A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Glycoconjugate Journal

• Publication date

  2010-06-26

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s10719-010-9297-yPMID 20582467
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The human P(k) histo-blood group antigen provides protection against HIV-1 infection.

  2009influential reference
• Induction of HIV-1 resistance: cell susceptibility to infection is an inverse function of globotriaosyl ceramide levels.

  2008cited by this paper
• Synthetic glycolipid modification of red blood cell membranes

  2007cited by this paper
• A novel soluble mimic of the glycolipid, globotriaosyl ceramide inhibits HIV infection

  2006influential reference
• Biologic and Genetic Characterization of a Panel of 60 Human Immunodeficiency Virus Type 1 Isolates, Representing Clades A, B, C, D, CRF01_AE, and CRF02_AG, for the Development and Assessment of Candidate Vaccines

  2005cited by this paper
• Genetic heterogeneity at the glycosyltransferase loci underlying the GLOB blood group system and collection *

  2004cited by this paper
• E. coli: shiga toxin methods and protocols.

  2003cited by this paper
• HIV‐1 infection is facilitated in T cells by decreasing p56lck protein tyrosine kinase activity

  2003cited by this paper
• Methods for the identification of host receptors for Shiga toxin.

  2003cited by this paper
• Additional molecular bases of the clinically important p blood group phenotype

  2003cited by this paper
• Identification of a Common Sphingolipid-binding Domain in Alzheimer, Prion, and HIV-1 Proteins*

  2002cited by this paper
• Molecular basis of the globoside-deficient P(k) blood group phenotype. Identification of four inactivating mutations in the UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase gene.

  2002cited by this paper
• Molecular Basis of the Globoside-deficient Pk Blood Group Phenotype

  2002cited by this paper
• Membrane raft microdomains in chemokine receptor function.

  2001cited by this paper
• Lipid Rafts and HIV Pathogenesis: Host Membrane Cholesterol Is Required for Infection by HIV Type 1

  2001cited by this paper
• Molecular Basis for the p Phenotype

  2000cited by this paper
• Role of glycosphingolipid microdomains in CD4-dependent HIV-1 fusion

  2000cited by this paper
• Cloning and expression of the histo-blood group Pk UDP-galactose: Ga1beta-4G1cbeta1-cer alpha1, 4-galactosyltransferase. Molecular genetic basis of the p phenotype.

  2000cited by this paper
• Blood group associations with parasites, bacteria, and viruses.

  2000cited by this paper
• Cloning and Expression of the Histo-blood Group PkUDP-galactose:Galβ1–4Glcβ1-Cer α1,4-Galactosyltransferase

  2000cited by this paper
• Molecular Basis for the p Phenotype IDENTIFICATION OF DISTINCT AND MULTIPLE MUTATIONS IN THE a 1,4-GALACTOSYLTRANSFERASE GENE IN SWEDISH AND JAPANESE INDIVIDUALS*

  2000cited by this paper
• Adamantyl globotriaosyl ceramide: a monovalent soluble mimic which inhibits verotoxin binding to its glycolipid receptor.

  1999cited by this paper
• Specific Interaction of HIV-1 and HIV-2 Surface Envelope Glycoproteins with Monolayers of Galactosylceramide and Ganglioside GM3*

  1998cited by this paper
• Sulfatide inhibits HIV-1 entry into CD4-/CXCR4+ cells.

  1998cited by this paper
• CCR5 coreceptor usage of non-syncytium-inducing primary HIV-1 is independent of phylogenetically distinct global HIV-1 isolates: delineation of consensus motif in the V3 domain that predicts CCR-5 usage.

  1998cited by this paper
• SPC3, a V3 loop-derived synthetic peptide inhibitor of HIV-1 infection, binds to cell surface glycosphingolipids.

  1996cited by this paper
• The P blood group system: biochemical, serological, and clinical aspects.

  1995cited by this paper
• Lipid modulation of glycolipid receptor function

  1994cited by this paper
• Lipid modulation of glycolipid receptor function. Availability of Gal(alpha 1-4)Gal disaccharide for verotoxin binding in natural and synthetic glycolipids.

