Developmental Changes in Hemodynamic Responses and Cardiovagal Modulation during Isometric Handgrip Exercise

The purpose of this study was to examine differences in pressor response and cardiovagal modulation during isometric handgrip exercise (IHG) between children and adults. Beat-to-beat heart rate (HR) and blood pressure were measured in 23 prepubertal children and 23 adults at baseline and during IHG. Cardiovagal modulation was quantified by analysis of HR variability. Mean arterial pressure responses to IHG were greater in adults compared to children (P < .05) whereas there were no group differences in HR responses (P > .05). Children had a greater reduction in cardiovagal modulation in response to IHG compared to adults (P < .05). Changes in mean arterial pressure during IHG were correlated with baseline cardiovagal modulation and force produced during isometric contraction (P < .05). In conclusion, differences in pressor reflex response between children and adults cannot be solely explained by differences in autonomic modulation and appear to be associated with factors contributing to the force produced during isometric contraction.

• Publication year

  2010

• Venue

  International Journal of Pediatrics

• Publication date

  2010-08-29

• Fields of study

  Medicine

• Identifiers
  DOI 10.1155/2010/153780PMID 20862202PMCID 2938431
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• Heart rate responses to isometric handgrip exercise did not differ between children and adults.

  Confidence 0.93

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• Changes in mean arterial pressure during isometric handgrip exercise were correlated with baseline cardiovagal modulation and with force produced during isometric contraction.

  Confidence 0.95

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• Children showed a greater reduction in cardiovagal modulation in response to isometric handgrip exercise than adults.

  Confidence 0.97

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• Mean arterial pressure responses during isometric handgrip exercise were greater in adults than in children.

  Confidence 0.98

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review

• adults

  population, participant group

  The adult participant group consisting of 23 adults compared against the child group.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• cardiovagal modulation

  physiological measure, autonomic measure

  The vagal control of heart rate assessed from heart rate variability in this study.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• force produced during isometric contraction

  mechanical measure, task variable

  The contraction force generated by participants during the isometric handgrip task.

  Aliases: force produced, isometric contraction force

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• heart rate response

  physiological measure, outcome

  The change in heart rate measured from baseline to isometric handgrip exercise.

  Aliases: HR response

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• isometric handgrip exercise

  exercise, task

  A sustained static handgrip task used as the exercise challenge in this comparison of autonomic and hemodynamic responses.

  Aliases: IHG

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• mean arterial pressure

  physiological measure, outcome

  The beat-to-beat arterial pressure measure used to quantify the pressor response during baseline and handgrip exercise.

  Aliases: MAP

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review
• prepubertal children

  population, participant group

  The child participant group consisting of 23 prepubertal individuals compared with adults.

  Aliases: children

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) review

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