C-peptide, a novel inhibitor of lung inflammation following hemorrhagic shock.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  American Journal of Physiology - Lung cellular and Molecular Physiology

• Publication date

  2011-03-11

• Fields of study

  Medicine

• Identifiers
  DOI 10.1152/ajplung.00308.2010PMID 21398498PMCID PMC3094028
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• C-Peptide Ameliorates Kidney Injury Following Hemorrhagic Shock

  2011cited by this paper
• Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis.

  2010cited by this paper
• Lung injury after hemorrhage is age dependent: Role of peroxisome proliferator-activated receptor &ggr;*

  2009cited by this paper
• Trauma-hemorrhagic shock-induced pulmonary epithelial and endothelial cell injury utilizes different programmed cell death signaling pathways.

  2009cited by this paper
• Role of extracellular signal-regulated protein kinase (ERK) in 17beta-estradiol-mediated attenuation of lung injury after trauma-hemorrhage.

  2009cited by this paper
• Ciglitazone ameliorates lung inflammation by modulating the inhibitor &kgr;B protein kinase/nuclear factor-&kgr;B pathway after hemorrhagic shock

  2008cited by this paper
• Intracellular Signalling by C-Peptide

  2008cited by this paper
• Human C-peptide antagonises high glucose-induced endothelial dysfunction through the nuclear factor-κB pathway

  2008cited by this paper
• Inhaled ethyl nitrite prevents hyperoxia-impaired postnatal alveolar development in newborn rats.

  2007cited by this paper
• Proinsulin c-peptide exerts beneficial effects in endotoxic shock in mice

  2007cited by this paper
• Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury.

  2006cited by this paper
• The role of the lung in postinjury multiple organ failure.

  2005cited by this paper
• Nuclear factor-kappaB.

  2005cited by this paper
• PPAR-gamma inhibits ANG II-induced cell growth via SHIP2 and 4E-BP1.

  2005cited by this paper
• PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ IS A NEW THERAPEUTIC TARGET IN SEPSIS AND INFLAMMATION

  2005cited by this paper
• Nuclear factor-&kgr;B

  2005cited by this paper
• Potent activation of multiple signalling pathways by C-peptide in opossum kidney proximal tubular cells

  2004cited by this paper
• Inhibition of adipocyte differentiation by mechanical stretching through ERK-mediated downregulation of PPARγ2

  2004cited by this paper
• Ligand-independent activation of peroxisome proliferator-activated receptor-gamma by insulin and C-peptide in kidney proximal tubular cells: dependent on phosphatidylinositol 3-kinase activity.

  2004cited by this paper
• The effect of inhibition of a major cell signaling pathway following trauma hemorrhage on hepatic injury and interleukin 6 levels.

  2004cited by this paper
• Peroxisome Proliferator Activator Receptor-γ Ligands, 15-Deoxy-Δ12,14-Prostaglandin J2 and Ciglitazone, Reduce Systemic Inflammation in Polymicrobial Sepsis by Modulation of Signal Transduction Pathways 1

  2003cited by this paper
• Neutrophils and acute lung injury

  2003cited by this paper
• Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways.

  2003cited by this paper
• Multiple organ failure in trauma patients.

  2003cited by this paper
• Absence of inducible nitric oxide synthase modulates early reperfusion‐induced NF‐κB and AP‐1 activation and enhances myocardial damage

  2002cited by this paper
• Transcriptional mechanisms of acute lung injury.

  2001cited by this paper
• Development of a sensitive multi-well colorimetric assay for active NFkappaB.

  2001cited by this paper
• Development of a sensitive multi-well colorimetric assay for active NFκB

  2001cited by this paper
• Mammalian MAP kinase signalling cascades

  2001cited by this paper
• Role of C-peptide in human physiology.

  2000cited by this paper
• C-peptide exerts cardioprotective effects in myocardial ischemia-reperfusion.

  2000cited by this paper
• The acute respiratory distress syndrome.

  2000cited by this paper
• C‐peptide inhibits leukocyte‐endothelium interaction in the microcirculation during acute endothelial dysfunction

  2000cited by this paper
• NF-kappaB activation.

  2000cited by this paper
• NF-κB activation

  2000cited by this paper
• Specific binding of proinsulin C-peptide to human cell membranes.

  1999cited by this paper
• PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines.

  1998cited by this paper
• The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

  1998cited by this paper
• Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

  1998cited by this paper
• The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation.

  1998cited by this paper
• AP-1 function and regulation.

  1997cited by this paper
• Transcriptional Activation by Peroxisome Proliferator-activated Receptor γ Is Inhibited by Phosphorylation at a Consensus Mitogen-activated Protein Kinase Site*

  1997cited by this paper
• Prevention of vascular and neural dysfunction in diabetic rats by C-peptide.

