Target sequence accessibility limits activation-induced cytidine deaminase activity in primary mediastinal B-cell lymphoma.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Cancer Research

• Publication date

  2007-07-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/0008-5472.CAN-06-2166PMID 17638864
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells.

  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells.

  2006cited by this paper
• AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies.

  2006cited by this paper
• Activation‐induced cytidine deaminase fails to induce a mutator phenotype in the human pre‐B cell line Nalm‐6

  2005cited by this paper
• Allergen Drives Class Switching to IgE in the Nasal Mucosa in Allergic Rhinitis1

  2005cited by this paper
• The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

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• Activation induced cytidine deaminase expression in lymphocyte predominant Hodgkin lymphoma

  2005cited by this paper
• Differential expression of activation‐induced cytidine deaminase (AID) in nodular lymphocyte‐predominant and classical Hodgkin lymphoma

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• Short-Lived Plasmablasts Dominate the Early Spontaneous Rheumatoid Factor Response: Differentiation Pathways, Hypermutating Cell Types, and Affinity Maturation Outside the Germinal Center1

  2005cited by this paper
• Aberrant somatic hypermutation and expression of activation‐induced cytidine deaminase mRNA in mediastinal large B‐cell lymphoma

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  2005cited by this paper
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  2004cited by this paper
• AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity

  2004influential reference
• Gene Expression Profiling of Hairy Cell Leukemia Reveals a Phenotype Related to Memory B Cells with Altered Expression of Chemokine and Adhesion Receptors

  2004cited by this paper
• Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma.

  2004cited by this paper
• Expression of the AID protein in normal and neoplastic B cells.

  2004cited by this paper
• Genome-wide somatic hypermutation.

  2004cited by this paper
• Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

  2004cited by this paper
• Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

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• Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

  2004cited by this paper
• Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch.

  2004cited by this paper
• Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas.

  2003cited by this paper
• Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype.

  2003cited by this paper
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  2003cited by this paper
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• Extrafollicular antibody responses

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• Human uracil–DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

  2003cited by this paper
• Ongoing In Vivo Immunoglobulin Class Switch DNA Recombination in Chronic Lymphocytic Leukemia B Cells1

  2002cited by this paper
• Mediastinal (thymic) large B-cell lymphoma: where do we stand?

  2002cited by this paper
• AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

  2002influential reference
• Molecular mechanism of class switch recombination: linkage with somatic hypermutation.

  2002cited by this paper
• AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts

  2002cited by this paper
• Activation of NF-κB via the IκB Kinase Complex Is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells*

  2001cited by this paper
• T-helper (Th)1/Th2 imbalance in patients with previously untreated B-cell diffuse large cell lymphoma

  2001cited by this paper
• MedB‐1, a human tumor cell line derived from a primary mediastinal large B‐cell lymphoma

  2001cited by this paper
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• Protein estimation directly from SDS-PAGE loading buffer for standardization of samples from cell lysates or tissue homogenates before Western blot analysis.

  2001cited by this paper
• Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

  2001influential reference
• Isotype-switched immunoglobulin genes with a high load of somatic hypermutation and lack of ongoing mutational activity are prevalent in mediastinal B-cell lymphoma.

  2001cited by this paper
• Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme.

  2000cited by this paper
• Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells*

  1999cited by this paper
• Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression

  1997cited by this paper
• Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma.

  1995influential reference
• B-cell non-Hodgkin's lymphoma cell line (Karpas 1106) with complex translocation involving 18q21.3 but lacking BCL2 rearrangement and expression.

  1994cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections.

  1993cited by this paper
• Monoclonality in B-lymphoproliferative disorders detected at the DNA level.

  1990cited by this paper
• Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

  1983cited by this paper

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• Circulating tumor DNA in primary mediastinal large B-cell lymphoma versus classical Hodgkin lymphoma: a retrospective study

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• Characterization of genomic alterations in CIITA and their functional and clinical implications in malignant lymphomas

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• Characterization of memory B cells from thymus and its impact for DLBCL classification.

  2016cites this paper
• Identification and characterization of novel recurrent mutations in primary mediastinal large B cell lymphoma and Hodgkin lymphoma.

  2015cites this paper
• Genomic Alterations in CIITA Are Frequent in Primary Mediastinal Large B Cell Lymphoma and Are Associated with Diminished MHC Class II Expression.

  2015cites this paper
• Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma

  2014cites this paper
• The molecular pathogenesis of primary mediastinal large B-cell lymphoma.

  2011cites this paper
• AID in Immunodeficiency and Cancer

  2010cites this paper
• Primary mediastinal B‐cell lymphoma in the pediatric patient: Can a rational approach to therapy be based on adult studies?

  2009cites this paper
• Immunoglobulin gene alterations in the progression of B cell lymphomas

  2008cites this paper