Multiple Genetic Variants in Telomere Pathway Genes and Breast Cancer Risk

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Cancer Epidemiology, Biomarkers and Prevention

• Publication date

  2010-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/1055-9965.EPI-09-0771PMID 20056641PMCID PMC2805470
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A functional promoter polymorphism in the TERT gene does not affect inherited susceptibility to breast cancer.

  2009cited by this paper
• Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

  2009cited by this paper
• Telomere length, oxidative damage, antioxidants and breast cancer risk

  2009cited by this paper
• Genome-wide association study identifies five susceptibility loci for glioma

  2009cited by this paper
• Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

  2008cited by this paper
• A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis

  2008cited by this paper
• Lung cancer susceptibility locus at 5p15.33

  2008cited by this paper
• Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33

  2008cited by this paper
• Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer

  2008cited by this paper
• A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women.

  2008cited by this paper
• Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop.

  2007cited by this paper
• Genome-wide association study identifies novel breast cancer susceptibility loci

  2007influential reference
• Telomere Length Profiles in Humans: All Ends are Not Equal

  2007cited by this paper
• Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer

  2007cited by this paper
• The Genomic Landscapes of Human Breast and Colorectal Cancers

  2007cited by this paper
• Genetic variation in five genes important in telomere biology and risk for breast cancer

  2007cited by this paper
• Association of telomerase gene hTERT polymorphism and malignant gliomas

  2007cited by this paper
• Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial cases.

  2007cited by this paper
• hTERT (-1327)T/C polymorphism is not associated with age-related telomere attrition in peripheral blood.

  2007cited by this paper
• A multidimensional analysis of genes mutated in breast and colorectal cancers.

  2007cited by this paper
• A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

  2007cited by this paper
• Age and menopausal effects of hormonal birth control and hormone replacement therapy in relation to breast cancer risk.

  2006cited by this paper
• Ets2 binding site single nucleotide polymorphism at the hTERT gene promoter--effect on telomerase expression and telomere length maintenance in non-small cell lung cancer.

  2006cited by this paper
• Telomere Length as a Quantitative Trait: Genome-Wide Survey and Genetic Mapping of Telomere Length-Control Genes in Yeast

  2006cited by this paper
• The Consensus Coding Sequences of Human Breast and Colorectal Cancers

  2006cited by this paper
• Coronary artery disease and a functional polymorphism of hTERT.

  2006cited by this paper
• Mapping genetic loci that determine leukocyte telomere length in a large sample of unselected female sibling pairs.

  2006cited by this paper
• Telomere length of normal leukocytes is affected by a functional polymorphism of hTERT.

  2006cited by this paper
• The Genetics of Human Longevity

  2006cited by this paper
• Body size changes in relation to postmenopausal breast cancer among women on Long Island, New York.

  2005cited by this paper
• Switching Human Telomerase On and Off with hPOT1 Protein in Vitro*

  2005cited by this paper
• Cancer and aging: the importance of telomeres in genome maintenance.

  2005cited by this paper
• Telomeres and human disease: ageing, cancer and beyond

  2005cited by this paper
• Haploview: analysis and visualization of LD and haplotype maps

  2005cited by this paper
• Human Protection of Telomeres 1 (POT1) Is a Negative Regulator of Telomerase Activity In Vitro

  2005cited by this paper
• Going against the grain: chemotaxis and infection in Vibrio cholerae

  2005cited by this paper
• Telomere stability genes are not mutated in osteosarcoma cell lines.

  2005cited by this paper
• Environmental tobacco smoke and breast cancer incidence.

  2004cited by this paper
• A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length.

  2004cited by this paper
• The genetics of human longevity.

  2004cited by this paper
• Telomere Shortening Occurs Early During Breast Tumorigenesis: A Cause of Chromosome Destabilization Underlying Malignant Transformation?