  1997cited by this paper
• Amelioration by mercaptoethylguanidine of the vascular and energetic failure in haemorrhagic shock in the anesthetised rat.

  1997cited by this paper
• Regulation of Peroxisome Proliferator-activated Receptor γ Activity by Mitogen-activated Protein Kinase*

  1997cited by this paper
• Hemorrhage induces rapid in vivo activation of CREB and NF-kappaB in murine intraparenchymal lung mononuclear cells.

  1997cited by this paper
• The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.

  1994cited by this paper
• The influence of human C-peptide on renal function and glucose utilization in Type 1 (insulin-dependent) diabetic patients

  1992cited by this paper
• Insulin Biosynthesis: Evidence for a Precursor

  1967cited by this paper

• The role of C-peptide in diabetes and its complications: an updated review

  2023cites this paper
• INFLAMMATORY RESPONSE AND METABOLIC ADAPTATION IN CHILDREN WITH ACUTE RESPIRATORY PATHOLOGY.

  2023cites this paper
• Interplay Between the Immune and Endocrine Systems in the Lung: Implications for TB Susceptibility

  2022cites this paper
• Molecular Mechanisms of Action and Physiological Effects of the Proinsulin C-Peptide (a Systematic Review)

  2021cites this paper
• Cyclopentenone Prostaglandins: Biologically Active Lipid Mediators Targeting Inflammation

  2021cites this paper
• Proteome Characterization of BALF Extracellular Vesicles in Idiopathic Pulmonary Fibrosis: Unveiling Undercover Molecular Pathways

  2021cites this paper
• Autocrine C‐peptide protects INS1 β cells against palmitic acid‐induced oxidative stress in peroxisomes by inducing catalase

  2020cites this paper
• [Molecular mechanisms of action and physiological effects of the proinsulin C-peptide (a systematic review)].

  2020cites this paper
• Increase in C-peptide levels after resolution of hyperglycemia in patients with type 2 diabetes mellitus: Myths or facts?

  2020cites this paper
• Role Of C-Peptide In The Vasculature

  2019cites this paper
• Genomewide association study of C-peptide surfaces key regulatory genes in Indians

  2019cites this paper
• Transcriptome profiling of four candidate milk genes in milk and tissue samples of temperate and tropical cattle

  2019cites this paper
• Serum Uric Acid Levels as an Indicator for Metabolically Unhealthy Obesity in Children and Adolescents

  2018cites this paper
• C‐peptide antioxidant adaptive pathways in β cells and diabetes

  2017cites this paper
• C-peptide attenuates acute lung inflammation in a murine model of hemorrhagic shock and resuscitation by reducing gut injury

  2017cites this paper
• The effect of insulin administration on c-peptide in critically ill patients with type 2 diabetes

  2017cites this paper
• Proinsulin C-peptide-mediated signalling and the search for its receptor

  2017cites this paper
• The role of C-peptide in skeletal muscle

  2016cites this paper
• Obesity and pro-inflammatory mediators are associated with acute kidney injury in patients with A/H1N1 influenza and acute respiratory distress syndrome.

  2014cites this paper
• Enhanced insulin action following subcutaneous co‐administration of insulin and C‐peptide in rats

  2014cites this paper
• C-Peptide : A NewMediator of Atherosclerosis in Diabetes

  2014cites this paper
• C-peptide replacement therapy as an emerging strategy for preventing diabetic vasculopathy.

  2014cites this paper
• Combined Zinc Supplementation With Proinsulin C-Peptide Treatment Decreases the Inflammatory Response and Mortality in Murine Polymicrobial Sepsis

  2014cites this paper
• Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction.

  2013cites this paper
• Human C-peptide Quantitation by LC-MS Isotope-Dilution Assay in Serum or Urine Samples

  2013cites this paper
• Effects of the PPAR-β/δ agonist GW0742 during resuscitated porcine septic shock

  2013cites this paper
• Can C‐peptide mediated anti‐inflammatory effects retard the development of microvascular complications of type 1 diabetes?

  2013cites this paper
• C-Peptide: A New Mediator of Atherosclerosis in Diabetes

  2012cites this paper
• New Insights into the Role of Peroxisome Proliferator-Activated Receptors in Regulating the Inflammatory Response after Tissue Injury

  2012cites this paper
• C-Peptide Prevents Hyperglycemia-Induced Endothelial Apoptosis Through Inhibition of Reactive Oxygen Species–Mediated Transglutaminase 2 Activation

  2012cites this paper