Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Virology

• Publication date

  2015-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.virol.2014.12.040PMID 25618414PMCID PMC4455942
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx.

  2015cited by this paper
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  2014influential reference
• Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing.

  2014influential reference
• Structural basis of lentiviral subversion of a cellular protein degradation pathway

  2013influential reference
• HIV accessory proteins versus host restriction factors.

  2013cited by this paper
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  2013influential reference
• The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.

  2012cited by this paper
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  2012influential reference
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  2011cited by this paper
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  2011influential reference
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  2011influential reference
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  2011influential reference
• An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

  2009influential reference
• HIV1 Vpr Arrests the Cell Cycle by Recruiting DCAF1/VprBP, a Receptor of the Cul4-DDB1 Ubiquitin Ligase

  2007influential reference
• HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system

  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• The HIV1 Protein Vpr Acts to Promote G2 Cell Cycle Arrest by Engaging a DDB1 and Cullin4A-containing Ubiquitin Ligase Complex Using VprBP/DCAF1 as an Adaptor*

  2007cited by this paper
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  2007cited by this paper
• E3 ubiquitin ligases.

  2005cited by this paper
• NMR structure of the HIV-1 regulatory protein VPR.

  2003cited by this paper
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  2003cited by this paper
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  1999influential reference
• Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest

  1997cited by this paper
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  1996cited by this paper
• Vpr-induced cell cycle arrest is conserved among primate lentiviruses

  1996cited by this paper
• Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

  1995cited by this paper
• The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle

  1995cited by this paper
• Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr

  1995cited by this paper
• Mosaic genome structure of simian immunodeficiency virus from west African green monkeys.

  1994cited by this paper
• Evolution of the primate lentiviruses: evidence from vpx and vpr.

  1992cited by this paper
• Evolution of the Primates

  1974cited by this paper

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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Xiaohong Zhou ,

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper