Resetting the immune system with immunoablation and autologous haematopoietic stem cell transplantation in autoimmune diseases.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Clinical and Experimental Rheumatology

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  PMID 27586805
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.

  2016cited by this paper
• Innate Lymphoid Cells in Graft‐Versus‐Host Disease

  2015cited by this paper
• Functional autoantibodies in systemic sclerosis

  2015cited by this paper
• Autologous hematopoietic stem cell transplantation in multiple sclerosis

  2015cited by this paper
• T cell repertoire following autologous stem cell transplantation for multiple sclerosis.

  2014cited by this paper
• SCT for severe autoimmune diseases: consensus guidelines of the European Society for Blood and Marrow Transplantation for immune monitoring and biobanking

  2014cited by this paper
• Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis.

  2013cited by this paper
• Autoantibodies from long-lived ‘memory’ plasma cells of NZB/W mice drive immune complex nephritis

  2013cited by this paper
• Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: data from the European Group for Blood and Marrow Transplantation registry

  2013cited by this paper
• Bone marrow of NZB/W mice is the major site for plasma cells resistant to dexamethasone and cyclophosphamide: implications for the treatment of autoimmunity.

  2012cited by this paper
• Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus

  2012cited by this paper
• Long-lived autoreactive plasma cells drive persistent autoimmune inflammation

  2011cited by this paper
• Abnormalities of B cell subsets in patients with systemic lupus erythematosus.

  2011cited by this paper
• Immunology. Replacing an immune system gone haywire.

  2010cited by this paper
• Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

  2010cited by this paper
• Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases

  2010cited by this paper
• Regulatory T Cell (Treg) Subsets Return in Patients with Refractory Lupus following Stem Cell Transplantation, and TGF-β-Producing CD8+ Treg Cells Are Associated with Immunological Remission of Lupus1

  2009cited by this paper
• Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system.

  2009cited by this paper
• Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow.

  2009cited by this paper
• Stem cell transplantation for autoimmune diseases: What can we learn from experimental models?

  2008cited by this paper
• Direct Assessment of Thymic Reactivation after Autologous Stem Cell Transplantation

  2008cited by this paper
• Immune re-education following autologous hematopoietic stem cell transplantation

  2008cited by this paper
• Resetting the Adaptive Immune System After Autologous Stem Cell Transplantation: Lessons from Responses to Vaccines

  2007cited by this paper
• Apoptosis and complement-mediated lysis of myeloma cells by polyclonal rabbit antithymocyte globulin.

  2006cited by this paper
• Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network.

  2006cited by this paper
• Treatment of severe autoimmune disease by stem-cell transplantation

  2005cited by this paper
• Analysis of immune reconstitution after autologous bone marrow transplantation in systemic sclerosis.

  2005cited by this paper
• Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients

  2005cited by this paper
• Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis.

  2004cited by this paper
• Differential antibody recognition of the 349–364aa B-cell epitope of human La/SSB protein and its phosphorylated analogue

  2004cited by this paper
• Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

  2004cited by this paper
• Non-myeloablative stem cell transplantation for autoimmune diseases

  2004cited by this paper
• A pilot randomized trial comparing CD34-selected versus unmanipulated hemopoietic stem cell transplantation for severe, refractory rheumatoid arthritis.

  2002cited by this paper
• Two Subsets of Naive T Helper Cells with Distinct T Cell Receptor Excision Circle Content in Human Adult Peripheral Blood

  2002cited by this paper
• Maintaining the norm: T-cell homeostasis

  2002cited by this paper
• Immune reconstitution and immunotherapy after autologous hematopoietic stem cell transplantation.

  1998cited by this paper
• Changes in thymic function with age and during the treatment of HIV infection

  1998cited by this paper
• Regression of adjuvant-induced arthritis in rats following bone marrow transplantation.

  1989cited by this paper

• Defining immune reset: achieving sustained remission in autoimmune diseases

  2025cites this paper
• Autologous stem cell transplantation meets CAR-T therapy: A synergistic strategy for B-cell lymphoma

  2025influential citation
• ATG and other serotherapy in conditioning regimens for autologous HSCT in autoimmune diseases: a survey on behalf of the EBMT Autoimmune Diseases Working Party (ADWP)

  2024cites this paper
• Disease modification in chronic spontaneous urticaria

  2024cites this paper
• Current cell therapies for systemic lupus erythematosus

  2024cites this paper
• Autoantibodies Targeting G-Protein-Coupled Receptors: Pathogenetic, Clinical and Therapeutic Implications in Systemic Sclerosis

  2024cites this paper
• Efficacy and safety of stem cell transplantation for multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials

  2024cites this paper
• Advances in hematopoietic stem cell transplantation for autoimmune diseases

  2024cites this paper
• Advances in the Pathogenesis and Treatment of Systemic Lupus Erythematosus

  2023cites this paper
• When natural antibodies become pathogenic: autoantibodies targeted against G protein-coupled receptors in the pathogenesis of systemic sclerosis

  2023cites this paper
• Efficacy of hematopoietic stem cell transplantation treatment in refractory chronic inflammatory demyelinating polyradiculoneuropathy: a systematic review and meta‐analysis

  2023cites this paper
• Effective and Elaborative Induction Program for Mitigating Myths and Misconceptions Linked to Hematopoietic Stem Cell Transplantation in a Resource Limited Setting

  2023cites this paper
• The use of patient-specific stem cells in different autoimmune diseases

  2022cites this paper
• Infections after Bone Marrow Transplantation Among Irritable Bowel Syndrome Patients: Review Article

  2022cites this paper
• Successful generation of CD19 chimeric antigen receptor (CAR) T cells from patients with advanced Systemic Lupus Erythematosus (SLE).

