Chromoblastomycosis is a subcutaneous mycosis that remains a therapeutic challenge, with no standard treatment and high rates of relapse. On the basis of our recent discoveries in mouse models, we tested the efficacy of topical applications of imiquimod to treat patients afflicted with this chronic fungal infection. We report results of treatment for the first 4 recipients of topical imiquimod, all of whom displayed a marked improvement of their lesions, both with and without concurrent oral antifungal therapy.
Topical Application of Imiquimod as a Treatment for Chromoblastomycosis
Maria da Glória Teixeira De Sousa,W. Belda,R. Spina,Priscila Ramos Lota,N. Valente,Gordon D. Brown,P. Criado,G. Benard
Published 2014 in Clinical Infectious Diseases
ABSTRACT
PUBLICATION RECORD
- Publication year
2014
- Venue
Clinical Infectious Diseases
- Publication date
2014-03-14
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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