitochondria at the Crossroad of Apoptotic Cell Death

  1999cites this paper
• Reaper‐induced dissociation of a Scythe‐sequestered cytochrome c‐releasing activity

  1999cites this paper
• Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

  1999cites this paper
• HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis.

  1999cites this paper
• The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

  1999cites this paper
• Death by design: mechanism and control of apoptosis.

  1999cites this paper
• An emerging blueprint for apoptosis in Drosophila.

  1999cites this paper
• Altered Cytochrome c Display Precedes Apoptotic Cell Death in Drosophila

  1999influential citation
• IAP family proteins--suppressors of apoptosis.

  1999cites this paper
• Apoptosis in Drosophila

  1998cites this paper
• The Drosophila inhibitor of apoptosis D‐IAP1 suppresses cell death induced by the caspase drICE

  1998cites this paper
• Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.

  1998cites this paper
• Mechanisms and control of programmed cell death in invertebrates

  1998cites this paper
• Molecular prophets of death in the fly.

  1998cites this paper
• Scythe: a novel reaper‐binding apoptotic regulator

  1998cites this paper
• Drosophila grim induces apoptosis in mammalian cells

  1998influential citation
• INSIGHTS FROM MODEL SYSTEMS Molecular Prophets of Death in the Fly

  1998influential citation
• Apoptosis Induction by Caspase-8 Is Amplified through the Mitochondrial Release of Cytochrome c *

  1998cites this paper
• Apoptosis Genes

  1998cites this paper
• Neuronal cell death.

  1998cites this paper
• Matters of life and death: programmed cell death at Cold Spring Harbor.

  1998cites this paper
• Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes

  1998cites this paper
• SUMMARY reaper is required for neuroblast apoptosis during Drosophila development

  year unknowncites this paper
• AD Award Number : DAMD 1799-1-9177 TITLE : Apoptotic Regulation

  year unknowncites this paper