  2022cites this paper
• Functional autoantibodies in systemic sclerosis: influence of autologous stem cell transplantation and correlation with clinical outcome.

  2022cites this paper
• New insights in systemic lupus erythematosus: From regulatory T cells to CAR-T-cell strategies.

  2022cites this paper
• Long-term follow-up of autologous peripheral blood hematopoietic stem cell transplantation for refractory lupus nephritis—a series study of 20 patients

  2022cites this paper
• Reconstitution of the immune system and clinical correlates after stem cell transplantation for systemic sclerosis

  2022cites this paper
• Rolle von angeborenen Rezeptoren bei chronischen Entzündungen und Autoimmunität

  2022cites this paper
• Immunosuppressive Therapy After Autologous Hematopoietic Stem Cell Transplantation in Systemic Sclerosis Patients—High Efficacy of Rituximab

  2022cites this paper
• AUTOLOGOUS STEM CELL TRANSPLANTATION AND IMMUNOMODULATION IN AMYOTROPHIC LATERAL SCLEROSIS

  2021cites this paper
• Stem Cell Therapy For The Treatment Of Crohn's Disease; Current Obstacles And Future Hopes. (Mini-Review).

  2021cites this paper
• Progress in Liver Transplant Tolerance and Tolerance-Inducing Cellular Therapies

  2020cites this paper
• Autologous Stem Cell Transplantation in Common Variable Immunodeficiency: A Case of Successful Treatment of Severe Refractory Autoimmune Encephalitis

  2020cites this paper
• Haematopoietic stem cell transplantation in systemic sclerosis: Challenges and perspectives.

  2020cites this paper
• Autologous hematopoietic stem cell transplantation in systemic sclerosis induces long-lasting changes in B cell homeostasis toward an anti-inflammatory B cell cytokine pattern

  2019cites this paper
• Alloimmunity and Cholestasis After Liver Transplantation in Children With Progressive Familial Intrahepatic Cholestasis

  2019cites this paper
• Application of Non-invasive Imaging in Inflammatory Disease Conditions to Evaluate Subclinical Coronary Artery Disease

  2019influential citation
• Tolerance regeneration by T regulatory cells in autologous haematopoietic stem cell transplantation for autoimmune diseases

  2019cites this paper
• Rebalancing Immune Homeostasis to Treat Autoimmune Diseases.

  2019cites this paper
• Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis.

  2019cites this paper
• Importance of B cells to development of regulatory T cells and prolongation of tissue allograft survival in recipients receiving autologous bone marrow transplantation

  2018cites this paper
• Adaptationen von T Helferlymphozyten an chronische Entzündungen

  2018cites this paper
• Ocular graft-versus-host disease

  2018cites this paper
• CTLA-4 Mediates Inhibitory Function of Mesenchymal Stem/Stromal Cells

  2018cites this paper
• Reversing Autoimmunity Combination of Rituximab and Intravenous Immunoglobulin

  2018cites this paper
• Allogeneic haematopoietic stem cell transplantation eliminates alloreactive inhibitory antibodies after liver transplantation for bile salt export pump deficiency.

  2018cites this paper
• Hematopoietic stem cell therapy for autoimmune diseases - Clinical experience and mechanisms.

  2018cites this paper
• Increased Pulse Wave Velocity in Systemic Lupus Erythematosus: A Meta-Analysis

  2018cites this paper
• Postsurgical pyoderma gangrenosum after an autologous stem cell transplantation for multiple myeloma

  2018cites this paper
• Challenges and Opportunities for Biomarkers of Clinical Response to AHSCT in Autoimmunity

  2018influential citation
• Cell Therapy: A Therapeutic Option for Multiple Sclerosis

  2018cites this paper
• Homocysteine levels are independently associated with damage accrual in systemic lupus erythematosus patients from a Latin-American cohort

  2018cites this paper
• Lymphocyte reconstitution following autologous stem cell transplantation for progressive MS

  2017cites this paper
• Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: time ready for a paradigm shift?

  2017cites this paper
• Role of Inflammatory Diseases in Hypertension

  2017cites this paper
• Long-term Outcomes of Autologous Peripheral Blood Stem Cell Transplantation for Refractory Rheumatic Diseases

  2017cites this paper
• Progress and prospects for the use and the understanding of the mode of action of autologous hematopoietic stem cell transplantation in the treatment of multiple sclerosis

  2017cites this paper
• Autologe hämatopoetische Stammzelltransplantation bei systemischem Lupus erythematodes

  2016cites this paper
• [Autologous hematopoietic stem cell transplantation in systemic lupus erythematosus].

  2016cites this paper