  2004cited by this paper
• Importance of TRF1 for Functional Telomere Structure*

  2004cited by this paper
• Targeted Deletion Reveals an Essential Function for the Telomere Length Regulator Trf1

  2003cited by this paper
• Association of a functional tandem repeats in the downstream of human telomerase gene and lung cancer

  2003cited by this paper
• Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adducts.

  2002cited by this paper
• The Long Island Breast Cancer Study Project: Description of a Multi-Institutional Collaboration to Identify Environmental Risk Factors for Breast Cancer

  2002cited by this paper
• Telomere measurement by quantitative PCR.

  2002cited by this paper
• Regulation of the human telomerase reverse transcriptase gene

  2002cited by this paper
• Genome maintenance mechanisms for preventing cancer

  2001cited by this paper
• Genotype transposer: automated genotype manipulation for linkage disequilibrium analysis

  2001cited by this paper
• Role of Oxidative Stress in Telomere Length Regulation and Replicative Senescence

  2000cited by this paper
• Mammalian telomeres end in a large duplex loop.

  1999cited by this paper
• TRF2 protects human telomeres from end-to-end fusions.

  1998cited by this paper
• Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

  1997cited by this paper
• Telomerase catalytic subunit homologs from fission yeast and human.

  1997cited by this paper
• Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

  1997cited by this paper
• Structure and function of telomeres

  1991cited by this paper
• Structure and function of telomeres.

  1989cited by this paper
• [Modern epidemiology].

  1971cited by this paper

• Long-Read Amplicon Sequencing for the Detection of TERT Promoter Variant Clonal Hematopoiesis in Patients with Telomere Biology Disorders.

  2026cites this paper
• Biologically targeted discovery-replication scan identifies G×G interaction in relation to risk of Barrett’s esophagus and esophageal adenocarcinoma

  2025cites this paper
• Genetic and epigenetic alterations in night shift nurses with breast cancer: a narrative review

  2025cites this paper
• Association between TERT gene polymorphisms (rs2736100 and rs2736109) and breast cancer risk in the Iranian population: A case-control study

  2024cites this paper
• Telomere Length as a New Risk Marker of Early-Onset Colorectal Cancer

  2023cites this paper
• Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer

  2023cites this paper
• Genetic Variants of the TERT Gene and Telomere Length in Obstructive Sleep Apnea

  2022cites this paper
• Human TERT promoter polymorphism rs2853669 is associated with cancers: an updated meta-analysis

  2021cites this paper
• Telomeres and Cancer

  2021cites this paper
• Large Multicohort Study Reveals a Prostate Cancer Susceptibility Allele at 5p15 Regulating TERT via Androgen Signaling-Orchestrated Chromatin Binding of E2F1 and MYC

  2021cites this paper
• Effect of TRF1 rs3863242 polymorphism on telomere length in omethoate-exposed workers

  2020cites this paper
• Association between functional TERT promoter polymorphism rs2853669 and cervical cancer risk in South Indian women.

  2020cites this paper
• Association between genetic polymorphisms of telomere pathway genes and hydrogen peroxide level in omethoate exposure workers.

  2020cites this paper
• Role of POT1 in Human Cancer

  2020cites this paper
• Genetic polymorphisms, mRNA expression levels of telomere-binding proteins, and associates with telomere damage in PAHs-Exposure workers.

  2019cites this paper
• Exercise, Telomeres, and Cancer: “The Exercise-Telomere Hypothesis”

  2018cites this paper
• Association between TERT rs2853669 polymorphism and cancer risk: A meta-analysis of 9,157 cases and 11,073 controls

  2018cites this paper
• Telomere Maintenance Mechanisms in Cancer

  2018cites this paper
• Association between rs2853669 in TERT gene and the risk and prognosis of human cancer: a systematic review and meta-analysis

  2017cites this paper
• Mechanisms of breast cancer risk in shift workers: association of telomere shortening with the duration and intensity of night work

  2017cites this paper
• Title Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

  2017cites this paper
• Association between rs2853669 in TERT gene and the risk and prognosis of human cancer: a systematic review and meta-analysis.

