Challenges and Opportunities in Transmission Electron Microscopy for Revealing the Fate of Inorganic Nanomaterials in Living Beings

The development of safe and efficient nanomaterials for biomedicine requires understanding their life cycle in the body. In that regards, the multi-functionalities of transmission electron microscopy (TEM) provide the unique opportunity to study at the atomic scale what happens to nanomaterials when they are injected in vitro and in vivo. Over the last 8 years, we have exploited TEM to reveal the biodistribution, the biodegradation and recycling processes of many promising nanomaterials for biomedical applications, including magnetic (Fe and Co nano-oxides), plasmonic (gold) and graphitic (nanotubes) nanostructures [1-7]. Through an overview of these studies, we want to highlight the possibilities and challenges in TEM for revealing the fate of inorganic nanomaterials in the organism.

• Publication year

  2018

• Venue

  Microscopy and Microanalysis

• Publication date

  2018-08-01

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1017/S1431927618008954
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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