  1994cited by this paper
• Neutral glycosphingolipids of the globo-series characterize activation stages corresponding to germinal center B cells.

  1990cited by this paper

• Gb3 trisaccharide-bearing exosomes as a novel neutralizer for Shiga toxin type 1

  2024cites this paper
• Differential gene expression orchestrated by transcription factors in osteoporosis: bioinformatics analysis of associated polymorphism elaborating functional relationships

  2022cites this paper
• Sphingolipids: Effectors and Achilles Heals in Viral Infections?

  2021cites this paper
• Functions of Sphingolipids in Pathogenesis During Host–Pathogen Interactions

  2021cites this paper
• The Manifold Roles of Sphingolipids in Viral Infections

  2021cites this paper
• Synthetic glycoscapes: addressing the structural and functional complexity of the glycocalyx

  2019cites this paper
• Kode Technology – a universal cell surface glycan modification technology

  2018cites this paper
• Enhancing Attachment of Non-adherent Cells on Inert Surfaces

  2017influential citation
• Why human anti-Galα1-4Galβ1-4Glc natural antibodies do not recognize the trisaccharide on erythrocyte membrane? Molecular dynamics and immunochemical investigation.

  2017cites this paper
• Synthetic glycolipid-like constructs as tools for glycobiology research, diagnostics, and as potential therapeutics

  2015cites this paper
• Sphingolipids in viral infection

  2015cites this paper
• P1PK, GLOB, and FORS blood group systems and GLOB collection: biochemical and clinical aspects. Do we understand it all yet?

  2014cites this paper
• Development of CD19 binding reagents for targeted nanoparticles

  2013influential citation
• Association of Shiga toxin glycosphingolipid receptors with membrane microdomains of toxin-sensitive lymphoid and myeloid cells[S]

  2013cites this paper
• CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide

  2013cites this paper
• Viral infections and sphingolipids.

  2013cites this paper
• An AQP1 allele associated with Co(a–b–) phenotype

  2013cites this paper
• P1PK, Globoside, and FORS Blood Group Systems, Plus Some Other Related Blood Groups

  2013cites this paper
• Modeling transfusion reactions with kodecytes and enabling ABO‐incompatible transfusion with function‐spacer‐lipid constructs

  2012cites this paper
• An improved Fc function assay utilizing CMV antigen‐coated red blood cells generated with synthetic function–spacer–lipid constructs

  2012cites this paper
• Toward creating cell membrane glyco-landscapes with glycan lipid constructs.

  2012cites this paper
• Insights into the manipulation of the immune response to carbohydrate antigens with blood group functional-spacer-lipid constructs

  2012cites this paper
• Procédés in vivo de surveillance de biodistribution

  2012cites this paper
• Designing peptide‐based FSL constructs to create Miltenberger kodecytes

  2011cites this paper
• A novel VSV/HIV pseudotype approach for the study of HIV microbicides without requirement for level 3 biocontainment

  2011cites this paper
• Role of G protein-coupled vasoactive intestinal peptide receptors in HIV integration

  2011cites this paper
• Investigating the Anti-viral Property of Verotoxin and its Receptor Gb3 in Preventing Primary HIV-1 Infection

  2011cites this paper
• Glycosphingolipids in HIV/AIDS: The Potential Therapeutic Application

  2011cites this paper
• Glycosphingolipid functions.

  2011cites this paper
• In vivo neutralization of anti‐A and successful transfusion of A antigen–incompatible red blood cells in an animal model

  2011cites this paper
• FSL constructs: a simple method for modifying cell/virion surfaces with a range of biological markers without affecting their viability.

  2011cites this paper
• The role of glycosphingolipids in HIV/AIDS.

  2011cites this paper
• Comparison of detection methods for cell surface globotriaosylceramide.

  2011cites this paper
• Fluorescein and radiolabeled Function-Spacer-Lipid constructs allow for simple in vitro and in vivo bioimaging of enveloped virions.

  2011cites this paper
• Blood groups and susceptibility to virus infection: new developments

  2010cites this paper
• Multivalent dendrimeric compounds containing carbohydrates expressed on immune cells inhibit infection by primary isolates of HIV-1.

  2010cites this paper