Interchangeability of Themis1 and Themis2 in Thymocyte Development Reveals Two Related Proteins with Conserved Molecular Function

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Immunology

• Publication date

  2012-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.1200123PMID 22732588PMCID PMC3401357
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Grb 2 regulates B-cell maturation , B-cell memory responses and inhibits B-cell Ca 2 þ signalling

  2011cited by this paper
• Grb2 regulates B‐cell maturation, B‐cell memory responses and inhibits B‐cell Ca2+ signalling

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• T Cell Receptor (TCR)-induced Tyrosine Phosphorylation Dynamics Identifies THEMIS as a New TCR Signalosome Component

  2010cited by this paper
• Themis2/ICB1 Is a Signaling Scaffold That Selectively Regulates Macrophage Toll-Like Receptor Signaling and Cytokine Production

  2010cited by this paper
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  2010cited by this paper
• Themis controls thymocyte selection through regulation of T cell antigen receptor–mediated signaling

  2009influential reference
• A Novel Gene Essential for the Development of Single Positive Thymocytes

  2009cited by this paper
• Themis, a T cell–specific protein important for late thymocyte development

  2009influential reference
• Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes

  2009cited by this paper
• Themis controls thymocyte selection through regulation of T cell receptor-mediated signaling

  2009cited by this paper
• Function of the Nucleotide Exchange Activity of Vav1 in T Cell Development and Activation

  2009cited by this paper
• Themis is a member of a new metazoan gene family and is required for completion of thymocyte positive selection

  2009influential reference
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  2005cited by this paper
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  2005cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
• RasGRP is essential for mouse thymocyte differentiation and TCR signaling

  2000cited by this paper
• ZAP-70 Is Essential for the T Cell Antigen Receptor-induced Plasma Membrane Targeting of SOS and Vav in T Cells*

  2000cited by this paper
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  1999cited by this paper
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• The JNK Pathway Regulates the In Vivo Deletion of Immature CD4+CD8+ Thymocytes

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  1998influential reference
• Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.

  1998cited by this paper
• BLNK: a central linker protein in B cell activation.

  1998cited by this paper
• Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

  1998cited by this paper
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• SLP-76 expression is restricted to hemopoietic cells of monocyte, granulocyte, and T lymphocyte lineage and is regulated during T cell maturation and activation.

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  1995influential reference
• Ligation of the T-cell antigen receptor (TCR) induces association of hSos1, ZAP-70, phospholipase C-gamma 1, and other phosphoproteins with Grb2 and the zeta-chain of the TCR.

  1995cited by this paper
• Binding of Vav to Grb2 through dimerization of Src homology 3 domains.

  1994influential reference
• Differential effects of zeta and eta transgenes on early alpha/beta T cell development

  1994cited by this paper
• Human CD2 3'-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice.

  1989cited by this paper

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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
• An Update on the Effects of Vitamin D on the Immune System and Autoimmune Diseases

  2022cites this paper
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  2020influential citation
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  2018cites this paper
• Themis-associated phosphatase activity controls signaling in T cell development

  2018cites this paper
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  2017cites this paper
• THEMIS: Two Models, Different Thresholds.

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017influential citation
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  2017cites this paper
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  2016cites this paper
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  2015influential citation
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