  2017influential citation
• Polymorphisms in human telomerase reverse transcriptase (hTERT) gene, gene- gene and gene-smoking interaction with susceptibility to gastric cancer in Chinese Han population

  2017cites this paper
• Integrated analysis of promoter methylation and expression of telomere related genes in breast cancer

  2017cites this paper
• Polymorphisms in human telomerase reverse transcriptase (hTERT) gene and susceptibility to gastric cancer in a Turkish population: Hospital-based case-control study.

  2016cites this paper
• Overexpression of Telomerase Reverse Transcriptase Induces Autism-like Excitatory Phenotypes in Mice

  2016cites this paper
• Association between genetic risk score for telomere length and risk of breast cancer

  2016cites this paper
• Integration of Telomere Length Dynamics into Systems Biology Framework: A Review

  2016cites this paper
• Polymorphisms in the telomerase reverse transcriptase promoter are associated with risk of breast cancer: A meta-analysis.

  2016cites this paper
• Genetic insights on the role of telomere dynamics in Chronic Kidney Disease (CKD) regardless of HIV status

  2016influential citation
• Association Between Human Telomerase Reverse Transcriptase Gene Variations and Risk of Developing Breast Cancer

  2016cites this paper
• Association between TERT promoter polymorphisms and acute myeloid leukemia risk and prognosis

  2015cites this paper
• Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations

  2015cites this paper
• Telomere Reverse Transcriptase (TERT) rs2735940 Increases Cancer Risk

  2015cites this paper
• Prognostic impact of telomere maintenance gene polymorphisms on hepatocellular carcinoma patients with chronic hepatitis B

  2014cites this paper
• Expression of shelterin and shelterin-associated genes in breast cancer cell lines

  2014cites this paper
• Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma

  2014cites this paper
• Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk

  2014influential citation
• Reactivation of telomerase reverse transcriptase gene in liver cancer

  2014cites this paper
• Genetic variations in TERT‐CLPTM1L locus are associated with risk of lung cancer in chinese population

  2013cites this paper
• Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

  2013cites this paper
• The Influence of Biological Ageing in the Pathogenesis of Colorectal Cancer

  2013cites this paper
• Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

  2013cites this paper
• Association of TERT rs 2736098 Polymorphism with Cancer Risk : a Meta-analysis

  2012cites this paper
• Association of leukocyte telomere length with type 2 diabetes in mainland Chinese populations.

  2012cites this paper
• HTERT MNS16A polymorphism in breast cancer: a case–control study

  2012cites this paper
• Telomere length as a prognostic marker in breast and lung cancer

  2012influential citation
• Expression of hPOT1 in HeLa cells and the probability of gene variation of hpot1 Exon14 in endometrial cancer are much higher than in other cancers.

  2012cites this paper
• Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survival

  2012cites this paper
• Genetic Variation in Telomere Maintenance Genes, Telomere Length and Breast Cancer Risk

  2012cites this paper
• Telomerase reverse transcriptase locus polymorphisms and cancer risk: a field synopsis and meta-analysis.

  2012cites this paper
• Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry

  2012cites this paper
• Mutational analysis of telomere genes in BRCA1/2-negative breast cancer families with very short telomeres

  2012cites this paper
• Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme

  2011cites this paper
• Telomere Length and TERT Functional Polymorphisms Are Not Associated with Risk of Squamous Cell Carcinoma of the Head and Neck

  2011cites this paper
• Null Results in Brief Telomere Length and TERT Functional Polymorphisms Are Not Associated with Risk of Squamous Cell Carcinoma of the Head and Neck

  2011cites this paper
• Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.

  2011cites this paper
• The transcriptome landscape of Arabidopsis male meiocytes from high-throughput sequencing: the complexity and evolution of the meiotic process.

  2011cites this paper
• A vision of accessible epidemiology.

  2010cites this paper
• Multiple Genetic Variants in Telomere Pathway Genes and Breast Cancer Risk

  2010cites this paper
• Telomere in Cancer Development

  2010cites this paper